CA3236501A1 - Albumin protein for use as an emulsifier and drug carrier - Google Patents

Albumin protein for use as an emulsifier and drug carrier Download PDF

Info

Publication number
CA3236501A1
CA3236501A1 CA3236501A CA3236501A CA3236501A1 CA 3236501 A1 CA3236501 A1 CA 3236501A1 CA 3236501 A CA3236501 A CA 3236501A CA 3236501 A CA3236501 A CA 3236501A CA 3236501 A1 CA3236501 A1 CA 3236501A1
Authority
CA
Canada
Prior art keywords
albumin
protein
protein fraction
drug
emulsion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3236501A
Other languages
English (en)
French (fr)
Inventor
Arthur JAFFEE
Dan Schulz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ESC HOLDINGS L.L.C.
Original Assignee
Ecs Brands Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ecs Brands Ltd filed Critical Ecs Brands Ltd
Publication of CA3236501A1 publication Critical patent/CA3236501A1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5052Proteins, e.g. albumin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/10Foods or foodstuffs containing additives; Preparation or treatment thereof containing emulsifiers
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23PSHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00Shaping or working of foodstuffs characterised by the products
    • A23P10/30Encapsulation of particles, e.g. foodstuff additives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/658Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5169Proteins, e.g. albumin, gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5192Processes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Physiology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Botany (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Peptides Or Proteins (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
CA3236501A 2021-10-26 2022-10-26 Albumin protein for use as an emulsifier and drug carrier Pending CA3236501A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163272088P 2021-10-26 2021-10-26
US63/272,088 2021-10-26
PCT/US2022/047934 WO2023076425A1 (en) 2021-10-26 2022-10-26 Albumin protein for use as an emulsifier and drug carrier

Publications (1)

Publication Number Publication Date
CA3236501A1 true CA3236501A1 (en) 2023-05-04

Family

ID=86158481

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3236501A Pending CA3236501A1 (en) 2021-10-26 2022-10-26 Albumin protein for use as an emulsifier and drug carrier

Country Status (8)

Country Link
US (1) US20250009673A1 (https=)
EP (1) EP4422600A4 (https=)
JP (1) JP2024538322A (https=)
CN (1) CN118574604A (https=)
AU (1) AU2022376283A1 (https=)
CA (1) CA3236501A1 (https=)
MX (1) MX2024005206A (https=)
WO (1) WO2023076425A1 (https=)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT3311805T (lt) * 2005-08-31 2020-04-27 Abraxis Bioscience, Llc Kompozicijos, apimančios silpnai vandenyje tirpius farmacinius agentus ir priešmikrobinius agentus
AU2012280935A1 (en) * 2011-11-10 2013-05-30 Clover Corporation Limited Encapsulation of food ingredients supplements and pharmaceuticals
US20150079235A1 (en) * 2012-03-16 2015-03-19 Jennifer Wright Hemp-Based Infant Formula and Methods of Making Same
WO2019213757A1 (en) * 2018-05-07 2019-11-14 POS Management Corp. Hemp protein and use for microencapsulation
EP3937912A4 (en) * 2019-03-13 2022-12-21 Ulagaraj Selvaraj STABILIZED SOLID NANOPARTICLE FORMULATIONS OF CANNABINOIDS AND CANNABINOID ANALOGUES WITH REDUCED OSTWALD MATURATION FOR ORAL, INHALATIVE, NASAL AND PARENTAL DELIVERY
ES2944721T3 (es) * 2019-09-23 2023-06-23 Unilever Ip Holdings B V Emulsión de aceite en agua que comprende proteína vegetal
WO2021137225A1 (en) * 2020-01-02 2021-07-08 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Floating drug delivery systems comprising cannabinoids

Also Published As

Publication number Publication date
EP4422600A4 (en) 2025-12-10
JP2024538322A (ja) 2024-10-18
CN118574604A (zh) 2024-08-30
EP4422600A1 (en) 2024-09-04
MX2024005206A (es) 2024-09-23
AU2022376283A1 (en) 2024-06-13
WO2023076425A1 (en) 2023-05-04
US20250009673A1 (en) 2025-01-09

Similar Documents

Publication Publication Date Title
Zarrabi et al. Nanoliposomes and tocosomes as multifunctional nanocarriers for the encapsulation of nutraceutical and dietary molecules
Chaves et al. Current applications of liposomes for the delivery of vitamins: a systematic review
Pérez-Pérez et al. Exploring the impact of encapsulation on the stability and bioactivity of peptides extracted from botanical sources: Trends and opportunities
Burgos-Díaz et al. Multilayer emulsions stabilized by vegetable proteins and polysaccharides
Su et al. Nano functional food: Opportunities, development, and future perspectives
McClements Nanoparticle-and microparticle-based delivery systems: Encapsulation, protection and release of active compounds
Chen et al. Hybrid bionanoparticle-stabilized Pickering emulsions for quercetin delivery: effect of interfacial composition on release, lipolysis, and bioaccessibility
Zhang et al. Protein-based high internal phase pickering emulsions: A review of their fabrication, composition and future perspectives in the food industry
JPS63501290A (ja) マイクロカプセル
Chen et al. Recent progress in fish oil-based emulsions by various food-grade stabilizers: Fabrication strategy, interfacial stability mechanism and potential application
CN106072623A (zh) 一种复合纳米乳液的制备方法
Gao et al. Advances in encapsulation systems of Antarctic krill oil: From extraction to encapsulation, and future direction
Yuan et al. Efficient utilization of tea resources through encapsulation: dual perspectives from core material to wall material
Cai et al. Encapsulated microstructures of beneficial functional lipids and their applications in foods and biomedicines
Zabodalova et al. Liposomal beta-carotene as a functional additive in dairy products.
Noore et al. Nanocarriers for controlled release and target delivery of bioactive compounds
CN110101084B (zh) 由蛋黄蛋白肽颗粒稳定的海藻油纳米皮克林乳液与油粉及其制备方法与应用
Shamil et al. Microencapsulated bioactive compounds for fortification of dairy products: A review
Altuntas et al. Enhanced oxidative stability and bioaccessibility of sour cherry kernel byproducts encapsulated by complex coacervates with different wall matrixes by spray-and freeze-drying
US20250009673A1 (en) Albumin protein for use as an emulsifier and drug carrier
CN116376068B (zh) 一种植酸交联淀粉-蛋白质复合物协同稳定的双重乳液及在医药领域的应用
Choudhary et al. Recent Development in Nanoencapsulation of β-Sitosterol and γ-Oryzanol and Food Fortification
Wijaya Microencapsulation strategies for long term protection of ascorbic acid
Zareian et al. Enrichment of food product with vitamin E using different encapsulation methods
Biswas et al. Current use of nanoprotein and application in the development of food products for functional and nutritional benefits

Legal Events

Date Code Title Description
W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-1-1-W10-W00-W200 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: REQUEST OR RESPONSE SUBMITTED ONLINE

Effective date: 20240913

MFA Maintenance fee for application paid

Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 2ND ANNIV.) - SMALL

Year of fee payment: 2

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-1-1-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20241023

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-1-1-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT DETERMINED COMPLIANT

Effective date: 20241023

Free format text: ST27 STATUS EVENT CODE: A-1-1-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20241023

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-1-1-W10-W00-W100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: LETTER SENT

Effective date: 20251215