CA3220131A1 - Assay devices for combinatorial libraries - Google Patents

Assay devices for combinatorial libraries Download PDF

Info

Publication number
CA3220131A1
CA3220131A1 CA3220131A CA3220131A CA3220131A1 CA 3220131 A1 CA3220131 A1 CA 3220131A1 CA 3220131 A CA3220131 A CA 3220131A CA 3220131 A CA3220131 A CA 3220131A CA 3220131 A1 CA3220131 A1 CA 3220131A1
Authority
CA
Canada
Prior art keywords
well
wells
target
beads
aqueous solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3220131A
Other languages
English (en)
French (fr)
Inventor
Yi Zhang
Jesse Lu
Alex Price
Pengyu YANG
Kandaswamy Vijayan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Plexium Inc
Original Assignee
Plexium Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Plexium Inc filed Critical Plexium Inc
Publication of CA3220131A1 publication Critical patent/CA3220131A1/en
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00Methods of screening libraries
    • C40B30/04Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306Solid-phase reaction mechanisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CA3220131A 2021-04-16 2021-04-16 Assay devices for combinatorial libraries Pending CA3220131A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2021/027769 WO2022220844A1 (en) 2021-04-16 2021-04-16 Assay devices for combinatorial libraries

Publications (1)

Publication Number Publication Date
CA3220131A1 true CA3220131A1 (en) 2022-10-20

Family

ID=83640933

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3220131A Pending CA3220131A1 (en) 2021-04-16 2021-04-16 Assay devices for combinatorial libraries

Country Status (7)

Country Link
EP (1) EP4323100A1 (zh)
JP (1) JP2024516375A (zh)
KR (1) KR20240013103A (zh)
CN (1) CN117440860A (zh)
CA (1) CA3220131A1 (zh)
IL (1) IL307630A (zh)
WO (1) WO2022220844A1 (zh)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2480728A1 (en) * 2002-04-01 2003-10-16 Fluidigm Corporation Microfluidic particle-analysis systems
WO2014028537A1 (en) * 2012-08-14 2014-02-20 10X Technologies, Inc. Microcapsule compositions and methods

Also Published As

Publication number Publication date
KR20240013103A (ko) 2024-01-30
EP4323100A1 (en) 2024-02-21
CN117440860A (zh) 2024-01-23
IL307630A (en) 2023-12-01
WO2022220844A1 (en) 2022-10-20
JP2024516375A (ja) 2024-04-15

Similar Documents

Publication Publication Date Title
Folch et al. Microengineering of cellular interactions
Ueda et al. Emerging applications of superhydrophilic‐superhydrophobic micropatterns
US20100167950A1 (en) Microarray chip and method of fabricating for the same
Yap et al. Protein and cell micropatterning and its integration with micro/nanoparticles assembly
US9200246B2 (en) Co-culture device assembly
US7442515B2 (en) Apparatus and methods for binding molecules and cells
CA2734029C (en) Methods for determining the concentration of an analyte in solution
WO2022098810A1 (en) Assay support devices
Kuddannaya et al. Enhanced in vitro biocompatibility of chemically modified poly (dimethylsiloxane) surfaces for stable adhesion and long-term investigation of brain cerebral cortex cells
KR20170073686A (ko) 세포 배양 인서트
US20020001813A1 (en) Gel pad arrays and methods and systems for making them
US20030166015A1 (en) Multiplexed analysis of cell-substrate interactions
US9476024B2 (en) Thermoresponsive substrate with microgels, method for its preparation and culture method for biological cells
US20090061416A1 (en) Surfaces and methods for biosensor cellular assays
JP2008539755A (ja) ハイスループットスクリーニングのための細胞ベースのプラットフォーム
US11998919B2 (en) Assay devices for combinatorial libraries
CA2724220A1 (en) Microanalysis chip adhesive sheet, microanalysis chip, and manufacturing method thereof
US11911760B2 (en) Caps for assay devices
CA3220131A1 (en) Assay devices for combinatorial libraries
CA3216530A1 (en) Caps for assay devices
JP4328533B2 (ja) 複数の生体分子を規定の比率にて表面に共に固定化する方法及び同方法により形成された表面
Cheng et al. “Chip-on-a-Transwell” Devices for User-Friendly Control of the Microenvironment of Cultured Cells
Gerecsei Development and application of modern biophysical techniques for single-cell and microbead adhesion measurements
US20100279398A1 (en) Instrument and method for treating minor amount of biological material
WO2003076900A2 (en) Multiplexed analysis of cell-substrate interactions