CA3136229A1 - Novel psma specific binding proteins for cancer diagnosis and treatment - Google Patents

Novel psma specific binding proteins for cancer diagnosis and treatment Download PDF

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Publication number
CA3136229A1
CA3136229A1 CA3136229A CA3136229A CA3136229A1 CA 3136229 A1 CA3136229 A1 CA 3136229A1 CA 3136229 A CA3136229 A CA 3136229A CA 3136229 A CA3136229 A CA 3136229A CA 3136229 A1 CA3136229 A1 CA 3136229A1
Authority
CA
Canada
Prior art keywords
psma
binding protein
seq
psma binding
ubiquitin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3136229A
Other languages
English (en)
French (fr)
Inventor
Eva BOSSE-DOENECKE
Manja Gloser-Braunig
Florian SETTELE
Erik Fiedler
Ulrich Haupts
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Navigo Proteins GmbH
Original Assignee
Navigo Proteins GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Navigo Proteins GmbH filed Critical Navigo Proteins GmbH
Publication of CA3136229A1 publication Critical patent/CA3136229A1/en
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA3136229A 2019-04-10 2020-04-08 Novel psma specific binding proteins for cancer diagnosis and treatment Pending CA3136229A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19168525.4 2019-04-10
EP19168525 2019-04-10
PCT/EP2020/060043 WO2020208083A1 (en) 2019-04-10 2020-04-08 Novel psma specific binding proteins for cancer diagnosis and treatment

Publications (1)

Publication Number Publication Date
CA3136229A1 true CA3136229A1 (en) 2020-10-15

Family

ID=66286079

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3136229A Pending CA3136229A1 (en) 2019-04-10 2020-04-08 Novel psma specific binding proteins for cancer diagnosis and treatment

Country Status (12)

Country Link
US (1) US12611441B2 (https=)
EP (2) EP3953375B9 (https=)
JP (1) JP7498971B2 (https=)
KR (1) KR102934740B1 (https=)
CN (1) CN113677698B (https=)
AU (1) AU2020271959B2 (https=)
BR (1) BR112021017863A2 (https=)
CA (1) CA3136229A1 (https=)
IL (1) IL286791A (https=)
SG (1) SG11202110940YA (https=)
WO (1) WO2020208083A1 (https=)
ZA (1) ZA202108843B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023285164A1 (en) * 2021-07-13 2023-01-19 Navigo Proteins Gmbh Affinity ligands for the purification and detection of ubiquitin muteins
CN114569744A (zh) * 2022-03-08 2022-06-03 安徽淮仁堂药业股份有限公司 一种锝前列腺标特异性膜抗原显像剂试剂盒及其制备方法和应用
CN116041435B (zh) * 2023-02-21 2023-07-07 浙江农林大学 一种具有2019新型冠状病毒主蛋白酶抑制活性的榛仁蛋白衍生肽及其应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003035839A2 (en) * 2001-10-24 2003-05-01 Dgi Biotechnologies, Inc. Target specific screening andits use for identifying target binders
WO2006028429A2 (en) 2002-08-05 2006-03-16 The Johns Hopkins University Peptides for targeting the prostate specific membrane antigen
DE10324447A1 (de) * 2003-05-28 2004-12-30 Scil Proteins Gmbh Generierung künstlicher Bindungsproteine auf der Grundlage von Ubiquitin
RU2553333C2 (ru) * 2009-12-14 2015-06-10 Сцил Протеинс Гмбх Способ идентификации гетеромультимерных модифицированных убиквитиновых белков со способностью связываться с лигандами
WO2012171541A1 (en) * 2011-06-15 2012-12-20 Scil Proteins Gmbh Human fusion proteins comprising interferons and hetero-dimeric modified ubiquitin proteins
JP6738340B2 (ja) * 2015-02-06 2020-08-12 ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツングNavigo Proteins GmbH 新規なegfr結合タンパク質
WO2016124670A1 (en) * 2015-02-06 2016-08-11 Scil Proteins Gmbh Novel binding proteins comprising a ubiquitin mutein and antibodies or antibody fragments
US10844111B2 (en) * 2015-05-06 2020-11-24 Janssen Biotech, Inc. Prostate specific membrane antigen binding fibronectin type III domains
WO2017013136A1 (en) * 2015-07-20 2017-01-26 Scil Proteins Gmbh Novel binding proteins based on di-ubiquitin muteins and methods for generation
DK3325514T3 (da) * 2015-07-20 2019-12-16 Navigo Proteins Gmbh Her2-bindende proteiner baseret på di-ubiquitin-muteiner
WO2017149002A1 (en) 2016-03-03 2017-09-08 Navigo Proteins Gmbh Novel fusion proteins for capturing of cells
WO2023285164A1 (en) * 2021-07-13 2023-01-19 Navigo Proteins Gmbh Affinity ligands for the purification and detection of ubiquitin muteins

Also Published As

Publication number Publication date
IL286791A (en) 2021-10-31
AU2020271959B2 (en) 2022-09-29
EP4108680A1 (en) 2022-12-28
EP4108680B1 (en) 2024-05-01
EP3953375A1 (en) 2022-02-16
KR102934740B1 (ko) 2026-03-04
US12611441B2 (en) 2026-04-28
WO2020208083A1 (en) 2020-10-15
ZA202108843B (en) 2023-07-26
EP3953375B9 (en) 2023-10-04
EP4108680C0 (en) 2024-05-01
JP2022528053A (ja) 2022-06-08
CN113677698A (zh) 2021-11-19
CN113677698B (zh) 2025-02-25
JP7498971B2 (ja) 2024-06-13
SG11202110940YA (en) 2021-10-28
AU2020271959A1 (en) 2021-09-16
US20220168386A1 (en) 2022-06-02
EP3953375C0 (en) 2023-06-07
EP3953375B1 (en) 2023-06-07
KR20210150535A (ko) 2021-12-10
BR112021017863A2 (pt) 2022-01-04

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