EP3937912A4 - Stabilized solid nanoparticle formulations of cannabinoids and cannabinoid analogs with reduced ostwald ripening for oral, inhalation, nasal and parenteral drug delivery - Google Patents
Stabilized solid nanoparticle formulations of cannabinoids and cannabinoid analogs with reduced ostwald ripening for oral, inhalation, nasal and parenteral drug delivery Download PDFInfo
- Publication number
- EP3937912A4 EP3937912A4 EP20770054.3A EP20770054A EP3937912A4 EP 3937912 A4 EP3937912 A4 EP 3937912A4 EP 20770054 A EP20770054 A EP 20770054A EP 3937912 A4 EP3937912 A4 EP 3937912A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- cannabinoids
- inhalation
- nasal
- oral
- drug delivery
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229930003827 cannabinoid Natural products 0.000 title 2
- 239000003557 cannabinoid Substances 0.000 title 2
- 238000001016 Ostwald ripening Methods 0.000 title 1
- 229940065144 cannabinoids Drugs 0.000 title 1
- 238000012377 drug delivery Methods 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000002105 nanoparticle Substances 0.000 title 1
- 239000007787 solid Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5123—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5169—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5192—Processes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Optics & Photonics (AREA)
- Nanotechnology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962818041P | 2019-03-13 | 2019-03-13 | |
PCT/US2020/022821 WO2020186246A1 (en) | 2019-03-13 | 2020-03-13 | Stabilized solid nanoparticle formulations of cannabinoids and cannabinoid analogs with reduced ostwald ripening for oral, inhalation, nasal and parenteral drug delivery |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3937912A1 EP3937912A1 (en) | 2022-01-19 |
EP3937912A4 true EP3937912A4 (en) | 2022-12-21 |
Family
ID=72427082
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP20770054.3A Pending EP3937912A4 (en) | 2019-03-13 | 2020-03-13 | Stabilized solid nanoparticle formulations of cannabinoids and cannabinoid analogs with reduced ostwald ripening for oral, inhalation, nasal and parenteral drug delivery |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP3937912A4 (en) |
WO (1) | WO2020186246A1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2022061183A1 (en) * | 2020-09-17 | 2022-03-24 | Luminus Biosciences, Inc, | Stabilized solid nanoparticle formulations of cannabinoids and cannabinoid analogs with reduced ostwald ripening for oral, inhalation, nasal and parenteral drug delivery |
WO2023027673A2 (en) * | 2021-08-24 | 2023-03-02 | Hacettepe Universitesi Rektorluk | A method for obtaining a nanoparticular drug delivery system and a nanoparticular drug delivery system obtained by this method |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090238878A1 (en) * | 2006-07-24 | 2009-09-24 | Chandra Ulagaraj Singh | Solid Nanoparticle Formulation of Water Insoluble Pharmaceutical Substances With Reduced Ostwald Ripening |
EP2243495A1 (en) * | 2008-01-16 | 2010-10-27 | Shenyang Pharmaceutical University | A drug delivery system, its preparation process and use |
WO2013006729A2 (en) * | 2011-07-05 | 2013-01-10 | Wet Inc. | Cannabinoid receptor binding agents, compositions and methods |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5576016A (en) * | 1993-05-18 | 1996-11-19 | Pharmos Corporation | Solid fat nanoemulsions as drug delivery vehicles |
GB0302672D0 (en) * | 2003-02-06 | 2003-03-12 | Astrazeneca Ab | Pharmaceutical formulations |
CA2979184C (en) * | 2015-03-10 | 2020-09-08 | Nanosphere Health Sciences, Llc | Lipid nanoparticle compositions and methods as carriers of cannabinoids in standardized precision-metered dosage forms |
EP3582755A4 (en) * | 2017-02-15 | 2020-12-23 | Molecular Infusions, LLC | Formulations |
-
2020
- 2020-03-13 EP EP20770054.3A patent/EP3937912A4/en active Pending
- 2020-03-13 WO PCT/US2020/022821 patent/WO2020186246A1/en unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090238878A1 (en) * | 2006-07-24 | 2009-09-24 | Chandra Ulagaraj Singh | Solid Nanoparticle Formulation of Water Insoluble Pharmaceutical Substances With Reduced Ostwald Ripening |
EP2243495A1 (en) * | 2008-01-16 | 2010-10-27 | Shenyang Pharmaceutical University | A drug delivery system, its preparation process and use |
WO2013006729A2 (en) * | 2011-07-05 | 2013-01-10 | Wet Inc. | Cannabinoid receptor binding agents, compositions and methods |
Non-Patent Citations (2)
Title |
---|
LUEBBERT CHRISTIAN C. ET AL: "Nanoparticle size and production efficiency are affected by the presence of fatty acids during albumin nanoparticle fabrication", PLOS ONE, vol. 12, no. 12, 27 December 2017 (2017-12-27), pages e0189814, XP055979710, DOI: 10.1371/journal.pone.0189814 * |
See also references of WO2020186246A1 * |
Also Published As
Publication number | Publication date |
---|---|
EP3937912A1 (en) | 2022-01-19 |
WO2020186246A1 (en) | 2020-09-17 |
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