CA3166728A1 - Engineered leishmania cells - Google Patents
Engineered leishmania cellsInfo
- Publication number
- CA3166728A1 CA3166728A1 CA3166728A CA3166728A CA3166728A1 CA 3166728 A1 CA3166728 A1 CA 3166728A1 CA 3166728 A CA3166728 A CA 3166728A CA 3166728 A CA3166728 A CA 3166728A CA 3166728 A1 CA3166728 A1 CA 3166728A1
- Authority
- CA
- Canada
- Prior art keywords
- nucleotides
- homologous
- dna fragments
- homologous region
- leishmania
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/10—Protozoa; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062958088P | 2020-01-07 | 2020-01-07 | |
| US62/958,088 | 2020-01-07 | ||
| PCT/EP2021/050173 WO2021140144A1 (en) | 2020-01-07 | 2021-01-07 | Engineered leishmania cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3166728A1 true CA3166728A1 (en) | 2021-07-15 |
Family
ID=74194706
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3166728A Pending CA3166728A1 (en) | 2020-01-07 | 2021-01-07 | Engineered leishmania cells |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20230048847A1 (https=) |
| EP (1) | EP4087912A1 (https=) |
| JP (1) | JP7720307B2 (https=) |
| AU (1) | AU2021206008A1 (https=) |
| CA (1) | CA3166728A1 (https=) |
| WO (1) | WO2021140144A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20240145084A (ko) | 2017-06-30 | 2024-10-04 | 림마테크 바이오로직스 아게 | 조작되고 완전-기능 맞춤 당단백질 |
| JP2024513755A (ja) | 2021-03-23 | 2024-03-27 | グリコエラ アーゲー | マンノース３グリカン媒介タンパク質分解 |
| WO2022200390A2 (en) | 2021-03-23 | 2022-09-29 | Glycoera Ag | Glycan-mediated protein degradation |
| WO2024068753A1 (en) | 2022-09-28 | 2024-04-04 | Glycoera Ag | Glycan-mediated protein degradation |
| US20260055211A1 (en) | 2023-01-05 | 2026-02-26 | Glycoera Ag | Glycoengineered polypeptides targeting anti-neutrophil autoantibodies and uses thereof |
| WO2024147113A1 (en) | 2023-01-05 | 2024-07-11 | Glycoera Ag | Glycoengineered polypeptides targeting anti-podocyte autoantibodies and uses thereof |
| JP2026501773A (ja) | 2023-01-05 | 2026-01-16 | グリコエラ アーゲー | 免疫グロブリンａを標的とする糖鎖改変ポリペプチド及びそれを含む複合体 |
| WO2024218743A1 (en) | 2023-04-21 | 2024-10-24 | Glycoera Ag | Multi-functional molecules comprising glycans and uses thereof |
| WO2025215516A1 (en) | 2024-04-08 | 2025-10-16 | Glycoera Ag | Glycoengineered polypeptides targeting igg4 autoantibodies and uses thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69133557D1 (de) * | 1990-08-29 | 2007-03-15 | Pharming Intellectual Pty Bv | Homologe rekombination in säugetier-zellen |
| US7351578B2 (en) * | 1999-12-10 | 2008-04-01 | Invitrogen Corp. | Use of multiple recombination sites with unique specificity in recombinational cloning |
| US20010010928A1 (en) * | 1999-03-26 | 2001-08-02 | Stephen M. Beverley | Protozoan expression system |
| WO2001032896A1 (en) * | 1999-11-05 | 2001-05-10 | Jena Bioscience Gmbh | Protein expression systems for non-pathogenic <i>kinetoplastidae</i> |
| WO2002090556A1 (en) * | 2001-05-08 | 2002-11-14 | Jena Bioscience Gmbh | Method for targeted homologous gene replacement in kinetoplastidae |
| KR20140048929A (ko) * | 2011-06-21 | 2014-04-24 | 에비아제닉스 에스.에이. | 물질대사적 발달의 방법 |
| US11293033B2 (en) * | 2016-05-18 | 2022-04-05 | Amyris, Inc. | Compositions and methods for genomic integration of nucleic acids into exogenous landing pads |
| KR20240145084A (ko) | 2017-06-30 | 2024-10-04 | 림마테크 바이오로직스 아게 | 조작되고 완전-기능 맞춤 당단백질 |
| WO2019234021A1 (en) * | 2018-06-04 | 2019-12-12 | Limmatech Biologics Ag | Glycoengineered monoclonal antibody |
-
2021
- 2021-01-07 WO PCT/EP2021/050173 patent/WO2021140144A1/en not_active Ceased
- 2021-01-07 CA CA3166728A patent/CA3166728A1/en active Pending
- 2021-01-07 AU AU2021206008A patent/AU2021206008A1/en active Pending
- 2021-01-07 US US17/791,085 patent/US20230048847A1/en active Pending
- 2021-01-07 EP EP21701048.7A patent/EP4087912A1/en active Pending
- 2021-01-07 JP JP2022541861A patent/JP7720307B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20230048847A1 (en) | 2023-02-16 |
| EP4087912A1 (en) | 2022-11-16 |
| JP7720307B2 (ja) | 2025-08-07 |
| AU2021206008A1 (en) | 2022-07-28 |
| WO2021140144A1 (en) | 2021-07-15 |
| JP2023509734A (ja) | 2023-03-09 |
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