CA3089238A1 - Use of tradipitant in motion sickness - Google Patents

Use of tradipitant in motion sickness Download PDF

Info

Publication number
CA3089238A1
CA3089238A1 CA3089238A CA3089238A CA3089238A1 CA 3089238 A1 CA3089238 A1 CA 3089238A1 CA 3089238 A CA3089238 A CA 3089238A CA 3089238 A CA3089238 A CA 3089238A CA 3089238 A1 CA3089238 A1 CA 3089238A1
Authority
CA
Canada
Prior art keywords
tradipitant
motion sickness
effective amount
symptom
dose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3089238A
Other languages
English (en)
French (fr)
Inventor
Mihael H. Polymeropoulos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vanda Pharmaceuticals Inc
Original Assignee
Vanda Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vanda Pharmaceuticals Inc filed Critical Vanda Pharmaceuticals Inc
Publication of CA3089238A1 publication Critical patent/CA3089238A1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41921,2,3-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
CA3089238A 2018-09-28 2019-09-26 Use of tradipitant in motion sickness Pending CA3089238A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862737992P 2018-09-28 2018-09-28
US62/737,992 2018-09-28
US201962874927P 2019-07-16 2019-07-16
US62/874,927 2019-07-16
PCT/US2019/053107 WO2020069092A1 (en) 2018-09-28 2019-09-26 Use of tradipitant in motion sickness

Publications (1)

Publication Number Publication Date
CA3089238A1 true CA3089238A1 (en) 2020-04-02

Family

ID=68165866

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3089238A Pending CA3089238A1 (en) 2018-09-28 2019-09-26 Use of tradipitant in motion sickness

Country Status (20)

Country Link
US (2) US20220249444A1 (https=)
EP (2) EP3856338B1 (https=)
JP (1) JP7468964B2 (https=)
KR (2) KR102863233B1 (https=)
CN (1) CN111918701B (https=)
AU (1) AU2019348001B2 (https=)
BR (1) BR112020015484A2 (https=)
CA (1) CA3089238A1 (https=)
CL (1) CL2020002165A1 (https=)
DK (1) DK3856338T3 (https=)
ES (1) ES3010832T3 (https=)
FI (1) FI3856338T3 (https=)
HR (1) HRP20250097T1 (https=)
HU (1) HUE070000T2 (https=)
IL (1) IL281569B2 (https=)
MX (1) MX2020008456A (https=)
PT (1) PT3856338T (https=)
SI (1) SI3856338T1 (https=)
WO (1) WO2020069092A1 (https=)
ZA (1) ZA202004594B (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2824552T3 (es) * 2015-03-04 2021-05-12 Vanda Pharmaceuticals Inc Método de tratamiento con tradipitant
JP7791832B2 (ja) 2020-03-26 2025-12-24 バンダ・ファーマシューティカルズ・インコーポレイテッド トラジピタントによる下気道感染症の治療
WO2023019084A1 (en) * 2021-08-12 2023-02-16 Vanda Pharmaceuticals Inc. Treatment of gastric accommodation with tradipitant
US20240350469A1 (en) 2021-08-31 2024-10-24 Vanda Pharmaceuticals Inc. Treatment of lower respiratory tract infection with tradipitant
AU2023413130A1 (en) 2022-12-21 2025-06-05 Vanda Pharmaceuticals Inc. Methods of treatment with tradipitant

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1035115E (pt) * 1999-02-24 2005-01-31 Hoffmann La Roche Derivados de 4-fenilpiridina e a sua utilizacao como antagonistas do receptor nk-1
AU2003230829B8 (en) * 2002-04-26 2008-12-11 Eli Lilly And Company Triazole derivatives as tachykinin receptor antagonists
BRPI0415010B8 (pt) * 2003-10-24 2021-05-25 Lilly Co Eli formas cristalinas iv e v de {2-[1-(3,5-bis-trifluorometilbenzil)-5-piridin-4-il-1h-[1,2,3]triazol-4-il]-piridin-3-il)-(2-clorofenil)-metanona, (2-clorofenil)-[2-(2-hidróxi-2-piridin-4-il-vinil)piridin-3-il]metanona, seus processos de preparação, e composição farmacêutica sólida
EP2722045B1 (en) * 2009-11-18 2016-07-06 Helsinn Healthcare SA Compositions for treating centrally mediated nausea and vomiting
ES2824552T3 (es) * 2015-03-04 2021-05-12 Vanda Pharmaceuticals Inc Método de tratamiento con tradipitant
CN119074729A (zh) * 2017-11-17 2024-12-06 万达制药公司 使用川地匹坦治疗胃肠疾病的方法

Also Published As

Publication number Publication date
JP2022511194A (ja) 2022-01-31
JP7468964B2 (ja) 2024-04-16
EP3856338B1 (en) 2024-11-06
CL2020002165A1 (es) 2021-01-04
HRP20250097T1 (hr) 2025-03-28
CN111918701B (zh) 2024-08-02
BR112020015484A2 (pt) 2021-04-27
EP3856338A1 (en) 2021-08-04
NZ766397A (en) 2023-09-29
KR20250140634A (ko) 2025-09-25
ES3010832T3 (en) 2025-04-04
EP4450126A3 (en) 2025-02-19
SI3856338T1 (sl) 2025-04-30
US20240285588A1 (en) 2024-08-29
US20220249444A1 (en) 2022-08-11
IL281569A (en) 2021-05-31
HUE070000T2 (hu) 2025-04-28
AU2019348001A1 (en) 2020-08-06
AU2019348001B2 (en) 2023-09-21
EP4450126A2 (en) 2024-10-23
PT3856338T (pt) 2025-01-31
FI3856338T3 (fi) 2025-02-03
IL281569B2 (en) 2025-04-01
IL281569B1 (en) 2024-12-01
ZA202004594B (en) 2024-12-18
WO2020069092A1 (en) 2020-04-02
DK3856338T3 (da) 2025-02-10
CN111918701A (zh) 2020-11-10
MX2020008456A (es) 2020-09-25
KR20210067980A (ko) 2021-06-08
KR102863233B1 (ko) 2025-09-22

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