CA3075442C - Pct and pro-adm as markers for monitoring antibiotic treatment - Google Patents

Pct and pro-adm as markers for monitoring antibiotic treatment Download PDF

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Publication number
CA3075442C
CA3075442C CA3075442A CA3075442A CA3075442C CA 3075442 C CA3075442 C CA 3075442C CA 3075442 A CA3075442 A CA 3075442A CA 3075442 A CA3075442 A CA 3075442A CA 3075442 C CA3075442 C CA 3075442C
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CA
Canada
Prior art keywords
proadm
fragment
sample
level
pct
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3075442A
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English (en)
French (fr)
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CA3075442A1 (en
Inventor
Darius Wilson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BRAHMS GmbH
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BRAHMS GmbH
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=59887051&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA3075442(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by BRAHMS GmbH filed Critical BRAHMS GmbH
Publication of CA3075442A1 publication Critical patent/CA3075442A1/en
Application granted granted Critical
Publication of CA3075442C publication Critical patent/CA3075442C/en
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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/26—Infectious diseases, e.g. generalised sepsis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
CA3075442A 2017-09-13 2018-09-13 Pct and pro-adm as markers for monitoring antibiotic treatment Active CA3075442C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17190913 2017-09-13
EP17190913.8 2017-09-13
PCT/EP2018/074724 WO2019053117A1 (en) 2017-09-13 2018-09-13 PCT AND PRO-ADM USED AS CONTROL MARKERS IN ANTIBIOTIC TREATMENT

Publications (2)

Publication Number Publication Date
CA3075442A1 CA3075442A1 (en) 2019-03-21
CA3075442C true CA3075442C (en) 2024-04-02

Family

ID=59887051

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3075442A Active CA3075442C (en) 2017-09-13 2018-09-13 Pct and pro-adm as markers for monitoring antibiotic treatment

Country Status (10)

Country Link
US (1) US20200264199A1 (https=)
EP (2) EP3682241B2 (https=)
JP (2) JP7258860B2 (https=)
CN (1) CN111094981B (https=)
BR (1) BR112020004150A2 (https=)
CA (1) CA3075442C (https=)
DK (1) DK3682241T4 (https=)
ES (1) ES2913298T5 (https=)
WO (1) WO2019053117A1 (https=)
ZA (1) ZA202001108B (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111094981B (zh) 2017-09-13 2024-04-16 B.R.A.H.M.S有限公司 Pct和pro-adm作为监测抗生素治疗的标记物
RU2724186C1 (ru) * 2020-01-23 2020-06-22 Наталья Борисовна Гусева Способ лечения детей раннего возраста с рецидивирующей инфекцией мочевой системы

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2570703B1 (fr) 1984-09-26 1988-07-08 Commissariat Energie Atomique Complexes macropolycycliques de terres rares et application a titre de marqueurs fluorescents
US4882733A (en) 1987-03-13 1989-11-21 Ford Aerospace Corporation Method and apparatus for combining encoding and modulation
FR2664699B1 (fr) 1990-07-13 1995-08-18 Cis Bio Int Procede d'amplification du signal d'emission d'un compose luminescent.
CN103123359B (zh) * 2007-08-03 2015-07-29 B.R.A.H.M.S有限公司 降钙素原(pct)在患原发性非传染疾病的患者的风险分级和预后中的应用
JP5989965B2 (ja) * 2008-01-08 2016-09-07 メルク シャープ エンド ドーム リミテッド ２−｛４−［（３ｓ）−ピペリジン−３−イル］フェニル｝−２ｈ−インダゾール−７−カルボキサミドの薬学的に許容される塩
EP2438447B1 (en) 2009-06-05 2015-02-18 B.R.A.H.M.S GmbH Detection of bacterial infections in subjects suffering from dyspnea.
EP2545379B1 (en) * 2010-03-08 2015-09-30 B.R.A.H.M.S GmbH Procalcitonin for the diagnosis of bacterial infections and guidance of antibiotic treatment in patients with non-specific complaints
WO2012059477A1 (en) * 2010-11-01 2012-05-10 B.R.A.H.M.S Gmbh Prognosis and risk assessment of patients with non-specific complaints
US11067586B2 (en) * 2011-11-16 2021-07-20 Sphingotec Gmbh Adrenomedullin assays and methods for determining mature adrenomedullin
EP2637023A1 (en) * 2012-03-08 2013-09-11 B.R.A.H.M.S GmbH Prediction of outcome in patients with chronic obstructive pulmonary disease
EP2976646B1 (en) * 2013-03-20 2020-08-19 sphingotec GmbH Adrenomedullin to guide therapy of blood pressure decline
CN111094981B (zh) 2017-09-13 2024-04-16 B.R.A.H.M.S有限公司 Pct和pro-adm作为监测抗生素治疗的标记物

Also Published As

Publication number Publication date
CN111094981B (zh) 2024-04-16
ZA202001108B (en) 2022-08-31
EP3682241A1 (en) 2020-07-22
EP4027145A1 (en) 2022-07-13
RU2020111718A3 (https=) 2022-02-01
WO2019053117A1 (en) 2019-03-21
RU2020111718A (ru) 2021-10-13
EP3682241B2 (en) 2025-09-10
US20200264199A1 (en) 2020-08-20
JP7258860B2 (ja) 2023-04-17
DK3682241T4 (da) 2025-10-06
JP2020533603A (ja) 2020-11-19
DK3682241T3 (da) 2022-05-16
ES2913298T3 (es) 2022-06-01
CN111094981A (zh) 2020-05-01
CA3075442A1 (en) 2019-03-21
EP3682241B1 (en) 2022-03-30
WO2019053117A8 (en) 2021-01-21
BR112020004150A2 (pt) 2020-09-08
ES2913298T5 (en) 2026-01-02
JP2023095851A (ja) 2023-07-06

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