CA3109723A1 - Enzymatic compositions for carbohydrate antigen cleavage, methods, uses, apparatuses and systems associated therewith - Google Patents
Enzymatic compositions for carbohydrate antigen cleavage, methods, uses, apparatuses and systems associated therewith Download PDFInfo
- Publication number
- CA3109723A1 CA3109723A1 CA3109723A CA3109723A CA3109723A1 CA 3109723 A1 CA3109723 A1 CA 3109723A1 CA 3109723 A CA3109723 A CA 3109723A CA 3109723 A CA3109723 A CA 3109723A CA 3109723 A1 CA3109723 A1 CA 3109723A1
- Authority
- CA
- Canada
- Prior art keywords
- seq
- protein
- tag
- galactosaminidase
- galnacdeacetylase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/54—Mixtures of enzymes or proenzymes covered by more than a single one of groups A61K38/44 - A61K38/46 or A61K38/51 - A61K38/53
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01049—Alpha-N-acetylgalactosaminidase (3.2.1.49)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
- C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
- C12Y305/01025—N-Acetylglucosamine-6-phosphate deacetylase (3.5.1.25)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Gastroenterology & Hepatology (AREA)
- Veterinary Medicine (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Biophysics (AREA)
- Physiology (AREA)
- Materials For Medical Uses (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862719272P | 2018-08-17 | 2018-08-17 | |
| US62/719,272 | 2018-08-17 | ||
| PCT/CA2019/051120 WO2020034042A1 (en) | 2018-08-17 | 2019-08-16 | Enzymatic compositions for carbohydrate antigen cleavage, methods, uses, apparatuses and systems associated therewith |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3109723A1 true CA3109723A1 (en) | 2020-02-20 |
Family
ID=69524510
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3109723A Pending CA3109723A1 (en) | 2018-08-17 | 2019-08-16 | Enzymatic compositions for carbohydrate antigen cleavage, methods, uses, apparatuses and systems associated therewith |
| CA3116785A Pending CA3116785A1 (en) | 2018-08-17 | 2019-08-16 | Enzymatic compositions for carbohydrate antigen cleavage on donor organs, methods and uses associated therewith |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3116785A Pending CA3116785A1 (en) | 2018-08-17 | 2019-08-16 | Enzymatic compositions for carbohydrate antigen cleavage on donor organs, methods and uses associated therewith |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US20210324361A1 (enExample) |
| EP (2) | EP3837370A4 (enExample) |
| JP (4) | JP7684216B2 (enExample) |
| CN (4) | CN112839512B (enExample) |
| AU (1) | AU2019322933B2 (enExample) |
| BR (1) | BR112021002899A2 (enExample) |
| CA (2) | CA3109723A1 (enExample) |
| WO (2) | WO2020034043A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116024183B (zh) * | 2023-02-15 | 2023-10-31 | 中国农业科学院兰州兽医研究所 | 一种用于荧光染色的重组蓝舌病毒及其构建方法 |
| WO2025213250A1 (en) * | 2024-04-11 | 2025-10-16 | The University Of British Columbia | Enzymatic compositions for b antigen cleavage, methods, uses, apparatuses and systems associated therewith |
| JP2026057100A (ja) | 2024-09-20 | 2026-04-02 | トヨタ自動車株式会社 | 電気ユニット |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4609627A (en) * | 1983-08-01 | 1986-09-02 | New York Blood Center, Inc. | Enzymatic conversion of certain sub-type A and AB erythrocytes |
| CA2272925A1 (en) * | 1996-11-21 | 1998-05-28 | Jack Goldstein | Method for conversion of blood type |
| US7767415B2 (en) * | 2001-09-25 | 2010-08-03 | Velico Medical, Inc. | Compositions and methods for modifying blood cell carbohydrates |
| WO2007053565A2 (en) | 2005-10-31 | 2007-05-10 | Zymequest, Inc. | Novel a-galactosidases |
| WO2007100294A1 (en) * | 2006-02-28 | 2007-09-07 | Kurt Nilsson | Material system for blood products |
| CA2697999C (en) * | 2009-04-24 | 2013-04-30 | Werner Hoelke | A stabilized aqueous alpha-galactosidase composition and methods relating thereto |
| JP6336392B2 (ja) | 2012-09-08 | 2018-06-06 | 株式会社オーガンテクノロジーズ | 移植のための臓器又は組織の長期維持方法 |
| CA2920293A1 (en) | 2013-08-16 | 2015-02-19 | Alexion Pharmaceuticals, Inc. | Treatment of graft rejection by administering a complement inhibitor to an organ prior to transplant |
| CN107298699B (zh) * | 2017-07-21 | 2020-09-11 | 天津大学 | 通过添加大分子拥挤试剂高效体外生物生产蛋白质的配方及方法 |
| EP3962295A1 (en) * | 2019-05-01 | 2022-03-09 | The Procter & Gamble Company | Probiotic bacterial strains that produce short chain fatty acids and compositions comprising same |
-
2019
- 2019-08-16 JP JP2021532503A patent/JP7684216B2/ja active Active
- 2019-08-16 JP JP2021507883A patent/JP7570316B2/ja active Active
- 2019-08-16 CN CN201980067904.7A patent/CN112839512B/zh active Active
- 2019-08-16 EP EP19850322.9A patent/EP3837370A4/en active Pending
- 2019-08-16 CA CA3109723A patent/CA3109723A1/en active Pending
- 2019-08-16 WO PCT/CA2019/051121 patent/WO2020034043A1/en not_active Ceased
- 2019-08-16 CA CA3116785A patent/CA3116785A1/en active Pending
- 2019-08-16 US US17/269,235 patent/US20210324361A1/en not_active Abandoned
- 2019-08-16 CN CN202310572735.0A patent/CN117044707A/zh active Pending
- 2019-08-16 BR BR112021002899-4A patent/BR112021002899A2/pt unknown
- 2019-08-16 AU AU2019322933A patent/AU2019322933B2/en active Active
- 2019-08-16 US US17/269,238 patent/US20210345601A1/en not_active Abandoned
- 2019-08-16 CN CN202411828074.4A patent/CN119662602A/zh active Pending
- 2019-08-16 EP EP19849296.9A patent/EP3852526A4/en active Pending
- 2019-08-16 CN CN201980067913.6A patent/CN112840027B/zh active Active
- 2019-08-16 WO PCT/CA2019/051120 patent/WO2020034042A1/en not_active Ceased
-
2024
- 2024-02-14 US US18/441,770 patent/US20240294895A1/en active Pending
- 2024-04-05 US US18/628,538 patent/US20250011749A1/en active Pending
- 2024-07-11 JP JP2024111653A patent/JP2024163994A/ja active Pending
-
2025
- 2025-05-15 JP JP2025081746A patent/JP2025131609A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3837370A4 (en) | 2022-09-14 |
| US20240294895A1 (en) | 2024-09-05 |
| CN112839512A (zh) | 2021-05-25 |
| JP7684216B2 (ja) | 2025-05-27 |
| CN119662602A (zh) | 2025-03-21 |
| WO2020034042A1 (en) | 2020-02-20 |
| CN112840027B (zh) | 2025-01-10 |
| CN112839512B (zh) | 2023-06-13 |
| AU2019322933A1 (en) | 2021-03-18 |
| JP2025131609A (ja) | 2025-09-09 |
| US20210345601A1 (en) | 2021-11-11 |
| EP3852526A1 (en) | 2021-07-28 |
| AU2019322933B2 (en) | 2025-08-14 |
| EP3852526A4 (en) | 2022-11-02 |
| BR112021002899A2 (pt) | 2021-05-11 |
| CN117044707A (zh) | 2023-11-14 |
| JP2024163994A (ja) | 2024-11-26 |
| CA3116785A1 (en) | 2020-02-20 |
| CN112840027A (zh) | 2021-05-25 |
| US20210324361A1 (en) | 2021-10-21 |
| US20250011749A1 (en) | 2025-01-09 |
| EP3837370A1 (en) | 2021-06-23 |
| JP2021532838A (ja) | 2021-12-02 |
| JP2021533783A (ja) | 2021-12-09 |
| WO2020034043A1 (en) | 2020-02-20 |
| JP7570316B2 (ja) | 2024-10-21 |
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