CA3051828A1 - Clinical regimen for treating myelodysplastic syndrome with phosphatase inhibitor - Google Patents
Clinical regimen for treating myelodysplastic syndrome with phosphatase inhibitor Download PDFInfo
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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| US201662287858P | 2016-01-27 | 2016-01-27 | |
| US62/287,858 | 2016-01-27 | ||
| PCT/US2017/015237 WO2017132445A1 (en) | 2016-01-27 | 2017-01-27 | Clincal regimen for treating myelodysplastic syndrome with phosphatase inhibitor |
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| CA (1) | CA3051828A1 (enExample) |
| WO (1) | WO2017132445A1 (enExample) |
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| CA2909160C (en) | 2013-04-09 | 2021-05-25 | Lixte Biotechnology, Inc. | Formulations of oxabicycloheptanes and oxabicycloheptenes |
| EP3736275B1 (en) | 2015-05-15 | 2024-07-03 | Lixte Biotechnology, Inc. | Oxabicycloheptane prodrugs for use in treating cancer |
| US20190240290A1 (en) * | 2016-08-04 | 2019-08-08 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Companion diagnostic for combination lenalidomide and erythropoietin treatment |
| JP7246309B2 (ja) | 2016-12-08 | 2023-03-27 | リクスト・バイオテクノロジー，インコーポレイテッド | 免疫応答を調節するためのオキサビシクロヘプタン |
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| US20080267947A1 (en) | 2006-09-07 | 2008-10-30 | Cirrito Thomas P | Cancer therapy with cantharidin and cantharidin analogs |
| CN101662939B (zh) * | 2007-02-06 | 2015-11-25 | 利克斯特生物技术公司 | 氧杂双环庚烷和氧杂双环庚烯，它们的制备及用途 |
| CA2909160C (en) * | 2013-04-09 | 2021-05-25 | Lixte Biotechnology, Inc. | Formulations of oxabicycloheptanes and oxabicycloheptenes |
| US10071094B2 (en) * | 2014-07-24 | 2018-09-11 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Protein phosphatase 2A inhibitors for treating myelodysplastic syndromes |
| EP3191096A4 (en) * | 2014-09-12 | 2018-03-21 | Lixte Biotechnology, Inc. | Human dosing of phosphatase inhibitor |
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2017
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- 2017-01-27 CN CN201780019895.5A patent/CN109475543A/zh active Pending
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|---|---|
| CN109475543A (zh) | 2019-03-15 |
| WO2017132445A8 (en) | 2018-12-20 |
| US20220184066A1 (en) | 2022-06-16 |
| JP6964593B2 (ja) | 2021-11-10 |
| US20220323433A2 (en) | 2022-10-13 |
| EP3407887A4 (en) | 2019-09-25 |
| JP2019507134A (ja) | 2019-03-14 |
| EP3407887A1 (en) | 2018-12-05 |
| US20190111053A1 (en) | 2019-04-18 |
| EP3407887B1 (en) | 2021-09-01 |
| WO2017132445A1 (en) | 2017-08-03 |
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