CA3076750A1 - Stable cannabinoid compositions - Google Patents

Stable cannabinoid compositions Download PDF

Info

Publication number
CA3076750A1
CA3076750A1 CA3076750A CA3076750A CA3076750A1 CA 3076750 A1 CA3076750 A1 CA 3076750A1 CA 3076750 A CA3076750 A CA 3076750A CA 3076750 A CA3076750 A CA 3076750A CA 3076750 A1 CA3076750 A1 CA 3076750A1
Authority
CA
Canada
Prior art keywords
aqueous
corresponds
alkoxylated solvent
temperature
alkoxylated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3076750A
Other languages
English (en)
French (fr)
Inventor
Ilse Knoller
Thomas SOWIK
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sino German M&a Service GmbH
Original Assignee
Sino German M&a Service GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sino German M&a Service GmbH filed Critical Sino German M&a Service GmbH
Publication of CA3076750A1 publication Critical patent/CA3076750A1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/01Hydrocarbons
    • A61K31/015Hydrocarbons carbocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355Tocopherols, e.g. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/658Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA3076750A 2017-07-07 2018-07-06 Stable cannabinoid compositions Pending CA3076750A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17180380.2 2017-07-07
EP17180380.2A EP3424493A1 (en) 2017-07-07 2017-07-07 Stable cannabinoid compositions
PCT/EP2018/068452 WO2019008179A1 (en) 2017-07-07 2018-07-06 STABLE CANNABINOID COMPOSITIONS

Publications (1)

Publication Number Publication Date
CA3076750A1 true CA3076750A1 (en) 2019-01-10

Family

ID=59315425

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3076750A Pending CA3076750A1 (en) 2017-07-07 2018-07-06 Stable cannabinoid compositions

Country Status (10)

Country Link
US (1) US11752126B2 (enExample)
EP (2) EP3424493A1 (enExample)
JP (1) JP7186222B2 (enExample)
KR (1) KR102680507B1 (enExample)
CN (2) CN115120558A (enExample)
AU (1) AU2018296679B2 (enExample)
CA (1) CA3076750A1 (enExample)
EA (1) EA202090177A1 (enExample)
IL (1) IL271892B2 (enExample)
WO (1) WO2019008179A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230000770A1 (en) * 2019-12-06 2023-01-05 Hanyi Biotechnology (Beijing) Co., Ltd Cannabinoid nanomicelle preparation and method for preparing same

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202022000150U1 (de) 2022-01-20 2022-07-07 Solmic Bio Tech Gmbh Maske für medizinische oder kosmetische Zwecke mit mizellierten Extrakten
EP4275694A1 (de) 2022-05-13 2023-11-15 Solmic Biotech GmbH Verwendung von solubilisaten in erzeugnissen zur topischen anwendung
CN119278046A (zh) 2022-01-20 2025-01-07 索米尔生物技术有限公司 具有微胶粒提取物的用于医学或化妆品目的的面膜
CN117986017B (zh) * 2023-11-27 2025-11-21 陕西师范大学 一种(Sm2-aYa)Ba4CuBiO10纳米粉体及用其改善单畴SmBCO超导块材性能的方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5952004A (en) 1994-03-18 1999-09-14 Shire Laboratories Inc. Emulsified drug delivery systems
AU5273200A (en) * 1999-05-24 2000-12-12 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
US20030236236A1 (en) 1999-06-30 2003-12-25 Feng-Jing Chen Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs
DE60313299T2 (de) * 2002-03-01 2008-01-03 Yissum Research Development Company Of The Hebrew University Of Jerusalem Selbstemulgierende systeme zur abgabe von taxoiden
US20080045559A1 (en) * 2003-10-29 2008-02-21 Sonus Pharmaceuticals, Inc. Tocopherol-modified therapeutic drug compounds
WO2007016175A1 (en) 2005-07-28 2007-02-08 Guasch Michael N Fuel repellent compositions, fabrics and articles
US7402325B2 (en) * 2005-07-28 2008-07-22 Phoenix Biotechnology, Inc. Supercritical carbon dioxide extract of pharmacologically active components from Nerium oleander
TWI392507B (zh) * 2006-10-20 2013-04-11 Solvay Pharm Bv 包埋的膠束奈米顆粒
EP2083799A1 (en) 2006-10-20 2009-08-05 Solvay Pharmaceuticals B.V. Micellar nanoparticles of chemical substances
HUE032158T2 (en) * 2008-10-31 2017-09-28 Univ Mississippi Process for the preparation of delta9-THC amino acid esters
WO2012050978A1 (en) * 2010-09-29 2012-04-19 MyCell Holdings Limited Formulations of ubiquinol and resveratrol esters
US8808734B2 (en) 2011-07-11 2014-08-19 Full Spectrum Laboratories Limited Cannabinoid formulations
US20140314672A1 (en) * 2013-04-06 2014-10-23 Igdrasol, Inc. Nanoparticle therapeutic agents, their formulations, and methods of their use
US9861611B2 (en) * 2014-09-18 2018-01-09 Virun, Inc. Formulations of water-soluble derivatives of vitamin E and soft gel compositions, concentrates and powders containing same
WO2017072774A1 (en) * 2015-10-29 2017-05-04 Solubest Ltd Pharmaceutical compositions for transmucosal delivery

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230000770A1 (en) * 2019-12-06 2023-01-05 Hanyi Biotechnology (Beijing) Co., Ltd Cannabinoid nanomicelle preparation and method for preparing same

Also Published As

Publication number Publication date
KR102680507B1 (ko) 2024-07-01
EA202090177A1 (ru) 2020-06-05
CN115120558A (zh) 2022-09-30
CN111246844A (zh) 2020-06-05
IL271892A (en) 2020-02-27
JP7186222B2 (ja) 2022-12-08
EP3424493A1 (en) 2019-01-09
US11752126B2 (en) 2023-09-12
WO2019008179A1 (en) 2019-01-10
IL271892B2 (en) 2023-08-01
KR20200037247A (ko) 2020-04-08
US20200237713A1 (en) 2020-07-30
AU2018296679A1 (en) 2020-02-20
JP2020527170A (ja) 2020-09-03
IL271892B1 (en) 2023-04-01
EP3675825A1 (en) 2020-07-08
AU2018296679B2 (en) 2024-07-25

Similar Documents

Publication Publication Date Title
AU2018296678B2 (en) Stable cannabinoid compositions
AU2018296679B2 (en) Stable cannabinoid compositions
JP4463551B2 (ja) 改良された生物学的利用能を有する製剤における高分子量で親油性で経口摂取可能な生物活性物質
JP3103430B2 (ja) 脂溶性抗酸化剤混合物
MXPA02008295A (es) Soluciones de acido ascorbico estabilizado; su uso; proceso para su obtencion; y formaciones que las contienen.
BRPI0708773A2 (pt) mÉtodo para solubilizaÇço, dispersço e estabilizaÇço de substÂncias, produtos manufaturados de acordo com o mÉtodo, bem como uso dos mesmos
US20050238675A1 (en) Water-soluble formulations of fat soluble vitamins and pharmaceutical agents and their applications
US20220370379A1 (en) Cannabinoid-containing additive and method therefor
KR20140071913A (ko) 식품 조성물 및 이를 포함하는 연질 캡슐
Papas Vitamin E TPGS and its applications in nutraceuticals
US20230058895A1 (en) Physiologically acceptable eutectic mixtures of cannabidiol
EA044031B1 (ru) Стабильная композиция каннабиноида
RU2303036C2 (ru) Солюбилизат из аскорбиновой кислоты и эмульгатора, смесь солюбилизатов, способ изготовления солюбилизата и его применение (варианты)
KR20240137658A (ko) 방부 효과를 부여한 나노에멀션
US20210353588A1 (en) Dietary supplement composition comprising of cannabis sativa extracts
JP7752233B2 (ja) 親油性化合物の改善された経口バイオアベイラビリティを有する自己乳化薬物送達配合物
RS51028B (sr) Postupak za solubilizaciju, disperziju i stabilizaciju supstanci, proizvodi proizvedeni po ovom postupku kao i upotreba istih

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20230704

EEER Examination request

Effective date: 20230704