CA948638A - 2-(2'-(.alpha.-HYDROXY-ARYLMETHYL)-ARYL)-2-IMIDAZOLINE DERIVATIVES - Google Patents

2-(2'-(.alpha.-HYDROXY-ARYLMETHYL)-ARYL)-2-IMIDAZOLINE DERIVATIVES

Info

Publication number
CA948638A
CA948638A CA042,441A CA42441A CA948638A CA 948638 A CA948638 A CA 948638A CA 42441 A CA42441 A CA 42441A CA 948638 A CA948638 A CA 948638A
Authority
CA
Canada
Prior art keywords
arylmethyl
aryl
alpha
hydroxy
imidazoline derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA042,441A
Other languages
English (en)
Inventor
Werner Metlesics
Leo H. Sternbach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of CA948638A publication Critical patent/CA948638A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/41—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrogenolysis or reduction of carboxylic groups or functional derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/22—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA042,441A 1968-03-07 1969-02-10 2-(2'-(.alpha.-HYDROXY-ARYLMETHYL)-ARYL)-2-IMIDAZOLINE DERIVATIVES Expired CA948638A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71120268A 1968-03-07 1968-03-07

Publications (1)

Publication Number Publication Date
CA948638A true CA948638A (en) 1974-06-04

Family

ID=24857164

Family Applications (1)

Application Number Title Priority Date Filing Date
CA042,441A Expired CA948638A (en) 1968-03-07 1969-02-10 2-(2'-(.alpha.-HYDROXY-ARYLMETHYL)-ARYL)-2-IMIDAZOLINE DERIVATIVES

Country Status (17)

Country Link
US (1) US3717658A (xx)
JP (1) JPS4843757B1 (xx)
AT (2) AT282623B (xx)
BE (2) BE729432A (xx)
BR (2) BR6906859D0 (xx)
CA (1) CA948638A (xx)
CH (2) CH541573A (xx)
DE (2) DE1910933A1 (xx)
ES (2) ES364423A1 (xx)
FR (2) FR2003407A1 (xx)
GB (2) GB1187009A (xx)
HU (2) HU164902B (xx)
IE (2) IE33111B1 (xx)
IL (3) IL31558A (xx)
NL (2) NL6902846A (xx)
NO (2) NO126084B (xx)
SE (1) SE347511B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3879415A (en) * 1967-03-30 1975-04-22 Hoffmann La Roche Novel 2{8 2-(1,3-diazacycloalk-2-enyl){9 benzophenone derivatives and novel 1,3-diazacycloalkenyl {8 2,1-a{9 {0 isoindole derivatives
US3935218A (en) * 1968-09-05 1976-01-27 American Home Products Corporation Imidazolinyl phenyl carbonyl compounds acid addition salts and related compounds
US3852303A (en) * 1969-03-05 1974-12-03 Sandoz Ag PROCESS FOR IMIDAZO{8 2,1-a{9 ISOINDOLES AND INTERMEDIATES
CH531511A (de) * 1969-03-05 1972-12-15 Sandoz Ag Verfahren zur Herstellung des N,o-Dilithium-Derivats von 2-Phenyl-2-imidazolin
US3931218A (en) * 1973-02-14 1976-01-06 American Home Products Corporation 2-(N-alkyl-2-imidazolin-2-yl)benzophenones and process for their preparation
US3992400A (en) * 1974-04-04 1976-11-16 The Upjohn Company 1-(α-Phenyl-o-tolyl)imidazoles
US3936471A (en) * 1974-08-07 1976-02-03 American Home Products Corporation (Hexahydrobenzimidazol-2-yl)benzophenones and derivatives
JPS53151759U (xx) * 1977-05-07 1978-11-29

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3888846A (en) * 1967-03-30 1975-06-10 Hoffmann La Roche Process for 2(2-(1,3-diazacycloalk-2-enyl))benzophenone derivatives and 1,3-diazacycloalkenyl(2,1-a)isoindole derivatives

Also Published As

Publication number Publication date
NO126084B (xx) 1972-12-18
IL31580A (en) 1973-01-30
DE1910932A1 (de) 1969-10-16
DE1910933A1 (de) 1969-10-16
GB1185618A (en) 1970-03-25
IE33111L (en) 1969-09-07
BE729432A (xx) 1969-09-08
BR6906858D0 (pt) 1973-05-10
ES364423A1 (es) 1971-02-01
HU164902B (xx) 1974-05-28
IL31558A (en) 1972-10-29
NL6902846A (xx) 1969-09-09
US3717658A (en) 1973-02-20
CH503045A (de) 1971-02-15
BR6906859D0 (pt) 1973-05-10
IE32975B1 (en) 1974-02-06
FR2003407A1 (xx) 1969-11-07
SE347511B (xx) 1972-08-07
NL6902923A (xx) 1969-09-09
IE32975L (en) 1970-09-07
FR2070047A1 (xx) 1971-09-10
JPS4843757B1 (xx) 1973-12-20
IL39056A (en) 1973-01-30
BE729433A (xx) 1969-09-08
AT284112B (de) 1970-09-10
FR2070047B1 (xx) 1974-01-11
CH541573A (de) 1973-09-15
GB1187009A (en) 1970-04-08
IL31558A0 (en) 1969-04-30
AT282623B (de) 1970-07-10
IE33111B1 (en) 1974-03-20
IL31580A0 (en) 1969-04-30
NO123530B (xx) 1971-12-06
HU162976B (xx) 1973-05-28
ES364424A1 (es) 1971-02-01

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