CA3136405A1 - Detection method for cancer using rna biomarkers - Google Patents

Detection method for cancer using rna biomarkers Download PDF

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Publication number
CA3136405A1
CA3136405A1 CA3136405A CA3136405A CA3136405A1 CA 3136405 A1 CA3136405 A1 CA 3136405A1 CA 3136405 A CA3136405 A CA 3136405A CA 3136405 A CA3136405 A CA 3136405A CA 3136405 A1 CA3136405 A1 CA 3136405A1
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CA
Canada
Prior art keywords
stool
subject
colorectal
rna
biomarkers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3136405A
Other languages
English (en)
French (fr)
Inventor
Andrew BARNELL
Erica BARNELL
Yiming KANG
Elizabeth WURTZLER
Katie CAMPBELL
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Geneoscopy Inc
Original Assignee
Geneoscopy Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geneoscopy Inc filed Critical Geneoscopy Inc
Publication of CA3136405A1 publication Critical patent/CA3136405A1/en
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57535—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the large intestine, e.g. colon, rectum or anus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CA3136405A 2018-06-01 2019-05-31 Detection method for cancer using rna biomarkers Pending CA3136405A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862679621P 2018-06-01 2018-06-01
US62/679,621 2018-06-01
US201962797763P 2019-01-28 2019-01-28
US62/797,763 2019-01-28
PCT/US2019/035061 WO2019232483A1 (en) 2018-06-01 2019-05-31 Detection method

Publications (1)

Publication Number Publication Date
CA3136405A1 true CA3136405A1 (en) 2019-12-05

Family

ID=68698469

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3136405A Pending CA3136405A1 (en) 2018-06-01 2019-05-31 Detection method for cancer using rna biomarkers

Country Status (8)

Country Link
US (3) US20210214797A1 (https=)
EP (1) EP3802885A4 (https=)
JP (1) JP7650663B2 (https=)
CN (1) CN112567050A (https=)
AU (1) AU2019276577B2 (https=)
CA (1) CA3136405A1 (https=)
IL (1) IL279125B2 (https=)
WO (1) WO2019232483A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2986412T3 (es) 2016-10-27 2024-11-11 Geneoscopy Inc Método de aislamiento de ácidos nucleicos eucariotas a partir de muestras de heces
EP4426860A4 (en) * 2021-11-01 2025-11-12 Univ Colorado State Res Found DIRECT NON-INVASIVE PROTEOMIC PROFILING USING STOOL SAMPLES FOR THE DIAGNOSIS OF GASTROINTESTINAL DISEASES
KR102425034B1 (ko) * 2021-12-14 2022-07-27 주식회사 에이아이더뉴트리진 표적 바이러스 검출을 위한 페이퍼 멤브레인 기반 현장용 rna 추출 플랫폼
CN115602326A (zh) * 2022-10-21 2023-01-13 中国科学院计算技术研究所（Cn） 一种用于挖掘肿瘤标志物的方法以及肿瘤风险筛查方法
WO2024108271A1 (en) * 2022-11-25 2024-05-30 Denis King Colorectal cancer risk assessment
EP4654960A1 (en) * 2023-01-26 2025-12-03 Mayo Foundation for Medical Education and Research Assessing and treating mammals having polyps
US20260060660A1 (en) 2024-08-30 2026-03-05 Geneoscopy, Inc. Compositions and methods for immunological testing of stool

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4033820B2 (ja) 2003-07-29 2008-01-16 株式会社日立製作所 細胞回収方法
JP2007175021A (ja) 2005-12-28 2007-07-12 Sysmex Corp 大腸がんのリンパ節転移マーカー
EP1862803A1 (en) 2006-06-02 2007-12-05 Atlas Antibodies AB Use of protein SATB2 as a marker for colorectal cancer
WO2007149269A2 (en) 2006-06-12 2007-12-27 Oncomethylome Sciences S.A. Methylation markers for early detection and prognosis of colon cancers
US20100196889A1 (en) * 2006-11-13 2010-08-05 Bankaitis-Davis Danute M Gene Expression Profiling for Identification, Monitoring and Treatment of Colorectal Cancer
GB0700374D0 (en) * 2007-01-09 2007-02-14 Oncomethylome Sciences S A NDRG family methylation markers
JPWO2008093530A1 (ja) 2007-01-30 2010-05-20 国立大学法人浜松医科大学 大腸癌病期検出方法
FR2919062B1 (fr) * 2007-07-19 2009-10-02 Biomerieux Sa Procede de dosage de l'aminoacylase 1 pour le diagnostic in vitro du cancer colorectal.
WO2009042676A1 (en) 2007-09-24 2009-04-02 University Of South Florida Method for early detection of cancers
EP2287331A4 (en) 2008-05-12 2012-01-25 Olympus Corp PROCESS FOR PROCESSING EXCREMENTS AND CONTAINERS FOR PROCESSING EXCREMENTS
CN102105583A (zh) 2008-07-23 2011-06-22 奥林巴斯株式会社 从粪便试样中回收核酸的方法、核酸分析方法以及粪便试样处理装置
WO2010042903A1 (en) 2008-10-09 2010-04-15 Alfagene Bioscience, Inc Use and identification of biomarkers for gastrointestinal diseases
WO2010053539A2 (en) * 2008-11-05 2010-05-14 The Texas A&M University System Methods for detecting colorectal diseases and disorders
JPWO2010134246A1 (ja) 2009-05-20 2012-11-08 オリンパス株式会社 核酸含有試料の調製方法
JPWO2010134245A1 (ja) 2009-05-20 2012-11-08 オリンパス株式会社 哺乳細胞由来核酸の回収方法、核酸解析方法、及び採便用キット
EP2655661B1 (en) * 2010-12-23 2015-03-11 Agendia N.V. Methods and means for molecular classification of colorectal cancers
AU2012301589A1 (en) * 2011-08-31 2014-02-27 Oncocyte Corporation Methods and compositions for the treatment and diagnosis of colorectal cancer
KR102175688B1 (ko) 2013-03-27 2020-11-06 제넨테크, 인크. 베타7 인테그린 길항제를 사용하는 위장 염증성 장애의 치료를 평가하기 위한 바이오마커의 사용
CN103324846A (zh) * 2013-06-13 2013-09-25 浙江加州国际纳米技术研究院绍兴分院 结直肠癌症治疗预后生物标记物的筛选方法
US11035006B2 (en) 2013-07-30 2021-06-15 H. Lee Moffitt Cancer Center And Research Institute, Inc. Colorectal cancer recurrence gene expression signature
US20180282815A1 (en) 2015-04-29 2018-10-04 Geneoscopy, Llc Colorectal cancer screening method and device
GB201513921D0 (en) * 2015-08-05 2015-09-23 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers
ES2986412T3 (es) * 2016-10-27 2024-11-11 Geneoscopy Inc Método de aislamiento de ácidos nucleicos eucariotas a partir de muestras de heces

Also Published As

Publication number Publication date
AU2019276577B2 (en) 2025-09-11
IL279125B1 (en) 2025-11-01
JP2021526375A (ja) 2021-10-07
AU2019276577A1 (en) 2021-01-14
CN112567050A (zh) 2021-03-26
EP3802885A1 (en) 2021-04-14
WO2019232483A1 (en) 2019-12-05
IL279125B2 (en) 2026-03-01
US20220154291A1 (en) 2022-05-19
EP3802885A4 (en) 2022-03-02
JP7650663B2 (ja) 2025-03-25
US20240093312A1 (en) 2024-03-21
US20210214797A1 (en) 2021-07-15
IL279125A (en) 2021-01-31
US11479824B2 (en) 2022-10-25

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