CA3052739A1 - Nouvelles vesicules extracellulaires anti-angiogeniques - Google Patents

Nouvelles vesicules extracellulaires anti-angiogeniques Download PDF

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Publication number
CA3052739A1
CA3052739A1 CA3052739A CA3052739A CA3052739A1 CA 3052739 A1 CA3052739 A1 CA 3052739A1 CA 3052739 A CA3052739 A CA 3052739A CA 3052739 A CA3052739 A CA 3052739A CA 3052739 A1 CA3052739 A1 CA 3052739A1
Authority
CA
Canada
Prior art keywords
evs
mscs
anyone
angiogenesis
msc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3052739A
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English (en)
Inventor
Antonella Viola
Maurizio Muraca
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fondazione Citta Della Speranza - Onlus
Universita degli Studi di Padova
Original Assignee
Fondazione Citta Della Speranza - Onlus
Universita degli Studi di Padova
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Fondazione Citta Della Speranza - Onlus, Universita degli Studi di Padova filed Critical Fondazione Citta Della Speranza - Onlus
Publication of CA3052739A1 publication Critical patent/CA3052739A1/fr
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention concerne de nouvelles vésicules extracellulaires (vésicules extracellulaires, VE) anti-angiogéniques formées à partir de cellules souches/stromales mésenchymateuses (également connues sous le nom de cellules souches mésenchymateuses, CSM). L'invention concerne également l'utilisation desdits VE pour le traitement de maladies caractérisées par une vascularisation accrue, des compositions pharmaceutiques les comprenant et des procédés de préparation desdits VE.
CA3052739A 2016-12-14 2017-12-14 Nouvelles vesicules extracellulaires anti-angiogeniques Pending CA3052739A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IBPCT/IB2016/057608 2016-12-14
PCT/IB2016/057608 WO2018109525A1 (fr) 2016-12-14 2016-12-14 Nouvelles vésicules extracellulaires anti-angiogéniques
PCT/IB2017/057928 WO2018109700A1 (fr) 2016-12-14 2017-12-14 Nouvelles vésicules extracellulaires anti-angiogéniques

Publications (1)

Publication Number Publication Date
CA3052739A1 true CA3052739A1 (fr) 2018-06-21

Family

ID=57755412

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3052739A Pending CA3052739A1 (fr) 2016-12-14 2017-12-14 Nouvelles vesicules extracellulaires anti-angiogeniques

Country Status (5)

Country Link
EP (1) EP3554513A1 (fr)
CN (1) CN110312515B (fr)
AU (1) AU2017374947B2 (fr)
CA (1) CA3052739A1 (fr)
WO (2) WO2018109525A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202111548SA (en) * 2019-04-18 2021-11-29 Agency Science Tech & Res Composition
CN113384597A (zh) * 2020-03-13 2021-09-14 西比曼生物科技(上海)有限公司 含人体细胞衍生的细胞膜外囊泡的雾化吸入制剂、制法及其应用
WO2021207025A1 (fr) * 2020-04-06 2021-10-14 University Of Georgia Research Foundation, Inc Exosomes des cellules mésenchymateuses augmentant la différenciation des lymphocytes t en lymphocytes t régulateurs
EP3909594A1 (fr) * 2020-05-14 2021-11-17 Bernat Soria Escoms Cellules souches mésenchymateuses pour le traitement de covid-19 et autres maladies inflammatoires, auto-immunes et dégénératives
KR102184428B1 (ko) * 2020-05-25 2020-11-30 주식회사 씨케이엑소젠 중배엽줄기세포 유래의 엑소좀 생산방법 및 이로부터 제조된 배양액
TW202346572A (zh) * 2022-05-16 2023-12-01 台灣粒線體應用技術股份有限公司 用於減緩口腔損傷的組合物、其用途及其製備方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8685728B2 (en) * 2008-01-31 2014-04-01 Rutgers The State University Of New Jersey Kit containing stem cells and cytokines for use in attenuating immune responses
KR101640381B1 (ko) * 2008-02-22 2016-07-18 에이전시 포 사이언스, 테크놀로지 앤드 리서치 중간엽 줄기세포 입자
EP2687219A1 (fr) * 2012-07-18 2014-01-22 Universität Duisburg-Essen Utilisation de préparations contenant des exosomes dérivées de cellules souches mésenchymateuses (msc) dans la prévention et le traitement d'états inflammatoires
ES2909752T3 (es) * 2013-08-01 2022-05-10 Swedish Stromabio Ab MSC en el tratamiento de enfermedades pulmonares inflamatorias
WO2015076717A2 (fr) * 2013-11-21 2015-05-28 Isletone Ab Csm utilisées dans le traitement de troubles cardiaques
CN105861430B (zh) * 2016-04-29 2019-07-23 南京大学 一种外泌体、外泌体的制备方法及其在制备治疗脓毒症药物或者制剂中的应用

Also Published As

Publication number Publication date
AU2017374947A1 (en) 2019-08-01
CN110312515A (zh) 2019-10-08
WO2018109525A1 (fr) 2018-06-21
WO2018109700A1 (fr) 2018-06-21
EP3554513A1 (fr) 2019-10-23
AU2017374947B2 (en) 2023-08-24
CN110312515B (zh) 2023-05-16
AU2017374947A8 (en) 2020-01-16

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Effective date: 20220915

EEER Examination request

Effective date: 20220915

EEER Examination request

Effective date: 20220915

EEER Examination request

Effective date: 20220915

EEER Examination request

Effective date: 20220915