CA3217252A1 - Chimeric cytokine receptors and uses thereof in cellular therapies - Google Patents

Chimeric cytokine receptors and uses thereof in cellular therapies Download PDF

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Publication number
CA3217252A1
CA3217252A1 CA3217252A CA3217252A CA3217252A1 CA 3217252 A1 CA3217252 A1 CA 3217252A1 CA 3217252 A CA3217252 A CA 3217252A CA 3217252 A CA3217252 A CA 3217252A CA 3217252 A1 CA3217252 A1 CA 3217252A1
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domain
cell
amino acid
csfrp
acid sequence
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CA3217252A
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English (en)
French (fr)
Inventor
Qingling JIANG
Yafeng Zhang
Yanliang ZHU
Miaomiao SHI
Shu Wu
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Nanjing Legend Biotechnology Co Ltd
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Nanjing Legend Biotechnology Co Ltd
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Publication of CA3217252A1 publication Critical patent/CA3217252A1/en
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/31—Chimeric antigen receptors [CAR]
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • C07K16/2851—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
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    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
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    • C07K16/303—Liver or Pancreas
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CA3217252A 2021-04-19 2022-04-19 Chimeric cytokine receptors and uses thereof in cellular therapies Pending CA3217252A1 (en)

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Application Number Priority Date Filing Date Title
CNPCT/CN2021/088111 2021-04-19
CN2021088111 2021-04-19
PCT/CN2022/087572 WO2022222905A1 (en) 2021-04-19 2022-04-19 Chimeric cytokine receptors and uses thereof in cellular therapies

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US (1) US20240180964A1 (enExample)
EP (1) EP4326771A4 (enExample)
JP (1) JP2024515181A (enExample)
KR (1) KR20240017338A (enExample)
CN (1) CN117279945A (enExample)
AU (1) AU2022262046A1 (enExample)
CA (1) CA3217252A1 (enExample)
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WO2024254279A2 (en) * 2023-06-06 2024-12-12 The Johns Hopkins University Velocity receptor expressing immune cells and uses thereof
CN121620529A (zh) * 2023-07-31 2026-03-06 南京传奇生物科技有限公司 嵌合细胞因子受体及其使用方法
CN118853563B (zh) * 2024-07-15 2026-04-14 深圳泽医细胞治疗集团有限公司 免疫细胞培养试剂盒、γδT细胞的培养方法及应用

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