CA951319A - Piperazinylalkyl-quinazolone-(4) derivatives, process for their production and pharmaceutical products containing them - Google Patents

Piperazinylalkyl-quinazolone-(4) derivatives, process for their production and pharmaceutical products containing them

Info

Publication number
CA951319A
CA951319A CA114,709,A CA114709A CA951319A CA 951319 A CA951319 A CA 951319A CA 114709 A CA114709 A CA 114709A CA 951319 A CA951319 A CA 951319A
Authority
CA
Canada
Prior art keywords
piperazinylalkyl
quinazolone
derivatives
production
products containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA114,709,A
Other languages
English (en)
Other versions
CA114709S (en
Inventor
Wolfgang Schoetensack
Hermann Amschler
Kurt Klemm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Byk Gulden Lomberg Chemische Fabrik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chemische Fabrik GmbH filed Critical Byk Gulden Lomberg Chemische Fabrik GmbH
Application granted granted Critical
Publication of CA951319A publication Critical patent/CA951319A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA114,709,A 1970-06-05 1971-06-03 Piperazinylalkyl-quinazolone-(4) derivatives, process for their production and pharmaceutical products containing them Expired CA951319A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702027645 DE2027645A1 (de) 1970-06-05 1970-06-05 Piperazinylalkyl chinazolon (4) den vate, Verfahren zu deren Herstellung und sie enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
CA951319A true CA951319A (en) 1974-07-16

Family

ID=5773104

Family Applications (1)

Application Number Title Priority Date Filing Date
CA114,709,A Expired CA951319A (en) 1970-06-05 1971-06-03 Piperazinylalkyl-quinazolone-(4) derivatives, process for their production and pharmaceutical products containing them

Country Status (10)

Country Link
US (1) US3984555A (de)
AT (3) AT318628B (de)
BE (1) BE768137A (de)
CA (1) CA951319A (de)
CH (3) CH569732A5 (de)
DE (1) DE2027645A1 (de)
FR (1) FR2100726B1 (de)
GB (1) GB1331522A (de)
LU (1) LU63267A1 (de)
NL (1) NL7107695A (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4287341A (en) * 1979-11-01 1981-09-01 Pfizer Inc. Alkoxy-substituted-6-chloro-quinazoline-2,4-diones
US6723727B1 (en) * 1996-12-20 2004-04-20 Hoechst Aktiengesellschaft Substituted purine derivatives, processes for their preparation, their use, and compositions comprising them
EP0903344B1 (de) * 1997-08-21 2011-01-26 Shiseido Co., Ltd. Chinazolin-4-on Derivate, deren Herstellung und deren Verwendung als Haarwuchsmittel oder in äusserlich anzuwendenden Hautpflegemitteln
EP1216242A1 (de) 1999-10-01 2002-06-26 Advanced Medicine, Inc. Macrocyclische quinazolinone und ihre verwendung als lokalanästhetika
US6667300B2 (en) * 2000-04-25 2003-12-23 Icos Corporation Inhibitors of human phosphatidylinositol 3-kinase delta
EP1278748B1 (de) * 2000-04-25 2011-03-23 ICOS Corporation Hemmer der menschlichen phosphatidyl-inositol-3-kinase delta
AUPR201600A0 (en) * 2000-12-11 2001-01-11 Fujisawa Pharmaceutical Co., Ltd. Quinazolinone derivative
WO2003020280A2 (en) * 2001-09-05 2003-03-13 Minerva Biotechnologies Corporation Compositions and use thereof in the treatment of cancer
EP2329822A1 (de) 2001-09-05 2011-06-08 Minerva Biotechnologies Corporation Zusammensetzungen und deren Verwendung zur Behandlung von Krebs
EP1444209A4 (de) 2001-11-07 2005-02-16 Merck & Co Inc Inhibitoren mitotischer kinesine
AUPS019702A0 (en) * 2002-01-29 2002-02-21 Fujisawa Pharmaceutical Co., Ltd. Condensed heterocyclic compounds
JP2005536553A (ja) * 2002-08-21 2005-12-02 サイトキネティクス・インコーポレーテッド 化合物、組成物および方法
JP2006512315A (ja) * 2002-11-04 2006-04-13 エヌピーエス ファーマスーティカルズ インコーポレイテッド カルシリティックとしてのキナゾリノン化合物
EP1646615B1 (de) * 2003-06-06 2009-08-26 Vertex Pharmaceuticals Incorporated Pyrimidin-derivate zur verwendung als modulatoren von atp-bindende kassette transportern
US20050054614A1 (en) * 2003-08-14 2005-03-10 Diacovo Thomas G. Methods of inhibiting leukocyte accumulation
US20050043239A1 (en) * 2003-08-14 2005-02-24 Jason Douangpanya Methods of inhibiting immune responses stimulated by an endogenous factor
EP1761540B1 (de) * 2004-05-13 2016-09-28 Icos Corporation Chinazolinone als inhibitoren der humanen phosphatidylinosit-3-kinase delta
EP1755609A1 (de) * 2004-05-25 2007-02-28 Icos Corporation Verfahren zur behandlung und/oder prävention von überschiessender proliferation von hämatopoetischen zellen
AU2006214190A1 (en) * 2005-02-17 2006-08-24 Icos Corporation Phosphoinositide 3-kinase inhibitors for inhibiting leukocyte accumulation
EP2233472B1 (de) * 2006-03-28 2014-01-15 Atir Holding S.A. Heterocyclische verbindungen und deren verwendung bei der behandlung von sexualstörungen
US9492449B2 (en) 2008-11-13 2016-11-15 Gilead Calistoga Llc Therapies for hematologic malignancies
CA3092449A1 (en) 2008-11-13 2010-05-20 Gilead Calistoga Llc Therapies for hematologic malignancies
MX2011009955A (es) 2009-03-24 2011-11-18 Gilead Calistoga Llc Atropisomeros de derivados de 2-purinil-3-tolil-quinazolinona y metodos de uso.
CN102458410A (zh) * 2009-04-20 2012-05-16 吉联亚·卡利斯托加有限责任公司 治疗实体瘤的方法
MX2012000817A (es) 2009-07-21 2012-05-08 Gilead Calistoga Llc Tratamiento para desordenes del higado con inhibidores pi3k.
BRPI1003506B1 (pt) 2010-09-24 2019-12-03 Ache Int Bvi Ltd composto alquil-piperazino-fenil-4(3h)quinazolinonas e uso do composto alquil-piperazino-fenil-4(3h)quinazolinonas associado aos receptores serotoninérgicos 5-ht1a e 5-ht2a
US9353067B2 (en) 2011-04-10 2016-05-31 Atir Holding S.A. Heterocyclic compounds and uses thereof in the treatment of sexual disorders
AU2013203620B2 (en) 2012-03-05 2015-11-19 Gilead Calistoga Llc Polymorphic forms of (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
ES2595240T3 (es) 2012-07-09 2016-12-28 Lupin Limited Derivados de tetrahidroquinazolinona como inhibidores de PARP
PL3083630T3 (pl) 2013-12-20 2020-02-28 Gilead Calistoga Llc Sposoby otrzymywania inhibitorów 3-kinazy fosfatydyloinozytolu
JP2017500319A (ja) 2013-12-20 2017-01-05 ギリアード カリストガ エルエルシー （ｓ）−２−（１−（９ｈ−プリン−６−イルアミノ）プロピル）−５−フルオロ−３−フェニルキナゾリン−４（３ｈ）−オンの塩酸塩の多形形態
NZ726360A (en) 2014-06-13 2018-04-27 Gilead Sciences Inc Phosphatidylinositol 3-kinase inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1249281B (de) * 1963-05-18

Also Published As

Publication number Publication date
US3984555A (en) 1976-10-05
DE2027645A1 (de) 1971-12-09
NL7107695A (de) 1971-12-07
FR2100726B1 (de) 1975-10-10
BE768137A (fr) 1971-12-06
AT318615B (de) 1974-11-11
FR2100726A1 (de) 1972-03-24
CH557829A (de) 1975-01-15
CH569732A5 (de) 1975-11-28
LU63267A1 (de) 1972-08-23
AT317899B (de) 1974-09-25
GB1331522A (en) 1973-09-26
CH558374A (de) 1975-01-31
AT318628B (de) 1974-11-11

Similar Documents

Publication Publication Date Title
CA951319A (en) Piperazinylalkyl-quinazolone-(4) derivatives, process for their production and pharmaceutical products containing them
CA923898A (en) Process for the preparation of new phenyl-imidazolyl-alkanyl derivatives and products thereby produced
CA1008620A (en) Process and apparatus for making pile-surfaced products
CA935025A (en) Poultry product and process for producing same
AU471079B2 (en) 5, 9, 13-prostatrienoic acid derivatives and process for their preparation
CA986140A (en) 3,4-dihydroxy-benzylalcohol derivatives and process for preparing same
AU2207570A (en) Pyridinesulfonic acids, process for their manufacture and pharmaceutical preparations containing them
CA971152A (en) Product and process
IL36917A (en) Dibenzothiepinopyrrole derivatives,their production and pharmaceutical compositions containing them
GB1407529A (en) 1,2-dihydroindene-2-spiro-2-piperazine derivatives and process for production thereof
CA942304A (en) Nitrofuryl-amidine derivatives and process for their preparation
CA963472A (en) Cycloalkano-quinolone derivatives and process for their preparation
IL37888A (en) 3-phenyl-2-alkoxycarbonylaminophenyl-6(7)alkoxycarbonylamino-4-quinazolone derivatives,their production and pharmaceutical compositions containing them
AU469309B2 (en) Nitrofurane derivatives and process for production thereof
CA842787A (en) Decomposition products of .delta.4,20,22-bufatrienolides and process for their separation
AU452006B2 (en) 3 guanidinoalkyl thiphenes, process for their manufacture and pharmaceutical preparations containing them
AU425975B2 (en) Novel 3, 4-dihydroxy-benzylalcohol derivatives and process for preparing same
CA840886A (en) Process for preparing structural elements and product thereof
AU434713B2 (en) Pharmaceutical preparatins containing glucose compounds, glucose derivatives and process for their manufacture
AU2749571A (en) 3 guanidinoalkyl thiphenes, process for their manufacture and pharmaceutical preparations containing them
CA859756A (en) Naphthyridene derivatives and processes for their production
AU475269B2 (en) Process for preparing 1,2,4,5-tetrahydro-3h, 3-benzazepines and products obtained thereby
CA832484A (en) Substituted 1-phenoxy-3-alkylamino-propanoles(2) and process for their production
CA845073A (en) Process for preparing cereal product
CA848916A (en) Process for preparing cereal product