CA3231753A1 - Systeme optique holographique sans lentille destine a la detection et a la quantification de la croissance cellulaire et microbienne sans etiquette a haute sensibilite en vue d'un criblage, d'une identification et d'une analyse de sensibilit - Google Patents

Systeme optique holographique sans lentille destine a la detection et a la quantification de la croissance cellulaire et microbienne sans etiquette a haute sensibilite en vue d'un criblage, d'une identification et d'une analyse de sensibilit Download PDF

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Publication number
CA3231753A1
CA3231753A1 CA3231753A CA3231753A CA3231753A1 CA 3231753 A1 CA3231753 A1 CA 3231753A1 CA 3231753 A CA3231753 A CA 3231753A CA 3231753 A CA3231753 A CA 3231753A CA 3231753 A1 CA3231753 A1 CA 3231753A1
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CA
Canada
Prior art keywords
sample
examples
hologram
microorganism
line
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3231753A
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English (en)
Inventor
Oleg Gusyatin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Accelerate Diagnostics Inc
Original Assignee
Accelerate Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US17/474,005 external-priority patent/US20220066390A1/en
Application filed by Accelerate Diagnostics Inc filed Critical Accelerate Diagnostics Inc
Publication of CA3231753A1 publication Critical patent/CA3231753A1/fr
Pending legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0205—Investigating particle size or size distribution by optical means
    • G01N15/0227—Investigating particle size or size distribution by optical means using imaging; using holography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/41—Refractivity; Phase-affecting properties, e.g. optical path length
    • G01N21/45—Refractivity; Phase-affecting properties, e.g. optical path length using interferometric methods; using Schlieren methods
    • G01N21/453—Holographic interferometry

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  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

La divulgation concerne un appareil d'interrogation optique qui peut produire des images sans lentille à l'aide d'un réseau de capteurs optoélectroniques pour générer une image holographique d'objets échantillons, tels que des micro-organismes dans un échantillon. La divulgation concerne également des procédés de détection et/ou d'identification de micro-organismes dans un échantillon biologique, tels que des micro-organismes présents à de faibles niveaux. La divulgation concerne en outre des procédés d'utilisation de systèmes permettant de détecter des micro-organismes dans un échantillon biologique, tels que des micro-organismes présents à de faibles niveaux. De plus ou en variante, les procédés d'utilisation de systèmes permettent d'identifier des micro-organismes présents dans un échantillon et/ou de déterminer la sensibilité antimicrobienne de tels micro-organismes.
CA3231753A 2021-09-13 2022-09-13 Systeme optique holographique sans lentille destine a la detection et a la quantification de la croissance cellulaire et microbienne sans etiquette a haute sensibilite en vue d'un criblage, d'une identification et d'une analyse de sensibilit Pending CA3231753A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17/474,005 US20220066390A1 (en) 2017-07-05 2021-09-13 Lens-free holographic optical system for high sensitivity label-free microbial growth detection and quantification for screening, identification, and susceptibility testing
US17/474,005 2021-09-13
PCT/US2022/043350 WO2023039287A1 (fr) 2021-09-13 2022-09-13 Système optique holographique sans lentille destiné à la détection et à la quantification de la croissance cellulaire et microbienne sans étiquette à haute sensibilité en vue d'un criblage, d'une identification et d'une analyse de sensibilité

Publications (1)

Publication Number Publication Date
CA3231753A1 true CA3231753A1 (fr) 2023-03-16

Family

ID=83594478

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3231753A Pending CA3231753A1 (fr) 2021-09-13 2022-09-13 Systeme optique holographique sans lentille destine a la detection et a la quantification de la croissance cellulaire et microbienne sans etiquette a haute sensibilite en vue d'un criblage, d'une identification et d'une analyse de sensibilit

Country Status (2)

Country Link
CA (1) CA3231753A1 (fr)
WO (1) WO2023039287A1 (fr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10253355B2 (en) 2015-03-30 2019-04-09 Accelerate Diagnostics, Inc. Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing
US11079719B2 (en) * 2017-07-05 2021-08-03 Accelerate Diagnostics, Inc. Lens-free holographic optical system for high sensitivity label-free microbial growth detection and quantification for screening, identification, and susceptibility testing
WO2021154876A1 (fr) * 2020-01-28 2021-08-05 The Regents Of The University Of California Systèmes et procédés pour la détection précoce et la classification de micro-organismes vivants à l'aide d'une imagerie cohérente à intervalles de temps et d'un apprentissage profond

Also Published As

Publication number Publication date
WO2023039287A1 (fr) 2023-03-16

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