CA3112234A1 - Pharmaceutical compositions suitable for articular delivery and use thereof in treatment of joint pain - Google Patents
Pharmaceutical compositions suitable for articular delivery and use thereof in treatment of joint pain Download PDFInfo
- Publication number
- CA3112234A1 CA3112234A1 CA3112234A CA3112234A CA3112234A1 CA 3112234 A1 CA3112234 A1 CA 3112234A1 CA 3112234 A CA3112234 A CA 3112234A CA 3112234 A CA3112234 A CA 3112234A CA 3112234 A1 CA3112234 A1 CA 3112234A1
- Authority
- CA
- Canada
- Prior art keywords
- pharmaceutical composition
- tmol
- per
- phospholipids
- amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Rheumatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Physical Education & Sports Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862731941P | 2018-09-16 | 2018-09-16 | |
| US62/731,941 | 2018-09-16 | ||
| PCT/US2019/051247 WO2020056399A1 (en) | 2018-09-16 | 2019-09-16 | Pharmaceutical compositions suitable for articular delivery and use thereof in treatment of joint pain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3112234A1 true CA3112234A1 (en) | 2020-03-19 |
Family
ID=68084954
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3112234A Pending CA3112234A1 (en) | 2018-09-16 | 2019-09-16 | Pharmaceutical compositions suitable for articular delivery and use thereof in treatment of joint pain |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US12208104B2 (enExample) |
| EP (1) | EP3849522A1 (enExample) |
| JP (1) | JP7634476B2 (enExample) |
| KR (1) | KR20210060559A (enExample) |
| CN (1) | CN112702993A (enExample) |
| AU (1) | AU2019339528B2 (enExample) |
| BR (1) | BR112021004880A2 (enExample) |
| CA (1) | CA3112234A1 (enExample) |
| CL (1) | CL2021000627A1 (enExample) |
| IL (1) | IL281513B1 (enExample) |
| MX (1) | MX2021003030A (enExample) |
| SG (1) | SG11202102400PA (enExample) |
| TW (1) | TWI843751B (enExample) |
| WO (1) | WO2020056399A1 (enExample) |
| ZA (1) | ZA202101688B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023537474A (ja) | 2020-08-05 | 2023-09-01 | ティーエルシー バイオファーマシューティカルズ、インク． | 疼痛制御のための関節内コルチコステロイドの医薬組成物 |
| EP4706666A1 (en) * | 2023-05-05 | 2026-03-11 | Xiangya Hospital, Central South University | Use of magnesium hydroxide in preparation of drug for treating arthralgia |
| IL327816A (en) * | 2023-11-03 | 2026-06-01 | Taiwan Liposome Co Ltd | Liposomal composition of intra-articular corticosteroid for pain control |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050152962A1 (en) * | 2002-06-12 | 2005-07-14 | Metselaar Josbert M. | Composition for treatment of inflammatory disorders |
| EP1371362A1 (en) * | 2002-06-12 | 2003-12-17 | Universiteit Utrecht Holding B.V. | Composition for treatment of inflammatory disorders |
| AU2013216861B2 (en) | 2012-02-10 | 2017-05-18 | Tlc Biopharmaceuticals, Inc | Pharmaceutical compositions to reduce complications of ocular steroid |
| BR112015000174A2 (pt) * | 2012-07-05 | 2017-06-27 | Taiwan Liposome Co Ltd | método para o tratamento da artrite |
-
2019
- 2019-09-16 IL IL281513A patent/IL281513B1/en unknown
- 2019-09-16 AU AU2019339528A patent/AU2019339528B2/en active Active
- 2019-09-16 WO PCT/US2019/051247 patent/WO2020056399A1/en not_active Ceased
- 2019-09-16 BR BR112021004880-4A patent/BR112021004880A2/pt unknown
- 2019-09-16 SG SG11202102400PA patent/SG11202102400PA/en unknown
- 2019-09-16 MX MX2021003030A patent/MX2021003030A/es unknown
- 2019-09-16 JP JP2021511641A patent/JP7634476B2/ja active Active
- 2019-09-16 CA CA3112234A patent/CA3112234A1/en active Pending
- 2019-09-16 CN CN201980059773.8A patent/CN112702993A/zh active Pending
- 2019-09-16 EP EP19779658.4A patent/EP3849522A1/en active Pending
- 2019-09-16 US US17/272,387 patent/US12208104B2/en active Active
- 2019-09-16 TW TW108133237A patent/TWI843751B/zh active
- 2019-09-16 KR KR1020217011328A patent/KR20210060559A/ko not_active Ceased
-
2021
- 2021-03-12 ZA ZA2021/01688A patent/ZA202101688B/en unknown
- 2021-03-15 CL CL2021000627A patent/CL2021000627A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL281513B1 (en) | 2026-07-01 |
| IL281513A (en) | 2021-04-29 |
| AU2019339528A1 (en) | 2021-04-15 |
| AU2019339528B2 (en) | 2025-01-30 |
| ZA202101688B (en) | 2024-06-26 |
| TW202023569A (zh) | 2020-07-01 |
| WO2020056399A1 (en) | 2020-03-19 |
| EP3849522A1 (en) | 2021-07-21 |
| TWI843751B (zh) | 2024-06-01 |
| KR20210060559A (ko) | 2021-05-26 |
| US12208104B2 (en) | 2025-01-28 |
| US20210338688A1 (en) | 2021-11-04 |
| CN112702993A (zh) | 2021-04-23 |
| JP2022500364A (ja) | 2022-01-04 |
| SG11202102400PA (en) | 2021-04-29 |
| MX2021003030A (es) | 2021-05-27 |
| BR112021004880A2 (pt) | 2021-06-01 |
| JP7634476B2 (ja) | 2025-02-21 |
| CL2021000627A1 (es) | 2021-09-10 |
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| JP6609286B2 (ja) | ヒトにおける炎症性障害の治療用リポソームコルチコステロイド | |
| US12208104B2 (en) | Pharmaceutical compositions suitable for articular delivery and use thereof in treatment of joint pain | |
| AU2019301542B2 (en) | Methods to reduce complications of intra-articular steroid | |
| RU2810788C2 (ru) | Фармацевтические композиции, подходящие для суставной доставки, и их применение при лечении суставной боли | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20220815 |
|
| P11 | Amendment of application requested |
Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-P100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: AMENDMENT RECEIVED - RESPONSE TO EXAMINER'S REQUISITION Effective date: 20240805 |
|
| P11 | Amendment of application requested |
Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-P100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: AMENDMENT RECEIVED - RESPONSE TO EXAMINER'S REQUISITION Effective date: 20240816 |
|
| MFA | Maintenance fee for application paid |
Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 5TH ANNIV.) - STANDARD Year of fee payment: 5 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20240904 |
|
| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT DETERMINED COMPLIANT Effective date: 20240904 Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20240904 |
|
| W00 | Other event occurred |
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| P11 | Amendment of application requested |
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|
| W00 | Other event occurred |
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|
| P13 | Application amended |
Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P13-X000 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: APPLICATION AMENDED Effective date: 20250409 |
|
| MFA | Maintenance fee for application paid |
Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 6TH ANNIV.) - STANDARD Year of fee payment: 6 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20250908 |
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| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20250908 |
|
| D15 | Examination report completed |
Free format text: ST27 STATUS EVENT CODE: A-2-2-D10-D15-D126 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: EXAMINER'S REPORT Effective date: 20251114 |
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| P11 | Amendment of application requested |
Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-P100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: AMENDMENT RECEIVED - RESPONSE TO EXAMINER'S REQUISITION Effective date: 20260130 |
|
| P11 | Amendment of application requested |
Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-P102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: AMENDMENT DETERMINED COMPLIANT Effective date: 20260203 |
|
| P13 | Application amended |
Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P13-X000 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: APPLICATION AMENDED Effective date: 20260203 |
|
| W00 | Other event occurred |
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