CA3125383A1 - Analogues peptidiques de conotoxine et leurs utilisations pour le traitement de la douleur et d'affections inflammatoires - Google Patents
Analogues peptidiques de conotoxine et leurs utilisations pour le traitement de la douleur et d'affections inflammatoires Download PDFInfo
- Publication number
- CA3125383A1 CA3125383A1 CA3125383A CA3125383A CA3125383A1 CA 3125383 A1 CA3125383 A1 CA 3125383A1 CA 3125383 A CA3125383 A CA 3125383A CA 3125383 A CA3125383 A CA 3125383A CA 3125383 A1 CA3125383 A1 CA 3125383A1
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- CA
- Canada
- Prior art keywords
- peptide analog
- conotoxin peptide
- pharmaceutically acceptable
- acceptable salt
- pegylated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Abstract
La présente invention concerne des analogues peptidiques d'alpha-conotoxine, notamment des analogues peptidiques d'alpha-conotoxine qui sont liés de manière covalente au polyéthylène glycol (PEG), et des compositions pharmaceutiques de tels analogues peptidiques d'alpha-conotoxine. L'invention concerne également des méthodes de traitement ou de prévention d'une affection favorable au traitement ou à la prévention par inhibition d'un récepteur nicotinique de l'acétylcholine (nAChR) contenant a9 (par exemple, le sous-type a9a10 du nAChR) chez un sujet.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2019/012307 WO2020142102A1 (fr) | 2019-01-04 | 2019-01-04 | Analogues peptidiques de conotoxine et leurs utilisations pour le traitement de la douleur et d'affections inflammatoires |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3125383A1 true CA3125383A1 (fr) | 2020-07-09 |
Family
ID=65244618
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3125383A Pending CA3125383A1 (fr) | 2019-01-04 | 2019-01-04 | Analogues peptidiques de conotoxine et leurs utilisations pour le traitement de la douleur et d'affections inflammatoires |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP3906253A1 (fr) |
| JP (1) | JP2022522935A (fr) |
| KR (1) | KR20210116505A (fr) |
| CN (1) | CN113966339A (fr) |
| AU (1) | AU2019418319A1 (fr) |
| BR (1) | BR112021013302A2 (fr) |
| CA (1) | CA3125383A1 (fr) |
| CL (1) | CL2021001775A1 (fr) |
| CO (1) | CO2021008845A2 (fr) |
| CR (1) | CR20210363A (fr) |
| IL (1) | IL284574A (fr) |
| MX (1) | MX2021008070A (fr) |
| PE (1) | PE20211734A1 (fr) |
| SG (1) | SG11202106847SA (fr) |
| WO (1) | WO2020142102A1 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20230033485A (ko) | 2021-09-01 | 2023-03-08 | 삼성전자주식회사 | 저장 장치 및 그의 동작 방법 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2051726B1 (fr) | 2006-07-18 | 2018-04-18 | University of Utah Research Foundation | Procédé pour traiter la douleur et rechercher systématiquement des composés analgésiques |
| US9284358B2 (en) * | 2006-07-18 | 2016-03-15 | University Of Utah Research Foundation | Conotoxin peptides |
| WO2009126292A2 (fr) * | 2008-04-08 | 2009-10-15 | Aileron Therapeutics, Inc. | Macrocycles peptidomimétiques biologiquement actifs |
| CN102875654B (zh) * | 2012-09-25 | 2014-07-09 | 中国人民解放军军事医学科学院生物工程研究所 | 芋螺毒素多肽Eb1.6的制备方法 |
| PL2970389T3 (pl) * | 2013-03-15 | 2021-03-08 | Rhythm Pharmaceuticals, Inc. | Kompozycje farmaceutyczne |
| WO2016073949A1 (fr) * | 2014-11-07 | 2016-05-12 | Kineta Three, Llp | Modifications et utilisations de peptides de conotoxine |
-
2019
- 2019-01-04 MX MX2021008070A patent/MX2021008070A/es unknown
- 2019-01-04 EP EP19702500.0A patent/EP3906253A1/fr not_active Withdrawn
- 2019-01-04 WO PCT/US2019/012307 patent/WO2020142102A1/fr unknown
- 2019-01-04 PE PE2021001115A patent/PE20211734A1/es unknown
- 2019-01-04 SG SG11202106847SA patent/SG11202106847SA/en unknown
- 2019-01-04 CR CR20210363A patent/CR20210363A/es unknown
- 2019-01-04 CA CA3125383A patent/CA3125383A1/fr active Pending
- 2019-01-04 CN CN201980093540.XA patent/CN113966339A/zh active Pending
- 2019-01-04 BR BR112021013302-0A patent/BR112021013302A2/pt unknown
- 2019-01-04 AU AU2019418319A patent/AU2019418319A1/en active Pending
- 2019-01-04 JP JP2021538994A patent/JP2022522935A/ja active Pending
- 2019-01-04 KR KR1020217024613A patent/KR20210116505A/ko not_active Application Discontinuation
-
2021
- 2021-07-02 CL CL2021001775A patent/CL2021001775A1/es unknown
- 2021-07-02 IL IL284574A patent/IL284574A/en unknown
- 2021-07-02 CO CONC2021/0008845A patent/CO2021008845A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CR20210363A (es) | 2021-12-10 |
| WO2020142102A9 (fr) | 2020-11-19 |
| KR20210116505A (ko) | 2021-09-27 |
| PE20211734A1 (es) | 2021-09-06 |
| CN113966339A (zh) | 2022-01-21 |
| AU2019418319A1 (en) | 2021-07-22 |
| MX2021008070A (es) | 2021-10-13 |
| SG11202106847SA (en) | 2021-07-29 |
| IL284574A (en) | 2021-08-31 |
| EP3906253A1 (fr) | 2021-11-10 |
| BR112021013302A2 (pt) | 2021-09-14 |
| CO2021008845A2 (es) | 2021-10-29 |
| WO2020142102A1 (fr) | 2020-07-09 |
| JP2022522935A (ja) | 2022-04-21 |
| CL2021001775A1 (es) | 2022-05-27 |
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| EEER | Examination request |
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