CA3081979C - Nt-proanp and nt-probnp for the diagnosis of stroke - Google Patents
Nt-proanp and nt-probnp for the diagnosis of stroke Download PDFInfo
- Publication number
- CA3081979C CA3081979C CA3081979A CA3081979A CA3081979C CA 3081979 C CA3081979 C CA 3081979C CA 3081979 A CA3081979 A CA 3081979A CA 3081979 A CA3081979 A CA 3081979A CA 3081979 C CA3081979 C CA 3081979C
- Authority
- CA
- Canada
- Prior art keywords
- subject
- sample
- amount
- tia
- proanp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Brain natriuretic peptide [BNP, proBNP]; Cardionatrin; Cardiodilatin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2871—Cerebrovascular disorders, e.g. stroke, cerebral infarct, cerebral haemorrhage, transient ischemic event
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11191579 | 2011-12-01 | ||
| EP11191579.9 | 2011-12-01 | ||
| CA2856461A CA2856461C (en) | 2011-12-01 | 2012-11-29 | Nt-proanp and nt-probnp for the diagnosis of stroke |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2856461A Division CA2856461C (en) | 2011-12-01 | 2012-11-29 | Nt-proanp and nt-probnp for the diagnosis of stroke |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA3081979A1 CA3081979A1 (en) | 2013-06-06 |
| CA3081979C true CA3081979C (en) | 2023-07-11 |
Family
ID=47278813
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3081979A Active CA3081979C (en) | 2011-12-01 | 2012-11-29 | Nt-proanp and nt-probnp for the diagnosis of stroke |
| CA2856461A Active CA2856461C (en) | 2011-12-01 | 2012-11-29 | Nt-proanp and nt-probnp for the diagnosis of stroke |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2856461A Active CA2856461C (en) | 2011-12-01 | 2012-11-29 | Nt-proanp and nt-probnp for the diagnosis of stroke |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10732188B2 (https=) |
| EP (2) | EP3290924B1 (https=) |
| JP (2) | JP6059735B2 (https=) |
| CN (2) | CN107064516B (https=) |
| CA (2) | CA3081979C (https=) |
| ES (2) | ES2899923T3 (https=) |
| WO (1) | WO2013079567A2 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3206032B1 (en) * | 2014-10-10 | 2019-02-27 | Akira Matsumori | Method for detecting cardiac failure patient, method for discrimination of cardiac disease, test reagent for cardiac failure, test kit for cardiac failure, device for detecting cardiac failure, and program for detecting cardiac failure |
| KR20210038893A (ko) * | 2018-07-31 | 2021-04-08 | 에프. 호프만-라 로슈 아게 | 심방 세동의 평가에서 순환하는 dkk3(딕오프 관련 단백질 3) |
| US11931207B2 (en) | 2018-12-11 | 2024-03-19 | Eko.Ai Pte. Ltd. | Artificial intelligence (AI) recognition of echocardiogram images to enhance a mobile ultrasound device |
| US11446009B2 (en) | 2018-12-11 | 2022-09-20 | Eko.Ai Pte. Ltd. | Clinical workflow to diagnose heart disease based on cardiac biomarker measurements and AI recognition of 2D and doppler modality echocardiogram images |
| US12400762B2 (en) | 2018-12-11 | 2025-08-26 | Eko.Ai Pte. Ltd. | Automatic clinical workflow that recognizes and analyzes 2D and doppler modality echocardiogram images for automated cardiac measurements and diagnosis of cardiac amyloidosis and hypertrophic cardiomyopathy |
| US12001939B2 (en) | 2018-12-11 | 2024-06-04 | Eko.Ai Pte. Ltd. | Artificial intelligence (AI)-based guidance for an ultrasound device to improve capture of echo image views |
| US12322100B2 (en) | 2018-12-11 | 2025-06-03 | Eko.Ai Pte. Ltd. | Automatic clinical workflow that recognizes and analyzes 2D and doppler modality echocardiogram images for automated cardiac measurements and grading of aortic stenosis severity |
| US20220381794A1 (en) * | 2019-05-16 | 2022-12-01 | Fundació Hospital Universitari Vall D'hebron - Institut De Recerca | Method for selecting a patient for a reperfusion therapy |
| JP2021173559A (ja) | 2020-04-21 | 2021-11-01 | 株式会社デンソー | 物理量計測装置 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
| GB9211686D0 (en) | 1992-06-03 | 1992-07-15 | Medisinsk Innovation A S | Chemical compounds |
| US7632647B2 (en) | 2001-04-13 | 2009-12-15 | Biosite Incorporated | Use of B-type natriuretic peptide as a prognostic indicator in acute coronary syndromes |
| EP1322957B1 (en) | 2001-05-04 | 2009-08-12 | Biosite Incorporated | Diagnostic markers of acute coronary syndromes and methods of use thereof |
| DE60233949D1 (de) | 2001-08-20 | 2009-11-19 | Biosite Inc | Diagnostische marker für schlaganfall und hirntrauma sowie verfahren zur verwendung davon |
| ATE462001T1 (de) * | 2002-12-24 | 2010-04-15 | Nitto Boseki Co Ltd | Markerproteine zur diagnose einer lebererkrankung und verfahren zur diagnose einer lebererkrankung damit |
| JP2006526140A (ja) * | 2002-12-24 | 2006-11-16 | バイオサイト インコーポレイテッド | 鑑別診断のためのマーカーおよびその使用方法 |
| US20050181386A1 (en) * | 2003-09-23 | 2005-08-18 | Cornelius Diamond | Diagnostic markers of cardiovascular illness and methods of use thereof |
| EP1582597A1 (en) | 2004-03-29 | 2005-10-05 | Aventis Pharma Deutschland GmbH | Method of diagnosis of a predisposition to develop thrombotic disease and its uses |
| US20060166303A1 (en) * | 2005-01-24 | 2006-07-27 | Eberhard Spanuth | Use of cardiac hormones for assessing a cardiovascular risk with respect to the administration of anti-inflammatory drugs |
| DK1849009T3 (da) | 2005-01-24 | 2009-01-12 | Hoffann La Roche Ag F | Anvendelse af cardiachormoner til diagnose af cardiovaskulære risici som fölge af en administration af antiinflammatoriske lægemidler |
| JP4828550B2 (ja) * | 2005-02-17 | 2011-11-30 | エフ．ホフマン−ラ ロシュ アーゲー | 心機能障害を診断するためのＮＴ−ｐｒｏＡＮＰ／ＮＴ−ｐｒｏＢＮＰ比の使用 |
| EP1731910A1 (en) * | 2005-06-07 | 2006-12-13 | F. Hoffmann-La Roche Ag | Use of NT-proANP and NT-proBNP for diagnosing cardiac diseases |
| DE102005048899A1 (de) * | 2005-10-12 | 2007-04-19 | Sanofi-Aventis Deutschland Gmbh | Verfahren zur Diagnose thromboembolischer Erkrankungen und koronarer Herzerkrankungen |
| ES2344993T3 (es) * | 2006-03-24 | 2010-09-13 | F. Hoffmann-La Roche Ag | Medios y metodos para la diferenciacion de la necrosis de miocardio aguda y cronica en pacientes sintomaticos. |
| EP1882945A1 (en) | 2006-07-28 | 2008-01-30 | F.Hoffmann-La Roche Ag | Means and methods for the differentiation of cardiac and pulmonary causes of acute shortness of breath |
| ATE449966T1 (de) * | 2006-09-15 | 2009-12-15 | Hoffmann La Roche | Biochemische marker für akute lungenembolie |
| JP2011501113A (ja) | 2007-10-10 | 2011-01-06 | エフ．ホフマン−ラ ロシュ アーゲー | 急性冠症候群を有する患者での既存の心筋機能不全の評価のためのナトリウム利尿ペプチド／トロポニン比 |
| CN102257386B (zh) * | 2008-10-24 | 2014-12-31 | B.R.A.H.M.S有限公司 | 通过测定标志肽的水平在已患过中风或短暂性缺血性发作的患者中进行预后和风险评估 |
| CA2751090A1 (en) * | 2009-01-30 | 2010-08-05 | Electrophoretics Limited | Method for the in vitro diagnosis of stroke |
| EP2466311A1 (en) | 2010-12-17 | 2012-06-20 | Roche Diagnostics GmbH | sFlt1 in patients with ischemic stroke |
-
2012
- 2012-11-29 EP EP17196637.7A patent/EP3290924B1/en active Active
- 2012-11-29 CN CN201610812599.8A patent/CN107064516B/zh active Active
- 2012-11-29 JP JP2014543882A patent/JP6059735B2/ja active Active
- 2012-11-29 CA CA3081979A patent/CA3081979C/en active Active
- 2012-11-29 ES ES17196637T patent/ES2899923T3/es active Active
- 2012-11-29 CN CN201280068882.4A patent/CN104094121B/zh active Active
- 2012-11-29 ES ES12794941.0T patent/ES2656082T3/es active Active
- 2012-11-29 WO PCT/EP2012/073897 patent/WO2013079567A2/en not_active Ceased
- 2012-11-29 CA CA2856461A patent/CA2856461C/en active Active
- 2012-11-29 EP EP12794941.0A patent/EP2786154B1/en active Active
-
2014
- 2014-05-30 US US14/291,676 patent/US10732188B2/en active Active
-
2016
- 2016-12-09 JP JP2016239317A patent/JP6441885B2/ja active Active
-
2020
- 2020-06-30 US US16/916,809 patent/US20200333360A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US10732188B2 (en) | 2020-08-04 |
| CN104094121A (zh) | 2014-10-08 |
| EP2786154B1 (en) | 2017-11-01 |
| CA2856461C (en) | 2020-08-18 |
| WO2013079567A2 (en) | 2013-06-06 |
| CN104094121B (zh) | 2016-10-26 |
| HK1201327A1 (en) | 2015-08-28 |
| JP2017075959A (ja) | 2017-04-20 |
| CA2856461A1 (en) | 2013-06-06 |
| EP3290924B1 (en) | 2021-10-13 |
| CN107064516A (zh) | 2017-08-18 |
| WO2013079567A3 (en) | 2013-08-29 |
| ES2656082T3 (es) | 2018-02-23 |
| EP3290924A1 (en) | 2018-03-07 |
| US20200333360A1 (en) | 2020-10-22 |
| JP2015504519A (ja) | 2015-02-12 |
| US20140274793A1 (en) | 2014-09-18 |
| EP2786154A2 (en) | 2014-10-08 |
| ES2899923T3 (es) | 2022-03-15 |
| CN107064516B (zh) | 2019-08-02 |
| JP6441885B2 (ja) | 2018-12-19 |
| JP6059735B2 (ja) | 2017-01-11 |
| CA3081979A1 (en) | 2013-06-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20200605 |
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| MPN | Maintenance fee for patent paid |
Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 12TH ANNIV.) - STANDARD Year of fee payment: 12 |
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| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20241114 |
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| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20250530 |
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| MPN | Maintenance fee for patent paid |
Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 13TH ANNIV.) - STANDARD Year of fee payment: 13 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20251023 |
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| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20251023 |