CA3042158A1 - Rheometer and method for the use thereof - Google Patents
Rheometer and method for the use thereof Download PDFInfo
- Publication number
- CA3042158A1 CA3042158A1 CA3042158A CA3042158A CA3042158A1 CA 3042158 A1 CA3042158 A1 CA 3042158A1 CA 3042158 A CA3042158 A CA 3042158A CA 3042158 A CA3042158 A CA 3042158A CA 3042158 A1 CA3042158 A1 CA 3042158A1
- Authority
- CA
- Canada
- Prior art keywords
- channel
- blood
- reservoir
- cndot
- section
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 title claims abstract description 27
- 210000004369 blood Anatomy 0.000 claims abstract description 90
- 239000008280 blood Substances 0.000 claims abstract description 90
- 239000012530 fluid Substances 0.000 claims abstract description 63
- 238000004891 communication Methods 0.000 claims abstract description 36
- 239000007788 liquid Substances 0.000 claims description 31
- 238000012544 monitoring process Methods 0.000 claims description 12
- 230000003247 decreasing effect Effects 0.000 claims description 7
- 206010053567 Coagulopathies Diseases 0.000 claims description 6
- 230000035602 clotting Effects 0.000 claims description 6
- 230000017531 blood circulation Effects 0.000 claims description 4
- 238000012545 processing Methods 0.000 claims description 4
- 230000001052 transient effect Effects 0.000 claims description 4
- 230000000737 periodic effect Effects 0.000 claims description 3
- 238000012360 testing method Methods 0.000 description 12
- 238000005259 measurement Methods 0.000 description 8
- 238000005086 pumping Methods 0.000 description 5
- 238000000518 rheometry Methods 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 3
- 230000002441 reversible effect Effects 0.000 description 3
- 238000001356 surgical procedure Methods 0.000 description 3
- 206010040047 Sepsis Diseases 0.000 description 2
- 239000003146 anticoagulant agent Substances 0.000 description 2
- 229940127219 anticoagulant drug Drugs 0.000 description 2
- 230000010100 anticoagulation Effects 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000002572 peristaltic effect Effects 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 238000010079 rubber tapping Methods 0.000 description 2
- 238000012935 Averaging Methods 0.000 description 1
- 206010018910 Haemolysis Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241000270295 Serpentes Species 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 230000003466 anti-cipated effect Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 239000010836 blood and blood product Substances 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000000701 coagulant Substances 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000008588 hemolysis Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003534 oscillatory effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
- G01N11/02—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material
- G01N11/04—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material through a restricted passage, e.g. tube, aperture
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
- G01N11/02—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material
- G01N11/04—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material through a restricted passage, e.g. tube, aperture
- G01N11/08—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material through a restricted passage, e.g. tube, aperture by measuring pressure required to produce a known flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
- A61B5/02028—Determining haemodynamic parameters not otherwise provided for, e.g. cardiac contractility or left ventricular ejection fraction
- A61B5/02035—Determining blood viscosity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
- G01N11/02—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/4905—Determining clotting time of blood
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/491—Blood by separating the blood components
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Ecology (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Surgery (AREA)
- Physiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Saccharide Compounds (AREA)
- Measuring Volume Flow (AREA)
- External Artificial Organs (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1619337.7A GB2555870A (en) | 2016-11-15 | 2016-11-15 | Rheometer and method for the use thereof |
| GB1619337.7 | 2016-11-15 | ||
| PCT/GB2017/053393 WO2018091869A1 (en) | 2016-11-15 | 2017-11-10 | Rheometer and method for the use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3042158A1 true CA3042158A1 (en) | 2018-05-24 |
Family
ID=60331660
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3042158A Pending CA3042158A1 (en) | 2016-11-15 | 2017-11-10 | Rheometer and method for the use thereof |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11378507B2 (enExample) |
| EP (1) | EP3542143B1 (enExample) |
| JP (1) | JP7065849B2 (enExample) |
| KR (1) | KR102486093B1 (enExample) |
| CN (1) | CN110121641B (enExample) |
| AU (2) | AU2017361981B2 (enExample) |
| CA (1) | CA3042158A1 (enExample) |
| GB (1) | GB2555870A (enExample) |
| IL (1) | IL266403B2 (enExample) |
| WO (1) | WO2018091869A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6759372B2 (ja) * | 2019-01-21 | 2020-09-23 | キユーピー株式会社 | 非ニュートン流体のレオロジー特性値を得る方法及び装置 |
| US11747252B2 (en) * | 2020-10-09 | 2023-09-05 | Biofluid Technology, Inc. | Rapid profile viscometer devices and methods |
| WO2025099292A1 (en) * | 2023-11-09 | 2025-05-15 | Analytical Technology and Control Ltd | Haematology apparatus |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2218803A5 (enExample) * | 1973-02-19 | 1974-09-13 | Daillet Ets | |
| DE3230246C2 (de) * | 1982-08-13 | 1985-06-27 | Kiesewetter, Holger, Dr., 5100 Aachen | Vorrichtung zur Bestimmung der Viskosität von Flüssigkeiten, insbesondere des Blutplasmas |
| US4884577A (en) * | 1984-10-31 | 1989-12-05 | Merrill Edward Wilson | Process and apparatus for measuring blood viscosity directly and rapidly |
| JPH0654287B2 (ja) * | 1986-02-21 | 1994-07-20 | 日本鋼管株式会社 | パイプラインにおける非ニユ−トン性の測定装置 |
| WO1987007128A1 (en) * | 1986-05-30 | 1987-12-03 | Kdl Technologies, Inc. | Apparatus and method for measuring native mammalian blood viscosity |
| DE3781677T2 (de) * | 1986-10-17 | 1993-04-01 | Baxter Int | Verfahren und vorrichtung zur bestimmung von haematokrit in einem system zur bearbeitung von blutbestandteilen. |
| DE3921841A1 (de) * | 1989-07-03 | 1991-01-10 | Goettfert Werkstoff Pruefmasch | Echtzeit-kapillarrheometer-anordnung |
| US6402703B1 (en) * | 1997-08-28 | 2002-06-11 | Visco Technologies, Inc. | Dual riser/single capillary viscometer |
| DE19848687B4 (de) * | 1998-10-22 | 2007-10-18 | Thermo Electron (Karlsruhe) Gmbh | Verfahren und Vorrichtung zur simultanen Ermittlung von Scher- und Dehnviskosität |
| DE19958489A1 (de) * | 1999-12-04 | 2001-06-21 | Dupont Performance Coatings | Verfahren und Vorrichtung zur Scherbelastung flüssiger Medien, insbesondere Überzugsmittel |
| US6575019B1 (en) * | 2000-01-14 | 2003-06-10 | Chandler Engineering Company Llc | Reciprocating drive/pump system and reciprocating capillary viscometer utilizing same |
| US6681616B2 (en) * | 2000-02-23 | 2004-01-27 | Caliper Technologies Corp. | Microfluidic viscometer |
| US6898963B2 (en) * | 2003-10-24 | 2005-05-31 | Halliburton Energy Services, Inc. | Apparatus and method for measuring viscosity |
| US20050213427A1 (en) * | 2004-03-23 | 2005-09-29 | Steckle Warren P Jr | Mixing utility, liquid viscometric apparatus |
| US7188515B2 (en) * | 2004-09-24 | 2007-03-13 | The Regents Of The University Of Michigan | Nanoliter viscometer for analyzing blood plasma and other liquid samples |
| JP2007271323A (ja) * | 2006-03-30 | 2007-10-18 | Chisso Corp | 装置 |
| GB0703004D0 (en) * | 2007-02-15 | 2007-03-28 | Uws Ventures Ltd | Apparatus and method for measuring rheological properties of blood |
| DE102007015136A1 (de) * | 2007-03-29 | 2008-10-02 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Scherstress-Applikation |
| US20100260391A1 (en) * | 2007-11-28 | 2010-10-14 | Konica Minolta Opto, Inc. | Blood fluidity measurement system and blood fluidity measurement method |
| PE20121270A1 (es) * | 2009-07-30 | 2012-10-07 | Sgs North America Inc | Analisis de presion-volumen-temperatura de fluidos presurizados |
| GB2474859A (en) | 2009-10-28 | 2011-05-04 | Haemair Ltd | Rheometer |
| PE20121723A1 (es) * | 2009-12-18 | 2012-12-11 | Entegrion Inc | Dispositivo portatil de monitorizacion de la coagulacion y metodo de evaluacion de la respuesta de coagulacion |
| KR101215353B1 (ko) * | 2011-03-03 | 2012-12-26 | 광주과학기술원 | 유체 점도 측정 장치 및 점도 측정 방법 |
| GB201109203D0 (en) * | 2011-06-01 | 2011-07-13 | Carclo Technical Plastics Ltd | Fluid flow control |
| BR112014003425B1 (pt) * | 2011-08-17 | 2020-12-15 | Flow Forward Medical, Inc | Sistema de bomba centrífuga de sangue |
| US9594023B2 (en) * | 2011-12-05 | 2017-03-14 | Sony Corporation | Measurement apparatus and measurement method |
| KR101816933B1 (ko) | 2012-03-21 | 2018-01-09 | 고려대학교 산학협력단 | 바이오 센서 및 그의 작동방법 |
| WO2014031639A1 (en) * | 2012-08-20 | 2014-02-27 | The United States Of America, As Represented By The Secretary, Department Of Health And Humain Services | Capillary viscometer and multiscale pressure differential measuring device |
| CN203785990U (zh) * | 2014-04-19 | 2014-08-20 | 李翠萍 | 一种新型血液流变仪 |
| JP2016140433A (ja) | 2015-01-30 | 2016-08-08 | 泉工医科工業株式会社 | スピーチバルブ |
| KR101580644B1 (ko) * | 2015-02-03 | 2015-12-28 | 포항공과대학교 산학협력단 | 유동 혈액 측정 장치 |
| EP3459460A4 (en) * | 2016-05-18 | 2020-01-29 | Terumo Kabushiki Kaisha | BLOOD INSPECTION SYSTEM AND BLOOD INSPECTION SYSTEM CONTROL METHOD |
-
2016
- 2016-11-15 GB GB1619337.7A patent/GB2555870A/en not_active Withdrawn
-
2017
- 2017-11-10 AU AU2017361981A patent/AU2017361981B2/en active Active
- 2017-11-10 JP JP2019524941A patent/JP7065849B2/ja active Active
- 2017-11-10 CA CA3042158A patent/CA3042158A1/en active Pending
- 2017-11-10 US US16/346,854 patent/US11378507B2/en active Active
- 2017-11-10 EP EP17798294.9A patent/EP3542143B1/en active Active
- 2017-11-10 IL IL266403A patent/IL266403B2/en unknown
- 2017-11-10 CN CN201780070647.3A patent/CN110121641B/zh active Active
- 2017-11-10 KR KR1020197017256A patent/KR102486093B1/ko active Active
- 2017-11-10 WO PCT/GB2017/053393 patent/WO2018091869A1/en not_active Ceased
-
2022
- 2022-06-23 AU AU2022204406A patent/AU2022204406B2/en active Active
- 2022-07-01 US US17/856,250 patent/US11879821B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US11378507B2 (en) | 2022-07-05 |
| IL266403B (en) | 2022-11-01 |
| US20190317000A1 (en) | 2019-10-17 |
| IL266403B2 (en) | 2023-03-01 |
| CN110121641A (zh) | 2019-08-13 |
| BR112019009718A2 (pt) | 2019-08-13 |
| AU2017361981A1 (en) | 2019-05-23 |
| EP3542143C0 (en) | 2023-09-20 |
| JP2019536027A (ja) | 2019-12-12 |
| EP3542143B1 (en) | 2023-09-20 |
| CN110121641B (zh) | 2022-11-29 |
| AU2022204406A1 (en) | 2022-07-14 |
| KR20190085055A (ko) | 2019-07-17 |
| GB2555870A (en) | 2018-05-16 |
| EP3542143A1 (en) | 2019-09-25 |
| AU2022204406B2 (en) | 2024-05-23 |
| AU2017361981B2 (en) | 2022-03-24 |
| JP7065849B2 (ja) | 2022-05-12 |
| US11879821B2 (en) | 2024-01-23 |
| WO2018091869A1 (en) | 2018-05-24 |
| IL266403A (en) | 2019-06-30 |
| US20220404255A1 (en) | 2022-12-22 |
| KR102486093B1 (ko) | 2023-01-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20220929 |
|
| EEER | Examination request |
Effective date: 20220929 |
|
| EEER | Examination request |
Effective date: 20220929 |