CA3037190A1 - Methods of nucleic acid sample preparation for analysis of cell-free dna - Google Patents
Methods of nucleic acid sample preparation for analysis of cell-free dna Download PDFInfo
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- CA3037190A1 CA3037190A1 CA3037190A CA3037190A CA3037190A1 CA 3037190 A1 CA3037190 A1 CA 3037190A1 CA 3037190 A CA3037190 A CA 3037190A CA 3037190 A CA3037190 A CA 3037190A CA 3037190 A1 CA3037190 A1 CA 3037190A1
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- C12N15/1096—Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
- C12Q1/6855—Ligating adaptors
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- C12Q2549/00—Reactions characterised by the features used to influence the efficiency or specificity
- C12Q2549/10—Reactions characterised by the features used to influence the efficiency or specificity the purpose being that of reducing false positive or false negative signals
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| EP3512965C0 (en) | 2024-03-13 |
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