CA3076547A1 - Novel anti-hla-a2 antibodies and uses thereof - Google Patents
Novel anti-hla-a2 antibodies and uses thereof Download PDFInfo
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- CA3076547A1 CA3076547A1 CA3076547A CA3076547A CA3076547A1 CA 3076547 A1 CA3076547 A1 CA 3076547A1 CA 3076547 A CA3076547 A CA 3076547A CA 3076547 A CA3076547 A CA 3076547A CA 3076547 A1 CA3076547 A1 CA 3076547A1
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07K—PEPTIDES
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- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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- C07K—PEPTIDES
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- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
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- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K2319/60—Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]
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| US62/691,027 | 2018-06-28 | ||
| PCT/CA2018/051174 WO2019056106A1 (en) | 2017-09-20 | 2018-09-20 | NOVEL ANTI-HLA-A2 ANTIBODIES AND USES THEREOF |
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| WO2018183293A1 (en) | 2017-03-28 | 2018-10-04 | The Trustees Of The University Of Pennsylvania | Methods to protect transplanted tissue from rejection |
| KR102742220B1 (ko) | 2017-09-19 | 2024-12-17 | 더 유니버시티 오브 브리티쉬 콜롬비아 | 항-hla-a2 항체 및 그 사용 방법 |
| CA3146013A1 (en) | 2019-07-09 | 2021-01-14 | The Children's Mercy Hospital | Engineered regulatory t cells |
| EP4013447A4 (en) * | 2019-08-16 | 2024-05-29 | H. Lee Moffitt Cancer Center & Research Institute, Inc. | ANTI-CD83 CHIMERIC ANTIGEN RECEPTOR EXPRESSING REGULATORY T CELLS |
| CN111440246B (zh) * | 2020-04-16 | 2022-03-18 | 成都仕康美生物科技有限公司 | 靶向HLA-B的嵌合抗原受体、编码基因、CAR-Tregs细胞及其制备方法、用途 |
| CN111393533B (zh) * | 2020-04-16 | 2021-05-11 | 成都仕康美生物科技有限公司 | 靶向HLA-A的嵌合抗原受体、编码基因、CAR-Tregs细胞及其制备方法、用途 |
| CA3188867A1 (en) | 2020-08-20 | 2022-02-24 | Xueyin Wang | Compositions and methods for treating ceacam positive cancers |
| US20240358833A1 (en) * | 2021-08-10 | 2024-10-31 | The Regents Of The University Of California | Hla-a2-specific regulatory t cells |
| US20250099584A1 (en) * | 2022-02-18 | 2025-03-27 | Institut National de la Santé et de la Recherche Médicale | Use of tcr-deficient car-tregs in combination with anti-tcr complex monoclonal antibodies for inducing durable tolerance |
| CN114316056A (zh) * | 2022-03-02 | 2022-04-12 | 天津一瑞生物科技股份有限公司 | 一种鼠抗ndm型碳青霉烯酶杂交瘤细胞株，单克隆抗体及应用 |
| CN118891286A (zh) * | 2022-03-08 | 2024-11-01 | 瓦克斯细胞生物 | Pd-l1特异性嵌合抗原受体及包含其的免疫细胞 |
| WO2026008994A1 (en) | 2024-07-04 | 2026-01-08 | Quell Therapeutics Limited | Expression construct |
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| ATE297465T1 (de) | 1991-11-25 | 2005-06-15 | Enzon Inc | Verfahren zur herstellung von multivalenten antigenbindenden proteinen |
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| EP2295588B1 (en) | 2004-05-27 | 2018-03-07 | The Trustees Of The University Of Pennsylvania | Novel artificial antigen presenting cells and uses thefor |
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| JP2015180607A (ja) * | 2012-08-01 | 2015-10-15 | 国立大学法人 東京大学 | 移植片対宿主病などの造血幹細胞移植に伴う疾患を治療することのできる抗体およびその機能断片並びにこれらを含んでなる医薬組成物 |
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| CN103739667B (zh) * | 2013-09-24 | 2017-08-25 | 上海宇研生物技术有限公司 | 卵巢癌特异的肿瘤抗原肽及其制备方法 |
| EP3263595A1 (en) | 2016-06-30 | 2018-01-03 | Medizinische Hochschule Hannover | Fusion protein for use in the treatment of hvg disease |
| WO2018183293A1 (en) | 2017-03-28 | 2018-10-04 | The Trustees Of The University Of Pennsylvania | Methods to protect transplanted tissue from rejection |
| KR102742220B1 (ko) | 2017-09-19 | 2024-12-17 | 더 유니버시티 오브 브리티쉬 콜롬비아 | 항-hla-a2 항체 및 그 사용 방법 |
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| SG11202002532XA (en) | 2020-04-29 |
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| CN111448216B (zh) | 2023-11-07 |
| MX2020003047A (es) | 2020-10-22 |
| IL273401A (en) | 2020-05-31 |
| EP3684822A1 (en) | 2020-07-29 |
| NZ762829A (en) | 2025-02-28 |
| KR102740924B1 (ko) | 2024-12-13 |
| JP7317023B2 (ja) | 2023-07-28 |
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