CA3186974A1 - Methods and compositions for analyzing nucleic acid - Google Patents
Methods and compositions for analyzing nucleic acidInfo
- Publication number
- CA3186974A1 CA3186974A1 CA3186974A CA3186974A CA3186974A1 CA 3186974 A1 CA3186974 A1 CA 3186974A1 CA 3186974 A CA3186974 A CA 3186974A CA 3186974 A CA3186974 A CA 3186974A CA 3186974 A1 CA3186974 A1 CA 3186974A1
- Authority
- CA
- Canada
- Prior art keywords
- nucleic acid
- oligonucleotide
- scaffold
- region
- ssna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2330/00—Production
- C12N2330/30—Production chemically synthesised
- C12N2330/31—Libraries, arrays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Crystallography & Structural Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063043688P | 2020-06-24 | 2020-06-24 | |
| US63/043,688 | 2020-06-24 | ||
| US202063086208P | 2020-10-01 | 2020-10-01 | |
| US63/086,208 | 2020-10-01 | ||
| US202163159174P | 2021-03-10 | 2021-03-10 | |
| US63/159,174 | 2021-03-10 | ||
| US202163195352P | 2021-06-01 | 2021-06-01 | |
| US63/195,352 | 2021-06-01 | ||
| PCT/US2021/038609 WO2021262805A1 (en) | 2020-06-24 | 2021-06-23 | Methods and compositions for analyzing nucleic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3186974A1 true CA3186974A1 (en) | 2021-12-30 |
Family
ID=76943150
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3186974A Pending CA3186974A1 (en) | 2020-06-24 | 2021-06-23 | Methods and compositions for analyzing nucleic acid |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20230235320A1 (https=) |
| EP (2) | EP4428244B1 (https=) |
| JP (2) | JP7802707B2 (https=) |
| CN (1) | CN116096914A (https=) |
| AU (1) | AU2021297880A1 (https=) |
| CA (1) | CA3186974A1 (https=) |
| DK (2) | DK4172357T3 (https=) |
| WO (1) | WO2021262805A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8835358B2 (en) | 2009-12-15 | 2014-09-16 | Cellular Research, Inc. | Digital counting of individual molecules by stochastic attachment of diverse labels |
| WO2021146219A1 (en) | 2020-01-13 | 2021-07-22 | Becton, Dickinson And Company | Cell capture using du-containing oligonucleotides |
| WO2024097719A1 (en) * | 2022-11-02 | 2024-05-10 | Becton, Dickinson And Company | Application for peptide nucleic acid (pna) blocker |
| US20260009070A1 (en) * | 2022-12-16 | 2026-01-08 | Foundation Medicine, Inc. | Library preparation and analytical methods for preserving topological information of cell-free dna |
| EP4731784A2 (en) * | 2023-06-23 | 2026-04-29 | Seqonce Biosciences, Inc. | Nick initiated cycling emission and replacement reaction |
| WO2025106807A1 (en) * | 2023-11-16 | 2025-05-22 | The Board Of Trustees Of The Leland Stanford Junior University | Classification of samples using methylation enrichment |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6927028B2 (en) | 2001-08-31 | 2005-08-09 | Chinese University Of Hong Kong | Non-invasive methods for detecting non-host DNA in a host using epigenetic differences between the host and non-host DNA |
| JP5149013B2 (ja) | 2004-11-29 | 2013-02-20 | セクエノム，インコーポレイティド | メチル化ｄｎａを検出する手段、及び方法 |
| EP3617321B1 (en) | 2006-05-31 | 2024-10-23 | Sequenom, Inc. | Kit for the extraction and amplification of nucleic acid from a sample |
| JP2009540802A (ja) | 2006-06-16 | 2009-11-26 | セクエノム， インコーポレイテッド | サンプルからの核酸を増幅、検出および定量するための方法および組成物 |
| WO2009032779A2 (en) | 2007-08-29 | 2009-03-12 | Sequenom, Inc. | Methods and compositions for the size-specific seperation of nucleic acid from a sample |
| WO2009032781A2 (en) | 2007-08-29 | 2009-03-12 | Sequenom, Inc. | Methods and compositions for universal size-specific polymerase chain reaction |
| WO2009120808A2 (en) | 2008-03-26 | 2009-10-01 | Sequenom, Inc. | Restriction endonuclease enhanced polymorphic sequence detection |
| EP3103871B1 (en) | 2008-09-16 | 2020-07-29 | Sequenom, Inc. | Processes for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for fetal nucleic acid quantification |
| US8476013B2 (en) | 2008-09-16 | 2013-07-02 | Sequenom, Inc. | Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses |
| EP3514244B1 (en) | 2009-04-03 | 2021-07-07 | Sequenom, Inc. | Nucleic acid preparation methods |
| WO2011143659A2 (en) | 2010-05-14 | 2011-11-17 | Fluidigm Corporation | Nucleic acid isolation methods |
| WO2013019361A1 (en) | 2011-07-07 | 2013-02-07 | Life Technologies Corporation | Sequencing methods |
| EP3950944A1 (en) * | 2014-09-15 | 2022-02-09 | AbVitro LLC | High-throughput nucleotide library sequencing |
| ES2898088T3 (es) * | 2016-06-01 | 2022-03-03 | Hoffmann La Roche | Inmuno-PETE |
| AU2018212756B2 (en) * | 2017-01-27 | 2021-02-25 | Integrated Dna Technologies, Inc. | Construction of next generation sequencing (NGS) libraries using competitive strand displacement |
| CN108060191B (zh) * | 2017-11-07 | 2021-05-04 | 深圳华大智造科技股份有限公司 | 一种双链核酸片段加接头的方法、文库构建方法和试剂盒 |
| AU2019207900B2 (en) * | 2018-01-12 | 2025-07-10 | Claret Bioscience, Llc | Methods and compositions for analyzing nucleic acid |
| WO2020206143A1 (en) * | 2019-04-05 | 2020-10-08 | Claret Bioscience, Llc | Methods and compositions for analyzing nucleic acid |
| AU2020345621A1 (en) * | 2019-09-09 | 2022-04-07 | University Of Utah Research Foundation | Targeted sequencing to detect and quantify low levels of methylated DNA |
-
2021
- 2021-06-23 EP EP24175490.2A patent/EP4428244B1/en active Active
- 2021-06-23 CN CN202180058203.4A patent/CN116096914A/zh active Pending
- 2021-06-23 CA CA3186974A patent/CA3186974A1/en active Pending
- 2021-06-23 AU AU2021297880A patent/AU2021297880A1/en active Pending
- 2021-06-23 US US18/011,271 patent/US20230235320A1/en active Pending
- 2021-06-23 DK DK21742627.9T patent/DK4172357T3/da active
- 2021-06-23 DK DK24175490.2T patent/DK4428244T3/da active
- 2021-06-23 EP EP21742627.9A patent/EP4172357B1/en active Active
- 2021-06-23 JP JP2022579952A patent/JP7802707B2/ja active Active
- 2021-06-23 WO PCT/US2021/038609 patent/WO2021262805A1/en not_active Ceased
-
2025
- 2025-09-11 JP JP2025151404A patent/JP2025183345A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20230235320A1 (en) | 2023-07-27 |
| EP4428244B1 (en) | 2025-10-15 |
| EP4172357B1 (en) | 2024-05-15 |
| EP4428244A3 (en) | 2024-10-02 |
| AU2021297880A1 (en) | 2023-01-19 |
| CN116096914A (zh) | 2023-05-09 |
| DK4172357T3 (da) | 2024-08-05 |
| JP2023531720A (ja) | 2023-07-25 |
| DK4428244T3 (da) | 2026-01-12 |
| JP2025183345A (ja) | 2025-12-16 |
| WO2021262805A1 (en) | 2021-12-30 |
| EP4172357A1 (en) | 2023-05-03 |
| JP7802707B2 (ja) | 2026-01-20 |
| EP4428244A2 (en) | 2024-09-11 |
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