CA3185278A1 - Filtration assemblies, cassettes, systems, and methods for filtration and cell growth - Google Patents
Filtration assemblies, cassettes, systems, and methods for filtration and cell growthInfo
- Publication number
- CA3185278A1 CA3185278A1 CA3185278A CA3185278A CA3185278A1 CA 3185278 A1 CA3185278 A1 CA 3185278A1 CA 3185278 A CA3185278 A CA 3185278A CA 3185278 A CA3185278 A CA 3185278A CA 3185278 A1 CA3185278 A1 CA 3185278A1
- Authority
- CA
- Canada
- Prior art keywords
- membrane
- cassette
- base
- funnel
- filtration assembly
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000001914 filtration Methods 0.000 title claims abstract description 108
- 238000000034 method Methods 0.000 title claims abstract description 37
- 230000000712 assembly Effects 0.000 title abstract description 18
- 238000000429 assembly Methods 0.000 title abstract description 18
- 230000010261 cell growth Effects 0.000 title description 4
- 239000012528 membrane Substances 0.000 claims description 273
- 239000007787 solid Substances 0.000 claims description 42
- 230000012010 growth Effects 0.000 claims description 30
- 235000015097 nutrients Nutrition 0.000 claims description 26
- 239000012530 fluid Substances 0.000 claims description 12
- 238000003384 imaging method Methods 0.000 claims description 12
- 239000010409 thin film Substances 0.000 claims description 12
- 230000000717 retained effect Effects 0.000 claims description 9
- 230000007246 mechanism Effects 0.000 claims description 8
- 244000005700 microbiome Species 0.000 claims description 8
- 238000012258 culturing Methods 0.000 claims description 6
- 238000003825 pressing Methods 0.000 claims description 6
- 229920002678 cellulose Polymers 0.000 claims description 5
- 239000007788 liquid Substances 0.000 claims description 4
- 239000012488 sample solution Substances 0.000 abstract description 2
- -1 polypropylene Polymers 0.000 description 14
- 239000000463 material Substances 0.000 description 11
- 239000000523 sample Substances 0.000 description 11
- 238000012546 transfer Methods 0.000 description 6
- 229920000139 polyethylene terephthalate Polymers 0.000 description 5
- 239000005020 polyethylene terephthalate Substances 0.000 description 5
- 239000004743 Polypropylene Substances 0.000 description 4
- 241000722921 Tulipa gesneriana Species 0.000 description 4
- 238000011109 contamination Methods 0.000 description 4
- 229920003023 plastic Polymers 0.000 description 4
- 239000004033 plastic Substances 0.000 description 4
- 229920001155 polypropylene Polymers 0.000 description 4
- 238000007789 sealing Methods 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 239000004698 Polyethylene Substances 0.000 description 3
- 239000000853 adhesive Substances 0.000 description 3
- 230000001070 adhesive effect Effects 0.000 description 3
- 238000011534 incubation Methods 0.000 description 3
- 238000002347 injection Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 239000002609 medium Substances 0.000 description 3
- 239000004417 polycarbonate Substances 0.000 description 3
- 229920000515 polycarbonate Polymers 0.000 description 3
- 229920000728 polyester Polymers 0.000 description 3
- 229920000573 polyethylene Polymers 0.000 description 3
- 238000003860 storage Methods 0.000 description 3
- 229920001169 thermoplastic Polymers 0.000 description 3
- 239000002033 PVDF binder Substances 0.000 description 2
- 239000004695 Polyether sulfone Substances 0.000 description 2
- 239000004793 Polystyrene Substances 0.000 description 2
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 2
- 239000004809 Teflon Substances 0.000 description 2
- 229920006362 Teflon® Polymers 0.000 description 2
- 238000004026 adhesive bonding Methods 0.000 description 2
- 229920002301 cellulose acetate Polymers 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 230000003467 diminishing effect Effects 0.000 description 2
- 229920005570 flexible polymer Polymers 0.000 description 2
- 238000010348 incorporation Methods 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 230000000813 microbial effect Effects 0.000 description 2
- 230000002906 microbiologic effect Effects 0.000 description 2
- 239000001967 plate count agar Substances 0.000 description 2
- 229920006393 polyether sulfone Polymers 0.000 description 2
- 229920002223 polystyrene Polymers 0.000 description 2
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 2
- 239000004810 polytetrafluoroethylene Substances 0.000 description 2
- 229920002981 polyvinylidene fluoride Polymers 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 239000012449 sabouraud dextrose agar Substances 0.000 description 2
- 239000006150 trypticase soy agar Substances 0.000 description 2
- 229920001817 Agar Polymers 0.000 description 1
- 241000203069 Archaea Species 0.000 description 1
- 229920000089 Cyclic olefin copolymer Polymers 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 239000000020 Nitrocellulose Substances 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- 239000004696 Poly ether ether ketone Substances 0.000 description 1
- 239000004699 Ultra-high molecular weight polyethylene Substances 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- DQXBYHZEEUGOBF-UHFFFAOYSA-N but-3-enoic acid;ethene Chemical compound C=C.OC(=O)CC=C DQXBYHZEEUGOBF-UHFFFAOYSA-N 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 230000001332 colony forming effect Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- QHSJIZLJUFMIFP-UHFFFAOYSA-N ethene;1,1,2,2-tetrafluoroethene Chemical group C=C.FC(F)=C(F)F QHSJIZLJUFMIFP-UHFFFAOYSA-N 0.000 description 1
- 229920000840 ethylene tetrafluoroethylene copolymer Polymers 0.000 description 1
- 239000005038 ethylene vinyl acetate Substances 0.000 description 1
- 229920001903 high density polyethylene Polymers 0.000 description 1
- 239000004700 high-density polyethylene Substances 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 229920001220 nitrocellulos Polymers 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 229920001200 poly(ethylene-vinyl acetate) Polymers 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 229920002239 polyacrylonitrile Polymers 0.000 description 1
- 229920002530 polyetherether ketone Polymers 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 229920000098 polyolefin Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 229920003048 styrene butadiene rubber Polymers 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 229920000785 ultra high molecular weight polyethylene Polymers 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
- C12M33/14—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus with filters, sieves or membranes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/18—Apparatus therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/08—Flat membrane modules
- B01D63/087—Single membrane modules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
- B01D71/06—Organic material
- B01D71/08—Polysaccharides
- B01D71/12—Cellulose derivatives
- B01D71/14—Esters of organic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/42—Integrated assemblies, e.g. cassettes or cartridges
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/48—Holding appliances; Racks; Supports
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
- C12M25/02—Membranes; Filters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/24—Methods of sampling, or inoculating or spreading a sample; Methods of physically isolating an intact microorganisms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/02—Specific tightening or locking mechanisms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/04—Specific sealing means
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Sustainable Development (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Clinical Laboratory Science (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Water Supply & Treatment (AREA)
- Toxicology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063049513P | 2020-07-08 | 2020-07-08 | |
| US63/049,513 | 2020-07-08 | ||
| PCT/US2021/040935 WO2022011169A1 (en) | 2020-07-08 | 2021-07-08 | Filtration assemblies, cassettes, systems, and methods for filtration and cell growth |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3185278A1 true CA3185278A1 (en) | 2022-01-13 |
Family
ID=79552091
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3185278A Pending CA3185278A1 (en) | 2020-07-08 | 2021-07-08 | Filtration assemblies, cassettes, systems, and methods for filtration and cell growth |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20230257692A1 (zh) |
| EP (1) | EP4179062A4 (zh) |
| JP (1) | JP2023535296A (zh) |
| KR (1) | KR20230035119A (zh) |
| CN (1) | CN116075586A (zh) |
| AU (1) | AU2021305328A1 (zh) |
| CA (1) | CA3185278A1 (zh) |
| WO (1) | WO2022011169A1 (zh) |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2337987A1 (en) * | 2000-02-25 | 2001-08-25 | Elmex Limited | Membrane filtration system |
| US20040063169A1 (en) * | 2002-02-05 | 2004-04-01 | Jeffrey Kane | Filtration assembly |
| JP2005080506A (ja) * | 2003-09-04 | 2005-03-31 | L'air Liquide Sa Pour L'etude & L'exploitation Des Procede S Georges Claude | 低温液体中の微生物のサンプラーおよびサンプリングシステム |
| JP5160428B2 (ja) * | 2005-09-26 | 2013-03-13 | ラピッド マイクロ バイオシステムズ インコーポレイテッド | 増殖培地を含むカセット |
| FR2945457B1 (fr) * | 2009-05-12 | 2011-07-15 | Aes Chemunex | Ensemble forme d'une membrane de filtration et d'une plaque de support, ainsi que dispositif de test microbiologique en faisant usage. |
| FR2955120B1 (fr) * | 2010-01-14 | 2012-02-10 | Millipore Corp | Procede et outil de transfert de membrane |
| DK2776550T3 (en) * | 2011-11-07 | 2018-02-19 | Rapid Micro Biosystems Inc | Cartridge for sterility testing |
| US10407707B2 (en) * | 2012-04-16 | 2019-09-10 | Rapid Micro Biosystems, Inc. | Cell culturing device |
| EP2769204B1 (en) * | 2012-05-02 | 2016-02-17 | Charles River Laboratories, Inc. | Cell capture system and use thereof |
| CN103045518A (zh) * | 2012-12-31 | 2013-04-17 | 江苏嘉语生物医药技术有限公司 | 一种肺炎支原体的培养与检测方法 |
| GB2517063B (en) * | 2013-06-19 | 2018-02-28 | Brightwake Ltd | Cell collection device |
| CN105874052B (zh) * | 2013-11-04 | 2019-05-21 | 查尔斯河实验室公司 | 过滤系统和其使用 |
| WO2019005809A1 (en) * | 2017-06-30 | 2019-01-03 | Boston Scientific Scimed, Inc. | FILTRATION DEVICES FOR BIOLOGICAL SAMPLES |
| EP3678760A1 (en) * | 2017-09-06 | 2020-07-15 | Merck Patent GmbH | Filtration assembly and method for microbiological testing |
| CN209778864U (zh) * | 2019-04-18 | 2019-12-13 | 李玉乾 | 微生物检测培养装置 |
| CN212688063U (zh) * | 2020-07-21 | 2021-03-12 | 重庆三峡学院 | 微生物培养瓶 |
-
2021
- 2021-07-08 US US18/004,589 patent/US20230257692A1/en active Pending
- 2021-07-08 EP EP21838588.8A patent/EP4179062A4/en active Pending
- 2021-07-08 WO PCT/US2021/040935 patent/WO2022011169A1/en active Application Filing
- 2021-07-08 CA CA3185278A patent/CA3185278A1/en active Pending
- 2021-07-08 CN CN202180054929.0A patent/CN116075586A/zh active Pending
- 2021-07-08 KR KR1020237004483A patent/KR20230035119A/ko unknown
- 2021-07-08 AU AU2021305328A patent/AU2021305328A1/en active Pending
- 2021-07-08 JP JP2023501191A patent/JP2023535296A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20230257692A1 (en) | 2023-08-17 |
| AU2021305328A1 (en) | 2023-02-09 |
| WO2022011169A1 (en) | 2022-01-13 |
| CN116075586A (zh) | 2023-05-05 |
| JP2023535296A (ja) | 2023-08-17 |
| KR20230035119A (ko) | 2023-03-10 |
| EP4179062A1 (en) | 2023-05-17 |
| EP4179062A4 (en) | 2024-06-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11788046B2 (en) | Cassette for sterility testing | |
| US12091703B2 (en) | Cell culturing device | |
| CN107548416B (zh) | 用于多孔板的契合盖子 | |
| US20070212747A1 (en) | Cassette containing growth medium | |
| JP6086728B2 (ja) | 蓋付きディープウェルプレートシステム | |
| WO2001046381A1 (en) | Nano-grid micro reactor and methods | |
| US20140248618A1 (en) | Microfluidic flow cell assemblies and method of use | |
| CN101294135B (zh) | 微生物分析组件和方法 | |
| US20080233015A1 (en) | Device and method for use in analysis | |
| EP1974818A1 (en) | Device and method for use in analysis | |
| CN207845648U (zh) | 用于附接到瓶的适配器组件 | |
| JP6723541B2 (ja) | 撮像用マイクロ流体フローセルアセンブリ及びその使用方法 | |
| KR20220151179A (ko) | 세포 배양 컨테이너 | |
| US20230257692A1 (en) | Filtration assemblies, cassettes, systems, and methods for filtration and cell growth | |
| US7618592B2 (en) | Detachable engageable microarray plate liner | |
| US11261414B2 (en) | Apparatus for reconfiguration of components in a microphysiological system | |
| JP2014008051A (ja) | ろ過分離方法及びこれに使用するろ過分離装置 | |
| US9080941B2 (en) | Microfluidic flow cell assemblies for imaging and method of use |