CA3231753A1 - Systeme optique holographique sans lentille destine a la detection et a la quantification de la croissance cellulaire et microbienne sans etiquette a haute sensibilite en vue d'un criblage, d'une identification et d'une analyse de sensibilit - Google Patents

Systeme optique holographique sans lentille destine a la detection et a la quantification de la croissance cellulaire et microbienne sans etiquette a haute sensibilite en vue d'un criblage, d'une identification et d'une analyse de sensibilit Download PDF

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Publication number
CA3231753A1
CA3231753A1 CA3231753A CA3231753A CA3231753A1 CA 3231753 A1 CA3231753 A1 CA 3231753A1 CA 3231753 A CA3231753 A CA 3231753A CA 3231753 A CA3231753 A CA 3231753A CA 3231753 A1 CA3231753 A1 CA 3231753A1
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CA
Canada
Prior art keywords
sample
examples
hologram
microorganism
line
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3231753A
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English (en)
Inventor
Oleg Gusyatin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Accelerate Diagnostics Inc
Original Assignee
Accelerate Diagnostics Inc
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Filing date
Publication date
Priority claimed from US17/474,005 external-priority patent/US20220066390A1/en
Application filed by Accelerate Diagnostics Inc filed Critical Accelerate Diagnostics Inc
Publication of CA3231753A1 publication Critical patent/CA3231753A1/fr
Pending legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0205—Investigating particle size or size distribution by optical means
    • G01N15/0227—Investigating particle size or size distribution by optical means using imaging; using holography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/41—Refractivity; Phase-affecting properties, e.g. optical path length
    • G01N21/45—Refractivity; Phase-affecting properties, e.g. optical path length using interferometric methods; using Schlieren methods
    • G01N21/453—Holographic interferometry

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  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

La divulgation concerne un appareil d'interrogation optique qui peut produire des images sans lentille à l'aide d'un réseau de capteurs optoélectroniques pour générer une image holographique d'objets échantillons, tels que des micro-organismes dans un échantillon. La divulgation concerne également des procédés de détection et/ou d'identification de micro-organismes dans un échantillon biologique, tels que des micro-organismes présents à de faibles niveaux. La divulgation concerne en outre des procédés d'utilisation de systèmes permettant de détecter des micro-organismes dans un échantillon biologique, tels que des micro-organismes présents à de faibles niveaux. De plus ou en variante, les procédés d'utilisation de systèmes permettent d'identifier des micro-organismes présents dans un échantillon et/ou de déterminer la sensibilité antimicrobienne de tels micro-organismes.
CA3231753A 2021-09-13 2022-09-13 Systeme optique holographique sans lentille destine a la detection et a la quantification de la croissance cellulaire et microbienne sans etiquette a haute sensibilite en vue d'un criblage, d'une identification et d'une analyse de sensibilit Pending CA3231753A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17/474,005 2021-09-13
US17/474,005 US20220066390A1 (en) 2017-07-05 2021-09-13 Lens-free holographic optical system for high sensitivity label-free microbial growth detection and quantification for screening, identification, and susceptibility testing
PCT/US2022/043350 WO2023039287A1 (fr) 2021-09-13 2022-09-13 Système optique holographique sans lentille destiné à la détection et à la quantification de la croissance cellulaire et microbienne sans étiquette à haute sensibilité en vue d'un criblage, d'une identification et d'une analyse de sensibilité

Publications (1)

Publication Number Publication Date
CA3231753A1 true CA3231753A1 (fr) 2023-03-16

Family

ID=83594478

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3231753A Pending CA3231753A1 (fr) 2021-09-13 2022-09-13 Systeme optique holographique sans lentille destine a la detection et a la quantification de la croissance cellulaire et microbienne sans etiquette a haute sensibilite en vue d'un criblage, d'une identification et d'une analyse de sensibilit

Country Status (2)

Country Link
CA (1) CA3231753A1 (fr)
WO (1) WO2023039287A1 (fr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10253355B2 (en) 2015-03-30 2019-04-09 Accelerate Diagnostics, Inc. Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing
WO2019010327A1 (fr) * 2017-07-05 2019-01-10 Accelerate Diagnostics, Inc. Système optique holographique sans lentille destiné à la détection et à la quantification de la croissance microbienne sans étiquette à haute sensibilité pour criblage, identification et analyse de sensibilité
WO2021154876A1 (fr) * 2020-01-28 2021-08-05 The Regents Of The University Of California Systèmes et procédés pour la détection précoce et la classification de micro-organismes vivants à l'aide d'une imagerie cohérente à intervalles de temps et d'un apprentissage profond

Also Published As

Publication number Publication date
WO2023039287A1 (fr) 2023-03-16

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