CA3236034A1 - Method for producing compounds, method for producing compound library, compound library, and screening method - Google Patents
Method for producing compounds, method for producing compound library, compound library, and screening method Download PDFInfo
- Publication number
- CA3236034A1 CA3236034A1 CA3236034A CA3236034A CA3236034A1 CA 3236034 A1 CA3236034 A1 CA 3236034A1 CA 3236034 A CA3236034 A CA 3236034A CA 3236034 A CA3236034 A CA 3236034A CA 3236034 A1 CA3236034 A1 CA 3236034A1
- Authority
- CA
- Canada
- Prior art keywords
- amino acid
- limf
- tyr
- acid sequence
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y205/00—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
- C12Y205/01—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
- C40B50/06—Biochemical methods, e.g. using enzymes or whole viable microorganisms
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021-170768 | 2021-10-19 | ||
| JP2021170768 | 2021-10-19 | ||
| PCT/JP2022/038924 WO2023068296A1 (ja) | 2021-10-19 | 2022-10-19 | 化合物の製造方法、化合物ライブラリーの製造方法、化合物ライブラリー及びスクリーニング方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3236034A1 true CA3236034A1 (en) | 2023-04-27 |
Family
ID=86059164
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3236034A Pending CA3236034A1 (en) | 2021-10-19 | 2022-10-19 | Method for producing compounds, method for producing compound library, compound library, and screening method |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20250320471A1 (https=) |
| EP (1) | EP4431519A4 (https=) |
| JP (1) | JPWO2023068296A1 (https=) |
| CN (1) | CN118451088A (https=) |
| CA (1) | CA3236034A1 (https=) |
| WO (1) | WO2023068296A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025089420A1 (ja) * | 2023-10-25 | 2025-05-01 | 国立大学法人東京大学 | 環状化合物の製造方法、化合物ライブラリーの製造方法、スクリーニング方法、及び環状化合物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5605602B2 (ja) | 2007-03-26 | 2014-10-15 | 国立大学法人 東京大学 | 環状ペプチド化合物の合成方法 |
| EP2647721B1 (en) | 2010-12-03 | 2019-02-27 | The University of Tokyo | Peptide with safer secondary structure, peptide library, and production methods for same |
| JP6754997B2 (ja) | 2013-08-26 | 2020-09-16 | 国立大学法人 東京大学 | 大環状ペプチド、その製造方法、及び大環状ペプチドライブラリを用いるスクリーニング方法 |
| US20220275534A1 (en) | 2018-10-17 | 2022-09-01 | The University Of Tokyo | Peptide Library Production Method |
-
2022
- 2022-10-19 CN CN202280081706.8A patent/CN118451088A/zh active Pending
- 2022-10-19 EP EP22883600.3A patent/EP4431519A4/en active Pending
- 2022-10-19 JP JP2023554722A patent/JPWO2023068296A1/ja active Pending
- 2022-10-19 US US18/702,964 patent/US20250320471A1/en active Pending
- 2022-10-19 WO PCT/JP2022/038924 patent/WO2023068296A1/ja not_active Ceased
- 2022-10-19 CA CA3236034A patent/CA3236034A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPWO2023068296A1 (https=) | 2023-04-27 |
| WO2023068296A1 (ja) | 2023-04-27 |
| CN118451088A (zh) | 2024-08-06 |
| EP4431519A1 (en) | 2024-09-18 |
| EP4431519A4 (en) | 2025-12-03 |
| US20250320471A1 (en) | 2025-10-16 |
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