CA3022188A1 - Vinylogous phenethylamines as neurotransmitter releasers - Google Patents
Vinylogous phenethylamines as neurotransmitter releasers Download PDFInfo
- Publication number
- CA3022188A1 CA3022188A1 CA3022188A CA3022188A CA3022188A1 CA 3022188 A1 CA3022188 A1 CA 3022188A1 CA 3022188 A CA3022188 A CA 3022188A CA 3022188 A CA3022188 A CA 3022188A CA 3022188 A1 CA3022188 A1 CA 3022188A1
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- CA
- Canada
- Prior art keywords
- optionally substituted
- alkyl
- pharmaceutically acceptable
- alkynyl
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/28—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by unsaturated carbon chains
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
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| PCT/US2017/032143 WO2017197101A1 (en) | 2016-05-12 | 2017-05-11 | Vinylogous phenethylamines as neurotransmitter releasers |
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| US6262124B1 (en) | 1998-10-22 | 2001-07-17 | Gary Maurice Dull | Pharmaceutical compositions and methods for use |
| US6337351B1 (en) | 1998-10-22 | 2002-01-08 | Targacept, Inc. | Pharmaceutical compositions and methods for use |
| US7084154B2 (en) | 2003-02-11 | 2006-08-01 | Pharmacopeia Drug Disclovery, Inc. | 2-(aminomethyl) arylamide analgesics |
| CA2577144C (en) | 2004-09-30 | 2011-06-21 | Boehringer Ingelheim International Gmbh | Alkynyl compounds as non-nucleoside reverse transcriptase inhibitors |
| US7776869B2 (en) | 2004-10-18 | 2010-08-17 | Amgen Inc. | Heteroaryl-substituted alkyne compounds and method of use |
| CL2007002105A1 (es) | 2006-07-21 | 2008-02-22 | Hoffmann La Roche | Compuestos derivados de 2-[3-(3-cianofenoxi)(fenoxi o fenilsulfanil)]-n-fenil acetamida, inhibidores de la transcriptasa inversa del vih; procedimiento de preparacion; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar u |
| CN101686672A (zh) | 2007-05-31 | 2010-03-31 | 塞普拉柯公司 | 苯基取代的环烷胺作为一元胺再摄取抑制剂 |
| WO2010015029A1 (en) * | 2008-08-06 | 2010-02-11 | Gosforth Centre (Holdings) Pty Ltd | Compositions and methods for treating psychiatric disorders |
| JP5699090B2 (ja) | 2008-12-30 | 2015-04-08 | バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | 嚢胞性線維症膜コンダクタンス調節因子のモジュレーター |
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| ES2443154T3 (es) * | 2009-07-16 | 2014-02-18 | Sds Biotech K. K. | Derivados de 4-(3-butinil) aminopirimidina como agentes pesticidas para uso agrícola y hortícola |
| EP2281801B1 (en) * | 2009-07-27 | 2014-01-08 | Crystal Pharma, S.A.U. | Process for obtaining 3,3-diphenylpropylamines |
| CN102883602B (zh) | 2010-02-16 | 2017-07-18 | Uwm研究基金会有限公司 | 降低细菌的毒力的方法 |
| AU2011354895B2 (en) | 2011-01-14 | 2016-05-05 | Sds Biotech K. K. | Agri-horticultural pest control compositions comprising 4- (3-butynyl)aminopyrimidine derivatives |
| EP2760829B1 (en) * | 2011-09-27 | 2016-05-18 | Bristol-Myers Squibb Company | Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors |
| MX2015007796A (es) | 2012-12-17 | 2015-09-04 | Parion Sciences Inc | Derivados de cloro-pirazin carboxamida con actividad bloqueadora sobre los canales de sodio epiteliales. |
| US20160022636A1 (en) | 2013-03-14 | 2016-01-28 | Janssen Pharmaceutica Nv | Physiological ligands for gpr139 |
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Also Published As
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| WO2017197101A1 (en) | 2017-11-16 |
| US10899699B2 (en) | 2021-01-26 |
| EP3455203A1 (en) | 2019-03-20 |
| EP3455203B1 (en) | 2021-09-22 |
| CN109476583A (zh) | 2019-03-15 |
| JP2019520311A (ja) | 2019-07-18 |
| JP7343641B2 (ja) | 2023-09-12 |
| AU2017263457A1 (en) | 2018-11-15 |
| EP3455203A4 (en) | 2019-11-13 |
| JP2022101537A (ja) | 2022-07-06 |
| ES2895773T3 (es) | 2022-02-22 |
| JP7073272B2 (ja) | 2022-05-23 |
| AU2017263457B2 (en) | 2021-07-08 |
| MX2018012687A (es) | 2019-01-31 |
| US20190225573A1 (en) | 2019-07-25 |
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