CA3058023A1 - Treatment of inflammatory diseases with inhibitors of c5a activity - Google Patents
Treatment of inflammatory diseases with inhibitors of c5a activity Download PDFInfo
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- CA3058023A1 CA3058023A1 CA3058023A CA3058023A CA3058023A1 CA 3058023 A1 CA3058023 A1 CA 3058023A1 CA 3058023 A CA3058023 A CA 3058023A CA 3058023 A CA3058023 A CA 3058023A CA 3058023 A1 CA3058023 A1 CA 3058023A1
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Classifications
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- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
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- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
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- C07K—PEPTIDES
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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Landscapes
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- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17164573.2 | 2017-04-03 | ||
| EP17164573 | 2017-04-03 | ||
| EP17177657 | 2017-06-23 | ||
| EP17177657.8 | 2017-06-23 | ||
| EP17189938.8 | 2017-09-07 | ||
| EP17189938 | 2017-09-07 | ||
| PCT/EP2018/050146 WO2018184739A1 (en) | 2017-04-03 | 2018-01-03 | Treatment of inflammatory diseases with inhibitors of c5a activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3058023A1 true CA3058023A1 (en) | 2018-10-11 |
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| CA3058023A Pending CA3058023A1 (en) | 2017-04-03 | 2018-01-03 | Treatment of inflammatory diseases with inhibitors of c5a activity |
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| RU2824998C2 (ru) * | 2018-11-30 | 2024-08-19 | Кемосентрикс, Инк. | Лекарственные формы в виде капсул |
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| KR101463631B1 (ko) | 2006-03-31 | 2014-11-19 | 추가이 세이야쿠 가부시키가이샤 | 항체의 혈중 동태를 제어하는 방법 |
| RU2510400C9 (ru) | 2007-09-26 | 2014-07-20 | Чугаи Сейяку Кабусики Кайся | Способ модификации изоэлектрической точки антитела с помощью аминокислотных замен в cdr |
| US20110111406A1 (en) | 2008-04-11 | 2011-05-12 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly |
| WO2012073992A1 (ja) | 2010-11-30 | 2012-06-07 | 中外製薬株式会社 | 複数分子の抗原に繰り返し結合する抗原結合分子 |
| AR103161A1 (es) | 2014-12-19 | 2017-04-19 | Chugai Pharmaceutical Co Ltd | Anticuerpos antimiostatina y regiones fc variantes así como métodos de uso |
| AR103162A1 (es) | 2014-12-19 | 2017-04-19 | Chugai Pharmaceutical Co Ltd | Anticuerpos anti-c5 y métodos para su uso |
| EP3494991A4 (en) | 2016-08-05 | 2020-07-29 | Chugai Seiyaku Kabushiki Kaisha | COMPOSITION FOR THE PROPHYLAXIS OR TREATMENT OF IL-8 RELATED DISEASES |
| ES2893769T3 (es) | 2017-04-03 | 2022-02-10 | Inflarx Gmbh | Tratamiento de enfermedades inflamatorias con inhibidores de la actividad de C5a |
| US10376595B2 (en) | 2017-04-03 | 2019-08-13 | Inflarx Gmbh | Treatment of inflammatory diseases with inhibitors of C5a activity |
| EP3642230A1 (en) * | 2017-06-23 | 2020-04-29 | InflaRx GmbH | Treatment of inflammatory diseases with inhibitors of c5a activity |
| ES2943492T3 (es) | 2018-11-30 | 2023-06-13 | Chemocentryx Inc | Formulación de cápsulas |
| CN113543796A (zh) * | 2019-03-08 | 2021-10-22 | Ra制药公司 | 齐鲁考普作为深层组织穿透性c5抑制剂 |
| CN119874606A (zh) | 2019-03-11 | 2025-04-25 | 因弗拉克斯有限责任公司 | 作为C5a受体调节剂的稠合哌啶基双环和相关化合物 |
| EP3958842A1 (en) * | 2019-04-24 | 2022-03-02 | RA Pharmaceuticals, Inc. | Compositions and methods for modulating complement activity |
| TWI869528B (zh) | 2020-01-13 | 2025-01-11 | 美商威特拉公司 | C5ar1抗體分子及其用途 |
| KR20230045075A (ko) * | 2020-08-12 | 2023-04-04 | 이나뜨 파르마 에스.에이. | 아브도랄리맙을 사용한 피하 항-C5aR 길항제 치료 용법 |
| CN116529241A (zh) * | 2020-10-28 | 2023-08-01 | 坎莫森特里克斯公司 | 治疗化脓性汗腺炎的方法 |
| JP2023548117A (ja) * | 2020-10-28 | 2023-11-15 | ケモセントリックス， インコーポレイテッド | 化膿性汗腺炎を処置する方法 |
| AU2022207985A1 (en) | 2021-01-13 | 2023-07-06 | Visterra, Inc. | Humanized complement 5a receptor 1 antibodies and methods of use thereof |
| CN116036233A (zh) * | 2023-01-10 | 2023-05-02 | 中山大学附属第八医院（深圳福田） | 小分子化合物pmx 53在制备抑制血管钙化和血管纤维化药物中的应用 |
| US12180274B2 (en) | 2023-05-26 | 2024-12-31 | Inflarx Gmbh | Treatment of pneumonia and ARDS with inhibitors of C5a and IL-6 activity |
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| US4704355A (en) | 1985-03-27 | 1987-11-03 | New Horizons Diagnostics Corporation | Assay utilizing ATP encapsulated within liposome particles |
| CA2025907A1 (en) | 1989-09-21 | 1991-03-22 | Franklin D. Collins | Method of transporting compositions across the blood brain barrier |
| ATE139258T1 (de) | 1990-01-12 | 1996-06-15 | Cell Genesys Inc | Erzeugung xenogener antikörper |
| US6074642A (en) | 1994-05-02 | 2000-06-13 | Alexion Pharmaceuticals, Inc. | Use of antibodies specific to human complement component C5 for the treatment of glomerulonephritis |
| AUPO755097A0 (en) | 1997-06-25 | 1997-07-17 | University Of Queensland, The | Receptor agonist and antagonist |
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| GB0617734D0 (en) | 2006-09-08 | 2006-10-18 | Evolutec Ltd | Method of treating peripheral nerve disorders |
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| EP2327725A1 (en) | 2009-11-26 | 2011-06-01 | InflaRx GmbH | Anti-C5a binding moieties with high blocking activity |
| HRP20171176T1 (hr) | 2010-06-24 | 2017-10-06 | Chemocentryx, Inc. | C5ar antagonisti |
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| WO2016044419A1 (en) | 2014-09-16 | 2016-03-24 | Alnylam Pharmaceuticals, Inc. | Complement component c5 irna compositions and methods of use thereof |
| ES2719876T3 (es) | 2014-10-15 | 2019-07-16 | Alexion Pharma Inc | Métodos para replicar un cultivo celular de producción de eculizumab a gran escala |
| FR3030515B1 (fr) * | 2014-12-23 | 2017-01-20 | Galderma Res & Dev | Nouveaux composes antagonistes des recepteurs cxcr1 et cxcr2 aux chimiokines, et leur utilisation dans le traitement de pathologies mediees par des chimiokines |
| JP2018520139A (ja) | 2015-06-26 | 2018-07-26 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | エクリズマブまたはエクリズマブバリアントでのワクチン接種に従って患者を処置するための方法 |
| JP7121722B2 (ja) | 2016-04-04 | 2022-08-18 | ケモセントリックス，インコーポレイティド | 可溶性Ｃ５ａＲアンタゴニスト |
| ES2893769T3 (es) * | 2017-04-03 | 2022-02-10 | Inflarx Gmbh | Tratamiento de enfermedades inflamatorias con inhibidores de la actividad de C5a |
| US10376595B2 (en) * | 2017-04-03 | 2019-08-13 | Inflarx Gmbh | Treatment of inflammatory diseases with inhibitors of C5a activity |
| CN119874606A (zh) | 2019-03-11 | 2025-04-25 | 因弗拉克斯有限责任公司 | 作为C5a受体调节剂的稠合哌啶基双环和相关化合物 |
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- 2018-01-03 CA CA3058023A patent/CA3058023A1/en active Pending
- 2018-01-03 PL PL18701250T patent/PL3411400T3/pl unknown
- 2018-06-13 US US16/007,634 patent/US11273225B2/en active Active
- 2018-09-24 CL CL2018002698A patent/CL2018002698A1/es unknown
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2019
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2022
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2824998C2 (ru) * | 2018-11-30 | 2024-08-19 | Кемосентрикс, Инк. | Лекарственные формы в виде капсул |
| RU2824998C9 (ru) * | 2018-11-30 | 2025-04-21 | Кемосентрикс, Инк. | Лекарственные формы в виде капсул |
Also Published As
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| TWI826364B (zh) | 2023-12-21 |
| EP3411400A1 (en) | 2018-12-12 |
| AU2018249310A1 (en) | 2019-10-17 |
| ES2893769T3 (es) | 2022-02-10 |
| SG11201807998WA (en) | 2018-12-28 |
| JP2022176946A (ja) | 2022-11-30 |
| KR20190138806A (ko) | 2019-12-16 |
| IL261809B2 (en) | 2024-04-01 |
| JP2020515643A (ja) | 2020-05-28 |
| US20180282425A1 (en) | 2018-10-04 |
| EP3411400B1 (en) | 2021-09-22 |
| IL261809A (en) | 2018-11-29 |
| WO2018184739A1 (en) | 2018-10-11 |
| IL261809B1 (en) | 2023-12-01 |
| PL3411400T3 (pl) | 2021-12-20 |
| DK3411400T3 (da) | 2021-10-11 |
| MX2019011825A (es) | 2020-12-11 |
| EP4272821A3 (en) | 2024-01-03 |
| EP3978523A1 (en) | 2022-04-06 |
| CN111108118A (zh) | 2020-05-05 |
| TW201836641A (zh) | 2018-10-16 |
| EP4272821A2 (en) | 2023-11-08 |
| CL2018002698A1 (es) | 2018-12-07 |
| ZA201906485B (en) | 2021-08-25 |
| TW202348249A (zh) | 2023-12-16 |
| US11273225B2 (en) | 2022-03-15 |
| JP7486415B2 (ja) | 2024-05-17 |
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