CA3085951C - Methods of treatment of hypertriglyceridemia - Google Patents

Methods of treatment of hypertriglyceridemia Download PDF

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Publication number
CA3085951C
CA3085951C CA3085951A CA3085951A CA3085951C CA 3085951 C CA3085951 C CA 3085951C CA 3085951 A CA3085951 A CA 3085951A CA 3085951 A CA3085951 A CA 3085951A CA 3085951 C CA3085951 C CA 3085951C
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CA
Canada
Prior art keywords
week
hdl
pemafibrate
subject
concentration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3085951A
Other languages
English (en)
French (fr)
Other versions
CA3085951A1 (en
Inventor
Gary Gordon
Ryu Oshima
Kazuhito SUEHIRA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kowa Co Ltd
Original Assignee
Kowa Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Co Ltd filed Critical Kowa Co Ltd
Publication of CA3085951A1 publication Critical patent/CA3085951A1/en
Application granted granted Critical
Publication of CA3085951C publication Critical patent/CA3085951C/en
Active legal-status Critical Current
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41681,3-Diazoles having a nitrogen attached in position 2, e.g. clonidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/423Oxazoles condensed with carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA3085951A 2017-12-21 2018-12-20 Methods of treatment of hypertriglyceridemia Active CA3085951C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762609048P 2017-12-21 2017-12-21
US62/609,048 2017-12-21
PCT/US2018/066976 WO2019126597A1 (en) 2017-12-21 2018-12-20 Methods of treatment of hypertrigl yceridemia

Publications (2)

Publication Number Publication Date
CA3085951A1 CA3085951A1 (en) 2019-06-27
CA3085951C true CA3085951C (en) 2022-10-11

Family

ID=66995099

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3085951A Active CA3085951C (en) 2017-12-21 2018-12-20 Methods of treatment of hypertriglyceridemia

Country Status (9)

Country Link
US (1) US20190224169A1 (enExample)
EP (1) EP3727376A4 (enExample)
JP (2) JP2021506907A (enExample)
CN (1) CN111741753A (enExample)
AU (1) AU2018393119B2 (enExample)
CA (1) CA3085951C (enExample)
MY (1) MY205171A (enExample)
SG (1) SG11202005850VA (enExample)
WO (1) WO2019126597A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024014524A1 (ja) * 2022-07-15 2024-01-18 興和株式会社 血中ldlコレステロール低下剤
WO2024167964A1 (en) * 2023-02-08 2024-08-15 Kowa Company, Ltd. Methods of treating and preventing peripheral artery disease
WO2025069226A1 (ja) * 2023-09-26 2025-04-03 興和株式会社 ペマフィブラートを含有する医薬

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2535749C (en) * 2003-09-03 2011-11-01 Kowa Co., Ltd. Ppar activating compound and pharmaceutical composition containing same
TWI407955B (zh) * 2007-03-29 2013-09-11 Kowa Co 高脂血症之預防及/或治療劑
EP2902025B1 (en) * 2012-09-27 2019-08-07 Kowa Company Ltd. Therapeutic agent for dyslipidemia
CN106470675A (zh) * 2014-06-26 2017-03-01 西玛贝医药公司 严重高甘油三酯血症的治疗
TWI691331B (zh) * 2014-09-26 2020-04-21 日商興和股份有限公司 脂質異常症治療劑
RS61403B1 (sr) * 2016-07-29 2021-02-26 Kowa Co Postupci prevencije kardiovaskularnih događaja u populacijama sa dislipidemijom sa rezidualnim rizikom

Also Published As

Publication number Publication date
JP2023181451A (ja) 2023-12-21
CA3085951A1 (en) 2019-06-27
EP3727376A1 (en) 2020-10-28
AU2018393119B2 (en) 2022-08-25
MY205171A (en) 2024-10-04
WO2019126597A1 (en) 2019-06-27
JP2021506907A (ja) 2021-02-22
EP3727376A4 (en) 2021-07-21
US20190224169A1 (en) 2019-07-25
SG11202005850VA (en) 2020-07-29
CN111741753A (zh) 2020-10-02
AU2018393119A1 (en) 2020-07-23

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Effective date: 20200615

EEER Examination request

Effective date: 20200615