CA3006793C - Non-small cell lung cancer biomarkers and uses thereof - Google Patents

Non-small cell lung cancer biomarkers and uses thereof Download PDF

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Publication number
CA3006793C
CA3006793C CA3006793A CA3006793A CA3006793C CA 3006793 C CA3006793 C CA 3006793C CA 3006793 A CA3006793 A CA 3006793A CA 3006793 A CA3006793 A CA 3006793A CA 3006793 C CA3006793 C CA 3006793C
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Canada
Prior art keywords
biomarkers
biomarker
individual
nsclc
cancer
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CA3006793A
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English (en)
French (fr)
Other versions
CA3006793A1 (en
Inventor
Michael Riel-Mehan
Alex A.E. Stewart
Rachel M. Ostroff
Stephen Alaric Williams
Edward N. Brody
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Somalogic Operating Co Inc
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Somalogic Inc
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Priority to CA3006793A priority Critical patent/CA3006793C/en
Publication of CA3006793A1 publication Critical patent/CA3006793A1/en
Application granted granted Critical
Publication of CA3006793C publication Critical patent/CA3006793C/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57423Specifically defined cancers of lung
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/60Complex ways of combining multiple protein biomarkers for diagnosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CA3006793A 2011-10-24 2011-10-24 Non-small cell lung cancer biomarkers and uses thereof Active CA3006793C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA3006793A CA3006793C (en) 2011-10-24 2011-10-24 Non-small cell lung cancer biomarkers and uses thereof

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/US2011/057499 WO2013062515A2 (en) 2011-10-24 2011-10-24 Lung cancer biomarkers and uses thereof
CA3006793A CA3006793C (en) 2011-10-24 2011-10-24 Non-small cell lung cancer biomarkers and uses thereof
CA2847188A CA2847188C (en) 2011-10-24 2011-10-24 Non-small cell lung cancer biomarkers and uses thereof

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2847188A Division CA2847188C (en) 2011-10-24 2011-10-24 Non-small cell lung cancer biomarkers and uses thereof

Publications (2)

Publication Number Publication Date
CA3006793A1 CA3006793A1 (en) 2013-05-02
CA3006793C true CA3006793C (en) 2020-02-18

Family

ID=48168748

Family Applications (3)

Application Number Title Priority Date Filing Date
CA3006793A Active CA3006793C (en) 2011-10-24 2011-10-24 Non-small cell lung cancer biomarkers and uses thereof
CA3064363A Active CA3064363C (en) 2011-10-24 2011-10-24 Non-small cell lung cancer biomarkers and uses thereof
CA2847188A Active CA2847188C (en) 2011-10-24 2011-10-24 Non-small cell lung cancer biomarkers and uses thereof

Family Applications After (2)

Application Number Title Priority Date Filing Date
CA3064363A Active CA3064363C (en) 2011-10-24 2011-10-24 Non-small cell lung cancer biomarkers and uses thereof
CA2847188A Active CA2847188C (en) 2011-10-24 2011-10-24 Non-small cell lung cancer biomarkers and uses thereof

Country Status (15)

Country Link
EP (1) EP2771692B1 (forum.php)
JP (1) JP5986638B2 (forum.php)
KR (1) KR101921945B1 (forum.php)
CN (2) CN103890586B (forum.php)
AU (1) AU2011378427B8 (forum.php)
BR (1) BR112014006432B8 (forum.php)
CA (3) CA3006793C (forum.php)
ES (1) ES2674318T3 (forum.php)
IL (2) IL231426A (forum.php)
IN (1) IN2014CN01787A (forum.php)
MX (1) MX355416B (forum.php)
NZ (1) NZ621733A (forum.php)
SG (1) SG11201400375SA (forum.php)
WO (1) WO2013062515A2 (forum.php)
ZA (1) ZA201401476B (forum.php)

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BR112012032537B8 (pt) 2010-07-09 2022-10-18 Somalogic Inc Métodos para diagnosticar se um indivíduo tem ou não câncer de pulmão de não pequenas células, ou para fornecer informações sobre câncer de pulmão de não pequenas células em um indivíduo
CA2910327A1 (en) * 2013-05-09 2014-11-13 Rui Li Method and system for assessing health condition
US10240146B2 (en) 2014-07-30 2019-03-26 President And Fellows Of Harvard College Probe library construction
CN104263723B (zh) * 2014-09-15 2017-06-06 南京医科大学 一种与原发性肺癌辅助诊断相关的低频高外显性遗传标志物及其应用
WO2016094330A2 (en) * 2014-12-08 2016-06-16 20/20 Genesystems, Inc Methods and machine learning systems for predicting the liklihood or risk of having cancer
JP6857185B2 (ja) * 2015-09-11 2021-04-14 アプタマー サイエンス インコーポレイテッドAptamer Sciences Inc. 非小細胞肺癌診断用タンパク質バイオマーカーパネル及びこれを用いた非小細胞肺癌診断方法
EP3372686B1 (en) * 2015-11-05 2020-05-20 BGI Shenzhen Biomarker for detection of lung adenocarcinoma and use thereof
US10731166B2 (en) * 2016-03-18 2020-08-04 Caris Science, Inc. Oligonucleotide probes and uses thereof
KR101853118B1 (ko) * 2016-09-02 2018-04-30 주식회사 바이오인프라생명과학 피험체의 폐암 진단을 위한 복합 바이오마커군, 이를 이용하는 폐암 진단용 키트, 복합 바이오마커군의 정보를 이용하는 방법 및 이를 수행하는 컴퓨팅 시스템
CN110140175A (zh) * 2016-11-08 2019-08-16 哈佛学院院长及董事 基质印迹和清除
EP3589959B1 (en) * 2017-03-01 2022-09-07 Roche Diagnostics GmbH Systems, method and computer-readable medium for classifying a biological sample regarding the presence of an analyte
WO2018218150A1 (en) 2017-05-26 2018-11-29 President And Fellows Of Harvard College Systems and methods for high-throughput image-based screening
CN109116023B (zh) * 2018-06-14 2021-06-04 郑州大学第一附属医院 一种肺癌标志物抗-mmp12自身抗体及其应用
CN109470859A (zh) * 2018-11-04 2019-03-15 华东医院 一种外泌体蛋白作为鉴别肺结节良恶性标志物及其应用
EP3671210A1 (en) * 2018-12-21 2020-06-24 Biosystems International KFT Lung cancer protein epitomic biomarkers
CN113711313A (zh) * 2019-02-15 2021-11-26 佰欧迪塞克斯公司 用于识别手术后处于高复发风险的早期nsclc患者的预测性测试
CN110473167B (zh) * 2019-07-09 2022-06-17 哈尔滨工程大学 一种基于深度学习的尿沉渣图像识别系统及方法
CN112892619B (zh) * 2019-12-04 2022-07-15 香港城市大学深圳研究院 弧形边缘截面的pdms母模、微流控阀和芯片及其制备
KR102613772B1 (ko) * 2021-02-02 2023-12-14 제노마인(주) 폐암 혈액 바이오마커의 검출 방법 및 키트

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US6335170B1 (en) * 1999-02-22 2002-01-01 Torben F. Orntoft Gene expression in bladder tumors
US6596503B1 (en) * 2000-08-18 2003-07-22 East Carolina University Monoclonal antibody DS6, tumor-associated antigen CA6, and methods of use thereof
DE602005024021D1 (de) * 2004-08-10 2010-11-18 Oncotherapy Science Inc GEN ANLN IN VERBINDUNG MIT NICHT-KLEINZELLIGEM LUNGENKREBS UND SEINE WECHSELWIRKUNGEN MIT RhoA
JP2009502115A (ja) * 2005-07-27 2009-01-29 オンコセラピー・サイエンス株式会社 小細胞肺癌の診断方法
US20080305962A1 (en) 2005-07-29 2008-12-11 Ralph Markus Wirtz Methods and Kits for the Prediction of Therapeutic Success, Recurrence Free and Overall Survival in Cancer Therapies
US8445198B2 (en) * 2005-12-01 2013-05-21 Medical Prognosis Institute Methods, kits and devices for identifying biomarkers of treatment response and use thereof to predict treatment efficacy
US8014957B2 (en) * 2005-12-15 2011-09-06 Fred Hutchinson Cancer Research Center Genes associated with progression and response in chronic myeloid leukemia and uses thereof
WO2008046911A2 (en) * 2006-10-20 2008-04-24 Exiqon A/S Novel human micrornas associated with cancer
GB0803192D0 (en) * 2008-02-22 2008-04-02 Mubio Products Bv SCLC biomarker panel
US10359425B2 (en) * 2008-09-09 2019-07-23 Somalogic, Inc. Lung cancer biomarkers and uses thereof
CN102209968B (zh) * 2008-09-09 2016-05-04 私募蛋白质体公司 肺癌生物标记蛋白的捕获剂在制备试剂盒中的用途
US8541170B2 (en) 2008-11-17 2013-09-24 Veracyte, Inc. Methods and compositions of molecular profiling for disease diagnostics
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WO2011100472A1 (en) * 2010-02-10 2011-08-18 The Regents Of The University Of California Salivary transcriptomic and proteomic biomarkers for breast cancer detection
AU2011223789A1 (en) 2010-03-01 2012-09-20 Caris Life Sciences Switzerland Holdings Gmbh Biomarkers for theranostics
CA2795776A1 (en) 2010-04-06 2011-10-13 Caris Life Sciences Luxembourg Holdings, S.A.R.L. Circulating biomarkers for disease

Also Published As

Publication number Publication date
CA3064363A1 (en) 2013-05-02
EP2771692B1 (en) 2018-04-18
MX355416B (es) 2018-04-18
IN2014CN01787A (forum.php) 2015-05-29
IL231426A (en) 2017-06-29
AU2011378427B2 (en) 2015-07-16
WO2013062515A2 (en) 2013-05-02
AU2011378427A1 (en) 2013-05-16
CN106168624B (zh) 2018-03-13
CA2847188C (en) 2020-02-18
BR112014006432B8 (pt) 2022-10-25
BR112014006432B1 (pt) 2021-04-06
AU2011378427B8 (en) 2015-08-27
BR112014006432A2 (pt) 2017-04-04
JP5986638B2 (ja) 2016-09-06
NZ621733A (en) 2015-05-29
CN106168624A (zh) 2016-11-30
CA2847188A1 (en) 2013-05-02
EP2771692A4 (en) 2015-08-26
KR101921945B1 (ko) 2018-11-26
CN103890586A (zh) 2014-06-25
JP2015501154A (ja) 2015-01-15
ES2674318T3 (es) 2018-06-28
CA3006793A1 (en) 2013-05-02
CA3064363C (en) 2022-05-17
SG11201400375SA (en) 2014-04-28
AU2011378427A8 (en) 2015-08-27
IL252163A0 (en) 2017-07-31
IL231426A0 (en) 2014-04-30
EP2771692A2 (en) 2014-09-03
WO2013062515A3 (en) 2014-04-17
MX2014004860A (es) 2014-05-27
KR20140082840A (ko) 2014-07-02
ZA201401476B (en) 2016-06-29
CN103890586B (zh) 2016-06-29

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