CA3171025A1 - Fibroblast activation protein ligands for targeted delivery applications - Google Patents
Fibroblast activation protein ligands for targeted delivery applicationsInfo
- Publication number
- CA3171025A1 CA3171025A1 CA3171025A CA3171025A CA3171025A1 CA 3171025 A1 CA3171025 A1 CA 3171025A1 CA 3171025 A CA3171025 A CA 3171025A CA 3171025 A CA3171025 A CA 3171025A CA 3171025 A1 CA3171025 A1 CA 3171025A1
- Authority
- CA
- Canada
- Prior art keywords
- moiety
- cancer
- compound
- conjugate
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/545—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20157036 | 2020-02-12 | ||
| EP20157036.3 | 2020-02-12 | ||
| EP20172953.0 | 2020-05-05 | ||
| EP20172953 | 2020-05-05 | ||
| EP20202856.9 | 2020-10-20 | ||
| EP20202856 | 2020-10-20 | ||
| PCT/EP2021/053494 WO2021160825A1 (en) | 2020-02-12 | 2021-02-12 | Fibroblast activation protein ligands for targeted delivery applications |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3171025A1 true CA3171025A1 (en) | 2021-08-19 |
Family
ID=83225945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3171025A Pending CA3171025A1 (en) | 2020-02-12 | 2021-02-12 | Fibroblast activation protein ligands for targeted delivery applications |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JP2023514275A (ko) |
| KR (1) | KR20220154111A (ko) |
| CN (1) | CN115335370A (ko) |
| AU (1) | AU2021220663A1 (ko) |
| BR (1) | BR112022016049A2 (ko) |
| CA (1) | CA3171025A1 (ko) |
| IL (1) | IL295571A (ko) |
| MX (1) | MX2022009931A (ko) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116925041A (zh) * | 2023-06-12 | 2023-10-24 | 上海交通大学医学院附属仁济医院 | 靶向成纤维细胞激活蛋白的氟标记放射性药物前体、放射性标记化合物及其应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2020006128A (es) * | 2017-12-15 | 2020-09-21 | Praxis Biotech LLC | Inhibidores de la proteina de activacion de fibroblastos. |
| AU2019219057B2 (en) * | 2018-02-06 | 2022-11-24 | Universität Heidelberg | FAP inhibitor |
-
2021
- 2021-02-12 CN CN202180022488.6A patent/CN115335370A/zh active Pending
- 2021-02-12 MX MX2022009931A patent/MX2022009931A/es unknown
- 2021-02-12 AU AU2021220663A patent/AU2021220663A1/en active Pending
- 2021-02-12 IL IL295571A patent/IL295571A/en unknown
- 2021-02-12 KR KR1020227031463A patent/KR20220154111A/ko unknown
- 2021-02-12 CA CA3171025A patent/CA3171025A1/en active Pending
- 2021-02-12 BR BR112022016049A patent/BR112022016049A2/pt unknown
- 2021-02-12 JP JP2022549170A patent/JP2023514275A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20220154111A (ko) | 2022-11-21 |
| AU2021220663A1 (en) | 2022-10-06 |
| JP2023514275A (ja) | 2023-04-05 |
| CN115335370A (zh) | 2022-11-11 |
| BR112022016049A2 (pt) | 2022-11-16 |
| MX2022009931A (es) | 2022-09-12 |
| IL295571A (en) | 2022-10-01 |
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