CA3215375A1 - Certain n-(1-cyano-2-phenylethyl)-1,4-oxazepane-2-carboxamides for treating cystic fibrosis - Google Patents
Certain n-(1-cyano-2-phenylethyl)-1,4-oxazepane-2-carboxamides for treating cystic fibrosis Download PDFInfo
- Publication number
- CA3215375A1 CA3215375A1 CA3215375A CA3215375A CA3215375A1 CA 3215375 A1 CA3215375 A1 CA 3215375A1 CA 3215375 A CA3215375 A CA 3215375A CA 3215375 A CA3215375 A CA 3215375A CA 3215375 A1 CA3215375 A1 CA 3215375A1
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- Prior art keywords
- patient
- oxazepane
- cyano
- carboxamide
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- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
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- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
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Landscapes
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163181817P | 2021-04-29 | 2021-04-29 | |
| US63/181,817 | 2021-04-29 | ||
| PCT/US2022/027026 WO2022232573A1 (en) | 2021-04-29 | 2022-04-29 | Certain n-(1-cyano-2-phenylethyl)-1,4-oxazepane-2-carboxamides for treating cystic fibrosis |
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| CA3215375A1 true CA3215375A1 (en) | 2022-11-03 |
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| US (1) | US20240226112A1 (https=) |
| EP (1) | EP4329767A4 (https=) |
| JP (1) | JP2024516826A (https=) |
| KR (1) | KR20240004691A (https=) |
| CA (1) | CA3215375A1 (https=) |
| WO (1) | WO2022232573A1 (https=) |
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| NO2699580T3 (https=) | 2014-01-24 | 2018-02-24 | ||
| KR20250002710A (ko) | 2018-03-01 | 2025-01-07 | 아스트라제네카 에이비이 | (2s)-n-｛(1s)-1-시아노-2-[4-(3-메틸-2-옥소-2,3-디하이드로-1,3-벤족사졸-5-일)페닐]에틸｝-1,4-옥사제판-2-카복스아미드를포함하는 약학 조성물 |
| AU2019306532A1 (en) | 2018-07-17 | 2021-03-04 | Insmed Incorporated | Certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamides for treating Lupus Nephritis |
| EP4646265A1 (en) | 2023-01-06 | 2025-11-12 | Insmed Incorporated | Novel, reversible dpp1 inhibitors and uses thereof |
| JP2026510407A (ja) * | 2023-03-23 | 2026-04-02 | ハイスコ ファーマスーティカル プライベート リミテッド | ジペプチジルペプチダーゼ小分子阻害剤を含む医薬組成物 |
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| WO2004076434A1 (en) * | 2003-02-28 | 2004-09-10 | Aic | Dipeptidyl peptidase inhibitors |
| PE20151727A1 (es) * | 2013-03-14 | 2015-12-17 | Boehringer Ingelheim Int | Acido 2-aza-biciclo[2.2.1]heptano-3-carboxilico (bencil-ciano-metil)-amidas sustituidas inhibidores de catepsina c |
| NO2699580T3 (https=) * | 2014-01-24 | 2018-02-24 | ||
| DK3265452T3 (en) * | 2015-03-05 | 2020-06-08 | Neuprozyme Therapeutics ApS | Peptidyl nitril compounds as dipeptidyl peptidase i inhibitors |
| KR20250107292A (ko) * | 2016-07-29 | 2025-07-11 | 인스메드 인코포레이티드 | 기관지확장증을 치료하기 위한 특정 (2s)-n-[(1s)-1-시아노-2-페닐에틸]-1,4-옥사제판-2-카르복스아미드 |
| KR20250002710A (ko) * | 2018-03-01 | 2025-01-07 | 아스트라제네카 에이비이 | (2s)-n-｛(1s)-1-시아노-2-[4-(3-메틸-2-옥소-2,3-디하이드로-1,3-벤족사졸-5-일)페닐]에틸｝-1,4-옥사제판-2-카복스아미드를포함하는 약학 조성물 |
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2022
- 2022-04-29 US US18/288,338 patent/US20240226112A1/en active Pending
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- 2022-04-29 EP EP22796849.2A patent/EP4329767A4/en not_active Withdrawn
- 2022-04-29 KR KR1020237040988A patent/KR20240004691A/ko active Pending
Also Published As
| Publication number | Publication date |
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| WO2022232573A1 (en) | 2022-11-03 |
| KR20240004691A (ko) | 2024-01-11 |
| EP4329767A4 (en) | 2025-03-12 |
| JP2024516826A (ja) | 2024-04-17 |
| US20240226112A1 (en) | 2024-07-11 |
| EP4329767A1 (en) | 2024-03-06 |
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