CA3085662A1 - Pharmaceutical carriers containing mirnas for use in the treatment of renal cancer - Google Patents
Pharmaceutical carriers containing mirnas for use in the treatment of renal cancer Download PDFInfo
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- CA3085662A1 CA3085662A1 CA3085662A CA3085662A CA3085662A1 CA 3085662 A1 CA3085662 A1 CA 3085662A1 CA 3085662 A CA3085662 A CA 3085662A CA 3085662 A CA3085662 A CA 3085662A CA 3085662 A1 CA3085662 A1 CA 3085662A1
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- mir
- extracellular vesicle
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
- C12N2310/141—MicroRNAs, miRNAs
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
- C12N2320/32—Special delivery means, e.g. tissue-specific
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
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EP17207414 | 2017-12-14 | ||
EP17207414.8 | 2017-12-14 | ||
PCT/EP2018/084907 WO2019115748A1 (en) | 2017-12-14 | 2018-12-14 | PHARMACEUTICAL CARRIERS CONTAINING miRNAs FOR USE IN THE TREATMENT OF RENAL CANCER |
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CA3085662A1 true CA3085662A1 (en) | 2019-06-20 |
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CA3085662A Pending CA3085662A1 (en) | 2017-12-14 | 2018-12-14 | Pharmaceutical carriers containing mirnas for use in the treatment of renal cancer |
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US (1) | US11395832B2 (ja) |
EP (1) | EP3724334A1 (ja) |
JP (1) | JP7372917B2 (ja) |
CN (1) | CN111601890B (ja) |
CA (1) | CA3085662A1 (ja) |
WO (1) | WO2019115748A1 (ja) |
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KR102251864B1 (ko) | 2019-10-18 | 2021-05-14 | 지니너스 주식회사 | miR-320c를 유효성분으로 포함하는 백금계 항암제에 대한 삼중음성유방암 환자의 약물 반응성 예측용 바이오마커 조성물 |
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EP2290070B1 (en) * | 2004-05-28 | 2015-03-25 | Asuragen, Inc. | Methods and compositions involving microRNA |
WO2006126219A1 (en) | 2005-05-26 | 2006-11-30 | Fresenius Medical Care Deutschland G.M.B.H. | Liver progenitor cells |
US9085778B2 (en) | 2006-05-03 | 2015-07-21 | VL27, Inc. | Exosome transfer of nucleic acids to cells |
ES2562607T3 (es) * | 2006-07-13 | 2016-03-07 | The Ohio State University Research Foundation | MIR-21 para el diagnóstico de adenocarcinoma de colon con mal pronóstico de supervivencia |
WO2009036236A1 (en) | 2007-09-14 | 2009-03-19 | The Ohio State University Research Foundation | Mirna expression in human peripheral blood microvesicles and uses thereof |
US20090192114A1 (en) | 2007-12-21 | 2009-07-30 | Dmitriy Ovcharenko | miR-10 Regulated Genes and Pathways as Targets for Therapeutic Intervention |
CN101590243A (zh) * | 2009-06-23 | 2009-12-02 | 暨南大学 | 微小rna在制备治疗和/或预防淋巴瘤药物中的应用 |
EP2333047A1 (en) | 2009-12-09 | 2011-06-15 | Fresenius Medical Care Deutschland GmbH | Adult stem cell derived conditioned medium and/or adult stem cells for use in the therapeutic treatment of a tumor disease |
EP2363136A1 (en) | 2010-03-02 | 2011-09-07 | Fresenius Medical Care Deutschland GmbH | Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease |
DK3190177T3 (da) * | 2010-05-12 | 2022-01-31 | Prokidney | Bioaktive nyreceller |
US10716813B2 (en) | 2016-05-06 | 2020-07-21 | Unicyte Ev Ag | Pharmaceutical carriers containing miRNAs for use in the treatment of fibrotic diseases caused by hyperglycemia |
EP3658165A4 (en) * | 2017-07-26 | 2021-09-01 | Oncorus, Inc. | ONCOLYTIC VIRUS VECTORS AND USES THEREOF |
CN111527199A (zh) * | 2017-11-16 | 2020-08-11 | 得克萨斯大学体系董事会 | 用于制备来源于msc的外泌体的方法 |
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- 2018-12-14 EP EP18825630.9A patent/EP3724334A1/en active Pending
- 2018-12-14 JP JP2020532750A patent/JP7372917B2/ja active Active
- 2018-12-14 WO PCT/EP2018/084907 patent/WO2019115748A1/en unknown
- 2018-12-14 CA CA3085662A patent/CA3085662A1/en active Pending
- 2018-12-14 CN CN201880080631.5A patent/CN111601890B/zh active Active
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CN111601890A (zh) | 2020-08-28 |
WO2019115748A1 (en) | 2019-06-20 |
JP2021506804A (ja) | 2021-02-22 |
JP7372917B2 (ja) | 2023-11-01 |
CN111601890B (zh) | 2024-04-19 |
US20210069231A1 (en) | 2021-03-11 |
EP3724334A1 (en) | 2020-10-21 |
US11395832B2 (en) | 2022-07-26 |
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