CA3024910A1 - Anti-pad4 autoantibodies as clinical response biomarkers for the treatment of rheumatoid arthritis - Google Patents
Anti-pad4 autoantibodies as clinical response biomarkers for the treatment of rheumatoid arthritis Download PDFInfo
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- CA3024910A1 CA3024910A1 CA3024910A CA3024910A CA3024910A1 CA 3024910 A1 CA3024910 A1 CA 3024910A1 CA 3024910 A CA3024910 A CA 3024910A CA 3024910 A CA3024910 A CA 3024910A CA 3024910 A1 CA3024910 A1 CA 3024910A1
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C—CHEMISTRY; METALLURGY
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Landscapes
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| US201662340560P | 2016-05-24 | 2016-05-24 | |
| US62/340,560 | 2016-05-24 | ||
| PCT/EP2017/062479 WO2017202879A1 (en) | 2016-05-24 | 2017-05-23 | Anti-pad4 autoantibodies as clinical response biomarkers for the treatment of rheumatoid arthritis |
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| CA3024910A1 true CA3024910A1 (en) | 2017-11-30 |
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|---|---|
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| US11613580B2 (en) * | 2016-05-24 | 2023-03-28 | Medimmune Limited | Anti-PAD4 autoantibodies as clinical response biomarkers for the treatment of rheumatoid arthritis |
| EP3924736A1 (en) * | 2019-02-15 | 2021-12-22 | Inova Diagnostics, Inc. | Compositions and methods for diagnosing and assessing rheumatoid arthritis |
| US20210284744A1 (en) | 2020-03-15 | 2021-09-16 | Kiniksa Pharmaceuticals, Ltd. | Treatment of cytokine release syndrome with gm-csf antagonists |
| CN111458522B (zh) * | 2020-04-20 | 2024-01-09 | 杭州英邈生物科技有限公司 | 一种用于检测血浆白细胞介素6天然抗体的检测试剂、试剂盒及其应用 |
| CN111733151B (zh) * | 2020-07-13 | 2021-11-12 | 山东新创生物科技有限公司 | 一种基于padi4作为肿瘤标志物制得的抗原、抗体及应用 |
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| US6818406B2 (en) | 2001-03-23 | 2004-11-16 | Mayo Foundation For Medical Education And Research | Rheumatoid arthritis markers |
| WO2004110244A2 (en) | 2003-05-08 | 2004-12-23 | Vanderbilt University | A gene equation to diagnose rheumatoid arthritis |
| EP1999152B1 (en) | 2006-03-27 | 2012-09-19 | Medimmune Limited | Binding member for gm-csf receptor |
| JP5252339B2 (ja) * | 2007-12-25 | 2013-07-31 | 地方独立行政法人東京都健康長寿医療センター | Ｐａｄ４及び抗ｐａｄ４抗体の測定方法並びに関節リウマチの検出方法 |
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| US20130101611A1 (en) * | 2009-11-25 | 2013-04-25 | The Johns Hopkins University | Citrullination of human peptidylarginine deiminase 4 (pad-4) regulates its function and immunogenicity |
| ES2660776T3 (es) | 2011-10-10 | 2018-03-26 | Medimmune Limited | Tratamiento para la artritis reumatoide |
| US8975033B2 (en) | 2012-11-05 | 2015-03-10 | The Johns Hopkins University | Human autoantibodies specific for PAD3 which are cross-reactive with PAD4 and their use in the diagnosis and treatment of rheumatoid arthritis and related diseases |
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- 2017-05-23 EP EP17727829.8A patent/EP3464358A1/en active Pending
- 2017-05-23 AU AU2017270027A patent/AU2017270027B2/en active Active
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2023
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| AU2017270027A1 (en) | 2018-12-06 |
| AU2017270027B2 (en) | 2024-07-11 |
| US20200317793A1 (en) | 2020-10-08 |
| US11613580B2 (en) | 2023-03-28 |
| EP3464358A1 (en) | 2019-04-10 |
| JP7217631B2 (ja) | 2023-02-03 |
| WO2017202879A1 (en) | 2017-11-30 |
| JP2019523759A (ja) | 2019-08-29 |
| US20230303707A1 (en) | 2023-09-28 |
| MA45112A (fr) | 2019-04-10 |
| JP2023058524A (ja) | 2023-04-25 |
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