CA3073146C - Use of 2-[(3z)-6-fluoro-2-methyl-3-[(4-methylsulfinylphenyl)methylidene]inden-1--yl] acetic acid for making a healing preparation for wounds in patients with diabetes - Google Patents

Use of 2-[(3z)-6-fluoro-2-methyl-3-[(4-methylsulfinylphenyl)methylidene]inden-1--yl] acetic acid for making a healing preparation for wounds in patients with diabetes Download PDF

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Publication number
CA3073146C
CA3073146C CA3073146A CA3073146A CA3073146C CA 3073146 C CA3073146 C CA 3073146C CA 3073146 A CA3073146 A CA 3073146A CA 3073146 A CA3073146 A CA 3073146A CA 3073146 C CA3073146 C CA 3073146C
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CA
Canada
Prior art keywords
diabetes
acetic acid
fluoro
wounds
inden
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Application number
CA3073146A
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English (en)
French (fr)
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CA3073146A1 (en
Inventor
Mikolaj Tomulewicz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyzsza Szkola Medyczna W Bialymstoku
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Wyzsza Szkola Medyczna W Bialymstoku
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Publication of CA3073146A1 publication Critical patent/CA3073146A1/en
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA3073146A 2017-05-04 2018-04-11 Use of 2-[(3z)-6-fluoro-2-methyl-3-[(4-methylsulfinylphenyl)methylidene]inden-1--yl] acetic acid for making a healing preparation for wounds in patients with diabetes Active CA3073146C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PL421491A PL237474B1 (pl) 2017-05-04 2017-05-04 Nowe zastosowanie kwasu 2-[(3Z)-6-fluoro-2-metylo-3-[(4-metylosulfinylofenylo) metylideno]inden-1-ylo] octowego
PLP.421491 2017-05-04
PCT/PL2018/000036 WO2018203762A1 (en) 2017-05-04 2018-04-11 The new use of 2-[(3z)-6-fluoro-2-methyl-3-[(4-methylsulfinylphenyl) methylidene]inden-1 -yl] acetic acid

Publications (2)

Publication Number Publication Date
CA3073146A1 CA3073146A1 (en) 2018-11-08
CA3073146C true CA3073146C (en) 2023-10-03

Family

ID=63998341

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3073146A Active CA3073146C (en) 2017-05-04 2018-04-11 Use of 2-[(3z)-6-fluoro-2-methyl-3-[(4-methylsulfinylphenyl)methylidene]inden-1--yl] acetic acid for making a healing preparation for wounds in patients with diabetes

Country Status (6)

Country Link
US (1) US20200129459A1 (pl)
EP (1) EP3618823A4 (pl)
CN (1) CN110740726A (pl)
CA (1) CA3073146C (pl)
PL (1) PL237474B1 (pl)
WO (1) WO2018203762A1 (pl)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6187822B1 (en) * 1999-06-11 2001-02-13 University Of Medicine & Dentistry Of Nj Wound treatment through inhibition of adenosine diphosphate ribosyl transferase
AU2001259668A1 (en) * 2000-05-09 2001-11-20 The Institute For Pharmaceutical Discovery Llc Methods for testing compounds useful for treating diabetic complications
US8487128B2 (en) * 2002-11-26 2013-07-16 Chs Pharma, Inc. Protection of normal cells
EP1865972B1 (en) * 2005-03-23 2013-11-06 CHS Pharma, Inc. Treatment or prevention of cancer and precancerous disorders
WO2011088474A2 (en) 2010-01-15 2011-07-21 Zirus, Inc. Sulindac and sulindac derivatives and their uses related to infection
US20120295979A1 (en) 2011-05-03 2012-11-22 Florida Atlantic University Use of sulindac for protecting retinal pigment epithelial cells against oxidative stress
WO2014160702A1 (en) * 2013-03-25 2014-10-02 Chs Pharma, Inc. Retinopathy treatment

Also Published As

Publication number Publication date
US20200129459A1 (en) 2020-04-30
PL237474B1 (pl) 2021-04-19
PL421491A1 (pl) 2018-11-05
EP3618823A1 (en) 2020-03-11
EP3618823A4 (en) 2021-01-27
CA3073146A1 (en) 2018-11-08
WO2018203762A1 (en) 2018-11-08
CN110740726A (zh) 2020-01-31

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