CA3175067A1 - Aptamers for use in the treatment of coronaviridae infections - Google Patents
Aptamers for use in the treatment of coronaviridae infectionsInfo
- Publication number
- CA3175067A1 CA3175067A1 CA3175067A CA3175067A CA3175067A1 CA 3175067 A1 CA3175067 A1 CA 3175067A1 CA 3175067 A CA3175067 A CA 3175067A CA 3175067 A CA3175067 A CA 3175067A CA 3175067 A1 CA3175067 A1 CA 3175067A1
- Authority
- CA
- Canada
- Prior art keywords
- aptamer
- receptor
- seq
- cov
- virus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/16—Aptamers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20168929 | 2020-04-09 | ||
| EP20168929.6 | 2020-04-09 | ||
| EP20176023 | 2020-05-22 | ||
| EP20176023.8 | 2020-05-22 | ||
| EP20180781.5 | 2020-06-18 | ||
| EP20180781 | 2020-06-18 | ||
| EP20204036 | 2020-10-27 | ||
| EP20204036.6 | 2020-10-27 | ||
| PCT/EP2021/059328 WO2021205012A1 (en) | 2020-04-09 | 2021-04-09 | Aptamers for use in the treatment of coronaviridae infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3175067A1 true CA3175067A1 (en) | 2021-10-14 |
Family
ID=84191962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3175067A Pending CA3175067A1 (en) | 2020-04-09 | 2021-04-09 | Aptamers for use in the treatment of coronaviridae infections |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US12606828B2 (https=) |
| EP (1) | EP4133083A1 (https=) |
| JP (1) | JP2023521361A (https=) |
| KR (1) | KR20220166337A (https=) |
| CN (1) | CN115768895A (https=) |
| AU (1) | AU2021252151A1 (https=) |
| BR (1) | BR112022020439A2 (https=) |
| CA (1) | CA3175067A1 (https=) |
| IL (1) | IL297155A (https=) |
| MX (1) | MX2022012618A (https=) |
| ZA (1) | ZA202212179B (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20230170931A (ko) * | 2021-04-09 | 2023-12-19 | 베를린 큐어스 게엠베하 | 코로나바이러스 감염 치료에 사용하기 위한 압타머 |
| KR102937192B1 (ko) * | 2023-01-25 | 2026-03-17 | 주식회사 리젠시스랩 | 사스 코로나 바이러스 2 특이적 압타머 및 이의 용도 |
| WO2025146959A1 (ko) * | 2024-01-02 | 2025-07-10 | 충북대학교 산학협력단 | ＳＡＲＳＣｏＶ２의 외피 단백질에 특이적으로 결합하는 ＤＮＡ 앱타머 및 이의 용도 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MEP0208A (xx) * | 2005-08-26 | 2010-02-10 | Archemix Corp | Aptameri koji vezuje trombin sa visokim afininitetom |
| EP2497828A1 (en) * | 2011-03-07 | 2012-09-12 | Charité - Universitätsmedizin Berlin | Use of aptamers in therapy and/or diagnosis of autoimmune diseases |
| CN117653654A (zh) * | 2016-11-23 | 2024-03-08 | 柏林制药股份有限公司 | 用于抑制和/或压制tlr9激活的适体 |
-
2021
- 2021-04-09 KR KR1020227039288A patent/KR20220166337A/ko active Pending
- 2021-04-09 CN CN202180041090.7A patent/CN115768895A/zh active Pending
- 2021-04-09 BR BR112022020439A patent/BR112022020439A2/pt unknown
- 2021-04-09 JP JP2022561426A patent/JP2023521361A/ja active Pending
- 2021-04-09 AU AU2021252151A patent/AU2021252151A1/en active Pending
- 2021-04-09 US US17/995,705 patent/US12606828B2/en active Active
- 2021-04-09 EP EP21716761.8A patent/EP4133083A1/en active Pending
- 2021-04-09 MX MX2022012618A patent/MX2022012618A/es unknown
- 2021-04-09 CA CA3175067A patent/CA3175067A1/en active Pending
- 2021-10-14 IL IL297155A patent/IL297155A/en unknown
-
2022
- 2022-11-08 ZA ZA2022/12179A patent/ZA202212179B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20230140490A1 (en) | 2023-05-04 |
| ZA202212179B (en) | 2025-03-26 |
| KR20220166337A (ko) | 2022-12-16 |
| US12606828B2 (en) | 2026-04-21 |
| EP4133083A1 (en) | 2023-02-15 |
| IL297155A (en) | 2022-12-01 |
| JP2023521361A (ja) | 2023-05-24 |
| AU2021252151A1 (en) | 2022-12-08 |
| CN115768895A (zh) | 2023-03-07 |
| BR112022020439A2 (pt) | 2022-11-29 |
| MX2022012618A (es) | 2022-11-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20230331837A1 (en) | Oligonucleotides for reduction of pd-l1 expression | |
| US12606828B2 (en) | Aptamers for use in the treatment of Coronaviridae infections | |
| JP6587934B2 (ja) | Ｐｄｇｆおよびｖｅｇｆ結合アプタマー、および、ｐｄｇｆおよびｖｅｇｆが介在する病気の治療へのそれらの使用 | |
| US10266830B2 (en) | Use of aptamers in therapy and/or diagnosis of autoimmune diseases | |
| KR102242874B1 (ko) | Ｉｌ―６에 결합하는 압타머 및 ｉｌ―６ 매개된 질환을 치료하거나 진단하는 데에서 이의 용도 | |
| JP2026021387A (ja) | コロナウイルス科感染の治療において使用するためのアプタマー | |
| WO2021205012A1 (en) | Aptamers for use in the treatment of coronaviridae infections | |
| HK40104624B (en) | Aptamers for use in the treatment of coronaviridae infections | |
| HK40104624A (en) | Aptamers for use in the treatment of coronaviridae infections | |
| CN117642179A (zh) | 流感病毒核酸脂质颗粒疫苗 | |
| CN121419780A (zh) | 用于抑制甲型流感病毒基因表达的RNAi试剂、其组合物和使用方法 | |
| NZ785334A (en) | Oligonucleotides for reduction of pd-l1 expression | |
| NZ785335A (en) | Oligonucleotides for reduction of pd-l1 expression |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| D11 | Substantive examination requested |
Free format text: ST27 STATUS EVENT CODE: A-1-1-D10-D11-D117 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: REQUEST FOR EXAMINATION RECEIVED Effective date: 20250328 |
|
| W00 | Other event occurred |
Free format text: ST27 STATUS EVENT CODE: A-1-1-W10-W00-W111 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: CORRESPONDENT DETERMINED COMPLIANT Effective date: 20250328 |
|
| MFA | Maintenance fee for application paid |
Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 4TH ANNIV.) - SMALL Year of fee payment: 4 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20250401 |
|
| D00 | Search and/or examination requested or commenced |
Free format text: ST27 STATUS EVENT CODE: A-1-1-D10-D00-D118 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: REQUEST FOR EXAMINATION REQUIREMENTS DETERMINED COMPLIANT Effective date: 20250428 |
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| D11 | Substantive examination requested |
Free format text: ST27 STATUS EVENT CODE: A-1-2-D10-D11-D155 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: ALL REQUIREMENTS FOR EXAMINATION DETERMINED COMPLIANT Effective date: 20250507 |
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| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20250516 |
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| W00 | Other event occurred |
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| MFA | Maintenance fee for application paid |
Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 5TH ANNIV.) - SMALL Year of fee payment: 5 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20260330 |
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| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20260330 |