CA3028036A1 - Compounds for treating disorders sensitive to serotoninergic regulation controlled by the 5-ht1a receptors - Google Patents
Compounds for treating disorders sensitive to serotoninergic regulation controlled by the 5-ht1a receptors Download PDFInfo
- Publication number
- CA3028036A1 CA3028036A1 CA3028036A CA3028036A CA3028036A1 CA 3028036 A1 CA3028036 A1 CA 3028036A1 CA 3028036 A CA3028036 A CA 3028036A CA 3028036 A CA3028036 A CA 3028036A CA 3028036 A1 CA3028036 A1 CA 3028036A1
- Authority
- CA
- Canada
- Prior art keywords
- compound
- nmr
- cdci3
- methyl
- amine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/38—Halogen atoms or nitro radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16305769.8A EP3260452A1 (en) | 2016-06-24 | 2016-06-24 | Compounds for treating disorders sensitive to serotoninergic regulation controlled by the 5-ht1a receptors |
| EP16305769.8 | 2016-06-24 | ||
| PCT/EP2017/065585 WO2017220799A1 (en) | 2016-06-24 | 2017-06-23 | Compounds for treating disorders sensitive to serotoninergic regulation controlled by the 5-ht1a receptors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3028036A1 true CA3028036A1 (en) | 2017-12-28 |
Family
ID=56404042
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3028036A Pending CA3028036A1 (en) | 2016-06-24 | 2017-06-23 | Compounds for treating disorders sensitive to serotoninergic regulation controlled by the 5-ht1a receptors |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10562853B2 (https=) |
| EP (2) | EP3260452A1 (https=) |
| JP (1) | JP6935873B2 (https=) |
| CN (1) | CN109563073B (https=) |
| AU (1) | AU2017281742B2 (https=) |
| CA (1) | CA3028036A1 (https=) |
| DK (1) | DK3475268T3 (https=) |
| ES (1) | ES2831853T3 (https=) |
| WO (1) | WO2017220799A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN119874616B (zh) * | 2025-03-28 | 2025-05-30 | 四川美域高生物医药科技有限公司 | 一种有机中间体及其制备方法和应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2702211B1 (fr) * | 1993-03-04 | 1995-06-02 | Pf Medicament | Nouveaux dérivés de la phénoxy-2 éthylamine, leur préparation et leur application en thérapeutique. |
| FR2755967B1 (fr) | 1996-11-21 | 1999-01-29 | Pf Medicament | Derives de la pyridin-2-yl-methylamine, leur procede de preparation et leur application comme medicaments |
| FR2784378B1 (fr) * | 1998-10-09 | 2000-12-29 | Pf Medicament | Nouveaux derives d'aryl-(4-fluoro-4-[(2-pyridin-2-yl- ethylamino)-methyl]-piperidin-1-yl)-methanone, leur procede de preparation et leur utilisation a titre de medicaments |
| EP2058306A1 (en) * | 2007-11-08 | 2009-05-13 | Schwarz Pharma Ag | Heteroaryl-substituted 2-pyridinyl-methylamine derivatives |
| PL395470A1 (pl) * | 2011-06-29 | 2013-01-07 | Adamed Spólka Z Ograniczona Odpowiedzialnoscia | Sulfonamidowe pochodne amin alicyklicznych do leczenia chorób osrodkowego ukladu nerwowego |
-
2016
- 2016-06-24 EP EP16305769.8A patent/EP3260452A1/en not_active Withdrawn
-
2017
- 2017-06-23 CN CN201780038390.3A patent/CN109563073B/zh active Active
- 2017-06-23 DK DK17734043.7T patent/DK3475268T3/da active
- 2017-06-23 ES ES17734043T patent/ES2831853T3/es active Active
- 2017-06-23 US US16/312,847 patent/US10562853B2/en active Active
- 2017-06-23 CA CA3028036A patent/CA3028036A1/en active Pending
- 2017-06-23 AU AU2017281742A patent/AU2017281742B2/en active Active
- 2017-06-23 JP JP2019520488A patent/JP6935873B2/ja active Active
- 2017-06-23 EP EP17734043.7A patent/EP3475268B9/en active Active
- 2017-06-23 WO PCT/EP2017/065585 patent/WO2017220799A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CN109563073A (zh) | 2019-04-02 |
| CN109563073B (zh) | 2021-12-07 |
| ES2831853T3 (es) | 2021-06-09 |
| EP3260452A1 (en) | 2017-12-27 |
| EP3475268B9 (en) | 2021-04-21 |
| DK3475268T3 (da) | 2020-10-26 |
| US20190194132A1 (en) | 2019-06-27 |
| JP2019519615A (ja) | 2019-07-11 |
| WO2017220799A1 (en) | 2017-12-28 |
| EP3475268A1 (en) | 2019-05-01 |
| AU2017281742B2 (en) | 2021-01-07 |
| EP3475268B1 (en) | 2020-08-19 |
| US10562853B2 (en) | 2020-02-18 |
| JP6935873B2 (ja) | 2021-09-15 |
| AU2017281742A1 (en) | 2019-01-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20220609 |
|
| P11 | Amendment of application requested |
Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-P100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: AMENDMENT RECEIVED - RESPONSE TO EXAMINER'S REQUISITION Effective date: 20240803 |
|
| W00 | Other event occurred |
Free format text: ST27 STATUS EVENT CODE: A-2-2-W10-W00-W111 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: CORRESPONDENT DETERMINED COMPLIANT Effective date: 20250106 |
|
| P11 | Amendment of application requested |
Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-P102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: AMENDMENT DETERMINED COMPLIANT Effective date: 20250401 |
|
| P13 | Application amended |
Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P13-X000 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: APPLICATION AMENDED Effective date: 20250401 |
|
| D15 | Examination report completed |
Free format text: ST27 STATUS EVENT CODE: A-2-2-D10-D15-D126 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: EXAMINER'S REPORT Effective date: 20250428 |
|
| MFA | Maintenance fee for application paid |
Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 8TH ANNIV.) - STANDARD Year of fee payment: 8 |
|
| U00 | Fee paid |
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| P11 | Amendment of application requested |
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| W00 | Other event occurred |
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| P11 | Amendment of application requested |
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| P13 | Application amended |
Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P13-X000 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: APPLICATION AMENDED Effective date: 20251020 |