CA3036299C - LACTATE DERIVATIVE LABELED [18F] AS A POSITRON EMISSION TOMOGRAPHY RADIOTRACER - Google Patents

LACTATE DERIVATIVE LABELED [18F] AS A POSITRON EMISSION TOMOGRAPHY RADIOTRACER

Info

Publication number
CA3036299C
CA3036299C CA3036299A CA3036299A CA3036299C CA 3036299 C CA3036299 C CA 3036299C CA 3036299 A CA3036299 A CA 3036299A CA 3036299 A CA3036299 A CA 3036299A CA 3036299 C CA3036299 C CA 3036299C
Authority
CA
Canada
Prior art keywords
lactate
derivative
lactate derivative
labelled
pet radiotracer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3036299A
Other languages
English (en)
French (fr)
Other versions
CA3036299A1 (en
Inventor
Pierre Sonveaux
Daniel Labar
Hee Vincent Van
Gwenael Dehon
Raphael Frederick
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite Catholique de Louvain UCL
Original Assignee
Universite Catholique de Louvain UCL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite Catholique de Louvain UCL filed Critical Universite Catholique de Louvain UCL
Publication of CA3036299A1 publication Critical patent/CA3036299A1/en
Application granted granted Critical
Publication of CA3036299C publication Critical patent/CA3036299C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computed tomography [CT]
    • A61B6/037—Emission tomography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/52—Devices using data or image processing specially adapted for radiation diagnosis
    • A61B6/5211—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data
    • A61B6/5217—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data extracting a diagnostic or physiological parameter from medical diagnostic data
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/001—Acyclic or carbocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
    • C07C59/115—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups containing halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Physiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nuclear Medicine (AREA)
CA3036299A 2016-09-09 2017-09-08 LACTATE DERIVATIVE LABELED [18F] AS A POSITRON EMISSION TOMOGRAPHY RADIOTRACER Active CA3036299C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16188093.5 2016-09-09
EP16188093.5A EP3293167A1 (de) 2016-09-09 2016-09-09 [18f]-markiertes lactatderivat als pet-radiotracer
PCT/EP2017/072582 WO2018046662A1 (en) 2016-09-09 2017-09-08 [18f]-labelled lactate derivative as pet radiotracer

Publications (2)

Publication Number Publication Date
CA3036299A1 CA3036299A1 (en) 2018-03-15
CA3036299C true CA3036299C (en) 2025-05-06

Family

ID=56920550

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3036299A Active CA3036299C (en) 2016-09-09 2017-09-08 LACTATE DERIVATIVE LABELED [18F] AS A POSITRON EMISSION TOMOGRAPHY RADIOTRACER

Country Status (10)

Country Link
US (2) US10799470B2 (de)
EP (3) EP3293167A1 (de)
JP (1) JP7036802B2 (de)
CA (1) CA3036299C (de)
DK (1) DK3510007T3 (de)
ES (1) ES2882111T3 (de)
HU (1) HUE056905T2 (de)
PL (1) PL3510007T3 (de)
PT (1) PT3510007T (de)
WO (1) WO2018046662A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3293167A1 (de) * 2016-09-09 2018-03-14 Université Catholique De Louvain [18f]-markiertes lactatderivat als pet-radiotracer
JP7148121B2 (ja) * 2018-08-31 2022-10-05 国立大学法人北海道大学 放射性核種１８ｆの精製方法
CN110483278A (zh) * 2019-08-06 2019-11-22 唐刚华 2,2-二氟-3-18f-氟代丙酸及其合成方法与应用
JP7691997B2 (ja) * 2020-03-27 2025-06-12 ヴィフォー （インターナショナル） リミテッド メチル２－フルオロアクリレートの合成

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4149012A (en) 1974-11-08 1979-04-10 Merck & Co., Inc. Synthesis of racemic 3-fluoro-alanine and its salts
SE7511733L (sv) 1974-11-08 1976-05-10 Merck & Co Inc Syntes av recemisk 3-fluoro-alanin och salter derav, samt mellanprodukt i denna syntes
JP4611017B2 (ja) 2002-04-30 2011-01-12 エモリー ユニバーシティー 腫瘍画像化化合物
AU2010208062B2 (en) 2009-01-29 2014-07-24 Kodiscovery, Llc Compositions and methods for the treatment of cancer
EP3293167A1 (de) * 2016-09-09 2018-03-14 Université Catholique De Louvain [18f]-markiertes lactatderivat als pet-radiotracer

Also Published As

Publication number Publication date
EP3510007B1 (de) 2021-07-07
JP2019536735A (ja) 2019-12-19
US20200405667A1 (en) 2020-12-31
CA3036299A1 (en) 2018-03-15
PT3510007T (pt) 2021-07-26
EP3293167A1 (de) 2018-03-14
HUE056905T2 (hu) 2022-04-28
DK3510007T3 (en) 2021-08-02
EP3510007A1 (de) 2019-07-17
PL3510007T3 (pl) 2021-11-08
US20190255002A1 (en) 2019-08-22
US11260036B2 (en) 2022-03-01
EP3925944A1 (de) 2021-12-22
JP7036802B2 (ja) 2022-03-15
ES2882111T3 (es) 2021-12-01
US10799470B2 (en) 2020-10-13
WO2018046662A1 (en) 2018-03-15

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