CA923491A - Cardenolide-and bufadienolide-3-(2',3'-didesoxyglycosides) and process for their preparation - Google Patents

Cardenolide-and bufadienolide-3-(2',3'-didesoxyglycosides) and process for their preparation

Info

Publication number
CA923491A
CA923491A CA091701A CA91701A CA923491A CA 923491 A CA923491 A CA 923491A CA 091701 A CA091701 A CA 091701A CA 91701 A CA91701 A CA 91701A CA 923491 A CA923491 A CA 923491A
Authority
CA
Canada
Prior art keywords
didesoxyglycosides
bufadienolide
cardenolide
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA091701A
Other languages
English (en)
Other versions
CA91701S (en
Inventor
Lindner Ernst
Radscheit Kurt
Fritsch Werner
Stache Ulrich
Haede Werner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Farbwerke Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE1943901A external-priority patent/DE1943901C3/de
Priority claimed from DE19691943903 external-priority patent/DE1943903B2/de
Application filed by Farbwerke Hoechst AG filed Critical Farbwerke Hoechst AG
Application granted granted Critical
Publication of CA923491A publication Critical patent/CA923491A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J19/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 by a lactone ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
CA091701A 1969-08-29 1970-08-25 Cardenolide-and bufadienolide-3-(2',3'-didesoxyglycosides) and process for their preparation Expired CA923491A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE1943901A DE1943901C3 (de) 1969-08-29 1969-08-29 Cardenolid-3-[2', 3' - didesoxyglykoside] und Verfahren zu ihrer Herstellung, sowie Verwendung dieser Verbindungen zur Bekämpfung von Herzkrankheiten
DE19691943903 DE1943903B2 (de) 1969-08-29 1969-08-29 Verfahren zur Herstellung von Cardenolid- und Bufadienolid-3- [2'J' didesoxy-2'3-oxidoglykosiden], sowie Cxtivao&a-^rß' -didesoxy-2'3' -oxido-glykoside]

Publications (1)

Publication Number Publication Date
CA923491A true CA923491A (en) 1973-03-27

Family

ID=25757845

Family Applications (1)

Application Number Title Priority Date Filing Date
CA091701A Expired CA923491A (en) 1969-08-29 1970-08-25 Cardenolide-and bufadienolide-3-(2',3'-didesoxyglycosides) and process for their preparation

Country Status (16)

Country Link
US (1) US3838146A (ro)
JP (2) JPS5248983B1 (ro)
BE (1) BE755537A (ro)
BG (2) BG20578A3 (ro)
CA (1) CA923491A (ro)
CH (2) CH537375A (ro)
DK (2) DK128738B (ro)
ES (1) ES383115A1 (ro)
FI (1) FI49161C (ro)
FR (1) FR2068530B1 (ro)
GB (1) GB1323775A (ro)
IL (1) IL35113A (ro)
NL (1) NL7012422A (ro)
OA (1) OA03653A (ro)
PL (1) PL80915B1 (ro)
SE (2) SE383521B (ro)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2237144A1 (de) * 1972-07-28 1974-02-14 Hoechst Ag Herzwirksame anhydrotalomethyloside und verfahren zu ihrer herstellung
DE2254060A1 (de) * 1972-11-04 1974-05-16 Hoechst Ag Cardenolid-3-eckige klammer auf 4'-amino-2',3',4'-tridesoxy-glykoside eckige klammer zu und verfahren zu ihrer herstellung
DE2256912C2 (de) * 1972-11-20 1984-04-05 Hoechst Ag, 6230 Frankfurt Digoxigenin-3-[2',3'-didesoxy-glykoside], Verfahren zu ihrer Herstellung und deren Verwendung
US5496806A (en) * 1990-01-23 1996-03-05 R. Erich Klemke Glycoside compounds and production and use thereof
US20120310140A1 (en) 2010-12-01 2012-12-06 Spinal Modulation, Inc. Directed delivery of agents to neural anatomy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1768164A1 (de) * 1968-04-06 1971-10-14 Hoechst Ag Tridesoxypyranoside und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
BE755537A (fr) 1971-03-01
FR2068530B1 (ro) 1973-08-10
FI49161B (ro) 1974-12-31
DK127421B (da) 1973-11-05
BG20578A3 (bg) 1975-12-05
GB1323775A (en) 1973-07-18
ES383115A1 (es) 1972-12-16
SE368570B (ro) 1974-07-08
US3838146A (en) 1974-09-24
CH537375A (de) 1973-05-31
OA03653A (fr) 1971-12-24
JPS5248983B1 (ro) 1977-12-14
BG18864A3 (bg) 1975-03-20
CH537377A (de) 1973-07-13
SE383521B (sv) 1976-03-15
FR2068530A1 (ro) 1971-08-27
IL35113A0 (en) 1970-10-30
FI49161C (fi) 1975-04-10
NL7012422A (ro) 1971-03-02
JPS538697B1 (ro) 1978-03-31
IL35113A (en) 1975-06-25
PL80915B1 (ro) 1975-08-30
DK128738B (da) 1974-06-24

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