CA3110652A1 - Methods of using a phenoxypropylamine compound to treat pain - Google Patents

Methods of using a phenoxypropylamine compound to treat pain Download PDF

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Publication number
CA3110652A1
CA3110652A1 CA3110652A CA3110652A CA3110652A1 CA 3110652 A1 CA3110652 A1 CA 3110652A1 CA 3110652 A CA3110652 A CA 3110652A CA 3110652 A CA3110652 A CA 3110652A CA 3110652 A1 CA3110652 A1 CA 3110652A1
Authority
CA
Canada
Prior art keywords
pain
compound
subject
pharmaceutically acceptable
solvate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3110652A
Other languages
English (en)
French (fr)
Inventor
Remy LUTHRINGER
Nadine Noel
Jay SAOUD
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Minerva Neurosciences Inc
Original Assignee
Minerva Neurosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Minerva Neurosciences Inc filed Critical Minerva Neurosciences Inc
Publication of CA3110652A1 publication Critical patent/CA3110652A1/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA3110652A 2018-09-04 2019-09-04 Methods of using a phenoxypropylamine compound to treat pain Pending CA3110652A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862726800P 2018-09-04 2018-09-04
US62/726,800 2018-09-04
PCT/US2019/049492 WO2020101790A2 (en) 2018-09-04 2019-09-04 Methods of using a phenoxypropylamine compound to treat pain

Publications (1)

Publication Number Publication Date
CA3110652A1 true CA3110652A1 (en) 2020-05-22

Family

ID=69641874

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3110652A Pending CA3110652A1 (en) 2018-09-04 2019-09-04 Methods of using a phenoxypropylamine compound to treat pain

Country Status (15)

Country Link
US (2) US11766430B2 (https=)
EP (1) EP3846812A2 (https=)
JP (2) JP7439096B2 (https=)
KR (1) KR102886521B1 (https=)
CN (1) CN112955145A (https=)
AU (2) AU2019381269B2 (https=)
BR (1) BR112021004030A2 (https=)
CA (1) CA3110652A1 (https=)
CL (1) CL2021000531A1 (https=)
GB (1) GB2591937B (https=)
IL (1) IL281166B2 (https=)
MA (1) MA53565A (https=)
MX (1) MX2021002590A (https=)
UA (1) UA129837C2 (https=)
WO (1) WO2020101790A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021026480A2 (pt) 2019-06-28 2022-02-08 Univ Texas Método para reconstituir anamicina, método para preparar uma dose eficaz de uma formulação lipossômica reconstituída de anamicina e método para tratar câncer
JP2024520463A (ja) 2021-05-24 2024-05-24 メディコン ファーマシューティカルズ,インコーポレイテッド 化学療法誘発性末梢神経障害に関連する疼痛の処置
EP4272826A3 (en) * 2021-05-24 2024-01-17 Medicon Pharmaceuticals, Inc. Treating pain associated with diabetic peripheral neuropathy

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4207343A (en) 1978-06-22 1980-06-10 Eli Lilly And Company 1-Phenyl-3-(substituted phenoxy)propylamines
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
ES2244438T3 (es) * 1999-05-24 2005-12-16 Mitsubishi Pharma Corporation Compuestos de fenoxipropilamina.
ES2220582T3 (es) 1999-12-20 2004-12-16 Eli Lilly And Company Derivados de piperidina y su uso como antagonistas de receptor de serotonina.
ATE409475T1 (de) * 2001-02-20 2008-10-15 Dinan Timothy Gerard Behandlung von fibromyalgie mit pindolol
DK1423168T3 (da) * 2001-09-03 2006-05-15 Newron Pharm Spa Farmaceutisk præparat omfattende gabapentin eller en analog deraf og et alfa-aminoamid og dets analgetiske anvendelse
US20040147581A1 (en) 2002-11-18 2004-07-29 Pharmacia Corporation Method of using a Cox-2 inhibitor and a 5-HT1A receptor modulator as a combination therapy
US8716231B2 (en) 2005-12-19 2014-05-06 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain
SA08280759B1 (ar) 2007-01-10 2011-05-04 سولفاي فارماسوتيكالز بي . في مركبات من عوامل مضادة لشبيه القنب – cb1 ومكونات هيكلية من مثبطات إعادة إمتصاص السيروتونين بأندلابين أو فلوكسامين
TW201039815A (en) 2009-04-13 2010-11-16 Resolvyx Pharmaceuticals Inc Compositions and methods for the treatment of inflammation
RU2424799C1 (ru) 2010-03-29 2011-07-27 Государственное образовательное учреждение высшего профессионального образования "БАШКИРСКИЙ ГОСУДАРСТВЕННЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ФЕДЕРАЛЬНОГО АГЕНТСТВА ПО ЗДРАВООХРАНЕНИЮ И СОЦИАЛЬНОМУ РАЗВИТИЮ" Способ коррекции депрессивных расстройств производными тиетан-1,1-диоксида в эксперименте
DK2948143T3 (da) 2013-01-24 2021-07-26 Minerva Neurosciences Inc Anvendelse af phenoxypropylaminforbindelser til behandling af depression
WO2017205399A1 (en) * 2016-05-25 2017-11-30 Minerva Neurosciences, Inc. (2s)-1-[4-(3,4-dichlorophenyl)piperidin-l-yl]-3-[2-(5-methyl-l,3,4-oxadiazol-2-yl)benzo[b]furan-4-yloxy]propan-2-ol or its metabolite for treating anxiety disorders

Also Published As

Publication number Publication date
US11766430B2 (en) 2023-09-26
IL281166A (en) 2021-04-29
KR102886521B1 (ko) 2025-11-17
WO2020101790A3 (en) 2020-07-09
UA129837C2 (uk) 2025-08-20
US20200069672A1 (en) 2020-03-05
IL281166B1 (en) 2025-04-01
AU2025204043A1 (en) 2025-06-19
JP2024056875A (ja) 2024-04-23
WO2020101790A2 (en) 2020-05-22
GB2591937B (en) 2023-06-07
EP3846812A2 (en) 2021-07-14
US20240016790A1 (en) 2024-01-18
JP7439096B2 (ja) 2024-02-27
MX2021002590A (es) 2021-05-31
GB202104738D0 (en) 2021-05-19
AU2019381269B2 (en) 2025-03-06
IL281166B2 (en) 2025-08-01
KR20210061357A (ko) 2021-05-27
BR112021004030A2 (pt) 2021-06-22
AU2019381269A1 (en) 2021-03-18
MA53565A (fr) 2021-07-14
CN112955145A (zh) 2021-06-11
GB2591937A (en) 2021-08-11
CL2021000531A1 (es) 2021-10-08
JP2021536506A (ja) 2021-12-27

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