CA3039510A1 - Immunogenic arginase peptides - Google Patents

Immunogenic arginase peptides Download PDF

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Publication number
CA3039510A1
CA3039510A1 CA3039510A CA3039510A CA3039510A1 CA 3039510 A1 CA3039510 A1 CA 3039510A1 CA 3039510 A CA3039510 A CA 3039510A CA 3039510 A CA3039510 A CA 3039510A CA 3039510 A1 CA3039510 A1 CA 3039510A1
Authority
CA
Canada
Prior art keywords
seq
arginase
peptide
arg
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3039510A
Other languages
English (en)
French (fr)
Inventor
Mads Hald Andersen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IO Biotech ApS
Original Assignee
IO Biotech ApS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IO Biotech ApS filed Critical IO Biotech ApS
Publication of CA3039510A1 publication Critical patent/CA3039510A1/en
Pending legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y305/00Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/03Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amidines (3.5.3)
    • C12Y305/03001Arginase (3.5.3.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001154Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA3039510A 2016-10-07 2017-10-06 Immunogenic arginase peptides Pending CA3039510A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16192794 2016-10-07
EP16192794.2 2016-10-07
PCT/EP2017/075443 WO2018065563A1 (en) 2016-10-07 2017-10-06 Immunogenic arginase peptides

Publications (1)

Publication Number Publication Date
CA3039510A1 true CA3039510A1 (en) 2018-04-12

Family

ID=57123856

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3039510A Pending CA3039510A1 (en) 2016-10-07 2017-10-06 Immunogenic arginase peptides

Country Status (19)

Country Link
US (3) US10858642B2 (cg-RX-API-DMAC7.html)
EP (2) EP4406613A3 (cg-RX-API-DMAC7.html)
JP (1) JP7211938B2 (cg-RX-API-DMAC7.html)
KR (1) KR102674521B1 (cg-RX-API-DMAC7.html)
CN (1) CN109890399A (cg-RX-API-DMAC7.html)
AU (1) AU2017341112B2 (cg-RX-API-DMAC7.html)
CA (1) CA3039510A1 (cg-RX-API-DMAC7.html)
DK (1) DK3522905T3 (cg-RX-API-DMAC7.html)
ES (1) ES2992031T3 (cg-RX-API-DMAC7.html)
FI (1) FI3522905T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20241486T1 (cg-RX-API-DMAC7.html)
HU (1) HUE069077T2 (cg-RX-API-DMAC7.html)
IL (1) IL265805B2 (cg-RX-API-DMAC7.html)
LT (1) LT3522905T (cg-RX-API-DMAC7.html)
MX (1) MX2019003970A (cg-RX-API-DMAC7.html)
PL (1) PL3522905T3 (cg-RX-API-DMAC7.html)
PT (1) PT3522905T (cg-RX-API-DMAC7.html)
SI (1) SI3522905T1 (cg-RX-API-DMAC7.html)
WO (1) WO2018065563A1 (cg-RX-API-DMAC7.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018065563A1 (en) 2016-10-07 2018-04-12 Herlev Hospital Immunogenic arginase peptides
GB201815549D0 (en) * 2018-09-24 2018-11-07 Io Biotech Aps Arginase1 polypeptides
GB201818576D0 (en) * 2018-11-14 2018-12-26 Io Biotech Aps Arginase 2 polypeptides
GB201912030D0 (en) * 2019-08-21 2019-10-02 Cancer Research Tech Ltd Binding molecules
US20250161422A1 (en) 2022-02-24 2025-05-22 Io Biotech Aps Arginase 2 vaccine
US20250327041A1 (en) 2022-02-24 2025-10-23 Io Biotech Aps Nucleotide delivery of cancer therapy

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US58767A (en) 1866-10-16 John brougjbton
US5554372A (en) 1986-09-22 1996-09-10 Emory University Methods and vaccines comprising surface-active copolymers
US5780286A (en) 1996-03-14 1998-07-14 Smithkline Beecham Corporation Arginase II
US20110111424A1 (en) 2001-06-21 2011-05-12 Cell Signaling Technology, Inc. Analysis of ubiquitinated polypeptides
AU2002353934A1 (en) 2001-10-31 2003-05-12 Oxford Glycosciences (Uk) Ltd. Biomarkers of liver function
CA2586048C (en) * 2004-10-29 2014-03-11 Gregg A. Howe Protection against herbivores
EP3064579B1 (en) 2008-10-31 2020-09-30 AERase, Inc. Pharmaceutical compositions and medical uses of engineered human arginases
EP2449102A4 (en) * 2009-06-29 2013-01-02 George Georgiou ARGINASE FORMULATIONS AND METHODS
CN106456723B (zh) 2014-04-29 2021-03-09 康达医药科技有限公司 采用精氨酸酶i调节免疫系统的方法和组合物
GB201501017D0 (en) 2014-12-23 2015-03-04 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers
WO2018065563A1 (en) 2016-10-07 2018-04-12 Herlev Hospital Immunogenic arginase peptides
CN109890838A (zh) * 2016-10-27 2019-06-14 Io生物技术公司 新的pdl2化合物

Also Published As

Publication number Publication date
IL265805B2 (en) 2024-08-01
MX2019003970A (es) 2019-12-05
JP7211938B2 (ja) 2023-01-24
KR20190077381A (ko) 2019-07-03
KR102674521B1 (ko) 2024-06-11
PL3522905T3 (pl) 2025-01-07
AU2017341112B2 (en) 2024-06-27
EP3522905B1 (en) 2024-09-25
ES2992031T3 (es) 2024-12-05
IL265805A (en) 2019-06-30
US20210139877A1 (en) 2021-05-13
EP4406613A3 (en) 2024-10-23
FI3522905T3 (fi) 2024-10-31
EP4406613A2 (en) 2024-07-31
US20190338270A1 (en) 2019-11-07
US20240167013A1 (en) 2024-05-23
SI3522905T1 (sl) 2025-02-28
US11981944B2 (en) 2024-05-14
HUE069077T2 (hu) 2025-02-28
WO2018065563A1 (en) 2018-04-12
EP3522905A1 (en) 2019-08-14
AU2017341112A1 (en) 2019-05-02
IL265805B1 (en) 2024-04-01
JP2019537562A (ja) 2019-12-26
HRP20241486T1 (hr) 2025-01-03
PT3522905T (pt) 2024-10-02
LT3522905T (lt) 2024-11-11
US10858642B2 (en) 2020-12-08
CN109890399A (zh) 2019-06-14
DK3522905T3 (da) 2024-10-21

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20201207

FZDC Discontinued application reinstated

Effective date: 20211217

FZDC Discontinued application reinstated

Effective date: 20211217

EEER Examination request

Effective date: 20220829

EEER Examination request

Effective date: 20220829

EEER Examination request

Effective date: 20220829

EEER Examination request

Effective date: 20220829