CA933915A - PROCESS FOR PRODUCING 6.alpha., 16.alpha.-DIMETHYL-STEROIDS - Google Patents

PROCESS FOR PRODUCING 6.alpha., 16.alpha.-DIMETHYL-STEROIDS

Info

Publication number
CA933915A
CA933915A CA128567A CA128567A CA933915A CA 933915 A CA933915 A CA 933915A CA 128567 A CA128567 A CA 128567A CA 128567 A CA128567 A CA 128567A CA 933915 A CA933915 A CA 933915A
Authority
CA
Canada
Prior art keywords
alpha
steroids
dimethyl
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA128567A
Other languages
English (en)
Inventor
Mengel Klaus
Domenico Amadeo
Kieslich Klaus
Kerb Ulrich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of CA933915A publication Critical patent/CA933915A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0023—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16
    • C07J5/003—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0095—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 carbon in position 21 is part of carboxylic group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/832—Bacillus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA128567A 1970-11-28 1971-11-25 PROCESS FOR PRODUCING 6.alpha., 16.alpha.-DIMETHYL-STEROIDS Expired CA933915A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2059310A DE2059310C3 (de) 1970-11-28 1970-11-28 diese enthaltende Arzneimittel sowie Verfahren zu ihrer Herstellung

Publications (1)

Publication Number Publication Date
CA933915A true CA933915A (en) 1973-09-18

Family

ID=5789778

Family Applications (1)

Application Number Title Priority Date Filing Date
CA128567A Expired CA933915A (en) 1970-11-28 1971-11-25 PROCESS FOR PRODUCING 6.alpha., 16.alpha.-DIMETHYL-STEROIDS

Country Status (23)

Country Link
US (1) US3828083A (OSRAM)
AR (1) AR193053A1 (OSRAM)
AT (1) AT312824B (OSRAM)
AU (1) AU3598871A (OSRAM)
BE (1) BE775901A (OSRAM)
CA (1) CA933915A (OSRAM)
CH (2) CH591518A5 (OSRAM)
CS (1) CS166787B2 (OSRAM)
DE (1) DE2059310C3 (OSRAM)
DK (1) DK135131C (OSRAM)
EG (1) EG10261A (OSRAM)
ES (1) ES395740A1 (OSRAM)
FI (1) FI49159C (OSRAM)
FR (1) FR2115437B1 (OSRAM)
GB (1) GB1377993A (OSRAM)
HU (1) HU162900B (OSRAM)
IE (1) IE35822B1 (OSRAM)
IL (1) IL38241A (OSRAM)
NL (1) NL7116335A (OSRAM)
RO (1) RO67639A (OSRAM)
SE (1) SE374109B (OSRAM)
SU (1) SU474141A3 (OSRAM)
ZA (1) ZA717489B (OSRAM)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2448662C2 (de) * 1974-10-09 1983-07-21 Schering Ag, 1000 Berlin Und 4619 Bergkamen 6α-Fluor-16α-methyl-1,4,8-pregnatrien-3,20-dion-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
US9198921B2 (en) 2010-04-05 2015-12-01 Reveragen Biopharma, Inc. Non-hormonal steroid modulators of NF-κB for treatment of disease

Also Published As

Publication number Publication date
US3828083A (en) 1974-08-06
GB1377993A (en) 1974-12-18
SE374109B (OSRAM) 1975-02-24
IL38241A0 (en) 1972-01-27
AR193053A1 (es) 1973-03-30
DK135131C (da) 1977-08-08
CS166787B2 (OSRAM) 1976-03-29
EG10261A (en) 1976-04-30
CH591518A5 (OSRAM) 1977-09-30
FR2115437B1 (OSRAM) 1975-04-18
PL74335B1 (OSRAM) 1974-10-30
ES395740A1 (es) 1973-12-01
SU440831A3 (OSRAM) 1974-08-25
SU474141A3 (ru) 1975-06-14
BE775901A (fr) 1972-03-16
AT312824B (de) 1974-01-25
IE35822B1 (en) 1976-05-26
ZA717489B (en) 1972-07-26
FR2115437A1 (OSRAM) 1972-07-07
AU3598871A (en) 1973-05-31
DK135131B (da) 1977-03-07
IL38241A (en) 1975-08-31
IE35822L (en) 1972-05-28
RO67639A (ro) 1982-10-26
FI49159B (OSRAM) 1974-12-31
FI49159C (fi) 1975-04-10
HU162900B (OSRAM) 1973-04-28
DE2059310B2 (de) 1980-03-06
CH617709A5 (OSRAM) 1980-06-13
NL7116335A (OSRAM) 1972-05-30
DE2059310A1 (de) 1972-06-08
DE2059310C3 (de) 1980-10-30

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