CA3006176C - Bifidobacterium longum for treating obesity and associated metabolic disorders - Google Patents

Bifidobacterium longum for treating obesity and associated metabolic disorders Download PDF

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Publication number
CA3006176C
CA3006176C CA3006176A CA3006176A CA3006176C CA 3006176 C CA3006176 C CA 3006176C CA 3006176 A CA3006176 A CA 3006176A CA 3006176 A CA3006176 A CA 3006176A CA 3006176 C CA3006176 C CA 3006176C
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Prior art keywords
strain
formulation
ncimb
obesity
longum
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CA3006176A
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English (en)
French (fr)
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CA3006176A1 (en
Inventor
Barry Kiely
Eileen Frances Murphy
Selena HEALY
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PrecisionBiotics Group Ltd
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Alimentary Health Ltd
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745Bifidobacteria
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135Bacteria or derivatives thereof, e.g. probiotics
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/30Dietetic or nutritional methods, e.g. for losing weight
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00Function of food ingredients
    • A23V2200/30Foods, ingredients or supplements having a functional effect on health
    • A23V2200/32Foods, ingredients or supplements having a functional effect on health having an effect on the health of the digestive tract
    • A23V2200/3204Probiotics, living bacteria to be ingested for action in the digestive tract
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00Function of food ingredients
    • A23V2200/30Foods, ingredients or supplements having a functional effect on health
    • A23V2200/332Promoters of weight control and weight loss
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Immunology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
CA3006176A 2015-12-11 2016-12-09 Bifidobacterium longum for treating obesity and associated metabolic disorders Active CA3006176C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15199660 2015-12-11
EP15199660.0 2015-12-11
PCT/EP2016/080454 WO2017097987A1 (en) 2015-12-11 2016-12-09 Bifidobacterium longum for treating obesity and associated metabolic disorders

Publications (2)

Publication Number Publication Date
CA3006176A1 CA3006176A1 (en) 2017-06-15
CA3006176C true CA3006176C (en) 2023-10-31

Family

ID=55070675

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3006176A Active CA3006176C (en) 2015-12-11 2016-12-09 Bifidobacterium longum for treating obesity and associated metabolic disorders

Country Status (14)

Country Link
US (1) US10973862B2 (enExample)
EP (1) EP3386523B1 (enExample)
JP (1) JP6843140B2 (enExample)
KR (1) KR102819885B1 (enExample)
CN (1) CN109069552B (enExample)
AU (1) AU2016368527B2 (enExample)
BR (1) BR112018011665A2 (enExample)
CA (1) CA3006176C (enExample)
DK (1) DK3386523T3 (enExample)
ES (1) ES2760076T3 (enExample)
MX (1) MX378890B (enExample)
PL (1) PL3386523T3 (enExample)
RU (1) RU2740096C2 (enExample)
WO (1) WO2017097987A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2964480A1 (en) 2014-10-31 2016-05-06 Whole Biome Inc. Methods and compositions relating to microbial treatment and diagnosis of disorders
US11590179B2 (en) 2017-02-28 2023-02-28 Precisionbiotics Group Limited Bifidobacterium longum able to beneficially modulate immune response to respiratory virus infection
WO2019038449A1 (en) 2017-08-25 2019-02-28 University College Cork - National University Of Ireland, Cork USE OF BIFIDOBACTERIUM LONGUM TO TREAT OBESITY AND PERMIT CONTROL OF WEIGHT
WO2019046646A1 (en) 2017-08-30 2019-03-07 Whole Biome Inc. METHODS AND COMPOSITIONS FOR THE TREATMENT OF MICROBIOMA ASSOCIATED DISORDERS
KR102156399B1 (ko) * 2018-04-11 2020-09-16 한국생명공학연구원 비만의 예방 또는 치료 효과를 가지는 신규 비피도박테리움 롱검 균주 또는 락토바실러스 람노서스 균주 및 이의 용도
JP7811843B2 (ja) 2018-07-19 2026-02-06 ペンデュラム セラピューティクス, インコーポレイテッド 微生物生着のための方法および組成物
KR102224072B1 (ko) * 2019-08-19 2021-03-10 주식회사 빙그레 면역 조절능력과 혈중콜레스테롤 감소 능력이 모두 뛰어난 비피도박테리엄 롱검 아종 균주 및 이의 용도
EP4117697A1 (en) 2020-03-13 2023-01-18 PrecisionBiotics Group Limited Bifidobacterium longum
CN113564069B (zh) * 2021-05-28 2023-09-29 中山大学 一种长双歧杆菌、长双歧杆菌胞外多糖及其提取方法和应用
CN115466689B (zh) * 2022-02-09 2023-06-16 中国科学技术大学 用于预防和/或治疗代谢类疾病的益生菌组合物及其应用
BG67720B1 (bg) * 2022-03-18 2025-04-30 "Ел Би Булгарикум" ЕАД Щам bifidobacterium longum ssp. longum и бифидобактериален препарат с хиполипидемичен ефект, противовъзпалителен имуномодулиращ ефект и с намаляващ инсулиновата резистентност ефект
CN115637237B (zh) * 2022-09-07 2024-09-17 辽宁贝克瑞生物科技有限公司 一株长双歧杆菌及其应用
CN119073589A (zh) * 2024-02-07 2024-12-06 君乐宝乳业集团股份有限公司 一种具有促进骨骼健康功能的组合物及其应用
KR102789455B1 (ko) * 2025-02-05 2025-04-04 주식회사 리스큐어바이오사이언시스 체지방 저감, 혈당 개선 및 근육 기능 강화 활성이 우수한 비피도박테리움 롱검 아종 롱검 lbmb322020 균주 및 이를 포함하는 대사성 질환 예방, 개선 또는 치료용 조성물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1974734A1 (en) * 2007-03-28 2008-10-01 Nestec S.A. Probiotics for reduction of risk of obesity
RU2473681C2 (ru) * 2007-03-28 2013-01-27 Элиментари Хелт Лимитед ПРОБИОТИЧЕСКИЙ ШТАММ Bifidobacterium longum, КОМПОЗИЦИЯ, СОДЕРЖАЩАЯ ТАКОЙ ШТАММ, И ЕГО ПРИМЕНЕНИЕ
EP2176299B1 (en) * 2007-05-04 2017-07-05 Alimentary Health Limited Exopolysaccharide from bifidobacterium infantis 35624 (ncimb 41003)
CN102984955B (zh) * 2008-11-11 2015-01-07 营养健康有限公司 长双歧杆菌
EP2308499A1 (en) * 2009-09-30 2011-04-13 Nestec S.A. Bifidobacterium longum ATCC BAA-999 (BL999) and weight control
RU2546251C2 (ru) * 2009-11-11 2015-04-10 Алиментари Хелс Лимитед Пробиотический штамм бифидобактерий
EP3593811A1 (en) * 2012-09-20 2020-01-15 Prothera, Inc. Probiotic compositions and methods for the treatment of obesity and obesity-related conditions

Also Published As

Publication number Publication date
EP3386523B1 (en) 2019-10-09
WO2017097987A1 (en) 2017-06-15
RU2018119287A3 (enExample) 2020-06-30
EP3386523A1 (en) 2018-10-17
RU2018119287A (ru) 2020-01-13
BR112018011665A2 (pt) 2018-12-04
PL3386523T3 (pl) 2020-03-31
RU2740096C2 (ru) 2021-01-11
KR20180083352A (ko) 2018-07-20
CN109069552B (zh) 2023-01-24
KR102819885B1 (ko) 2025-06-12
JP6843140B2 (ja) 2021-03-17
CN109069552A (zh) 2018-12-21
DK3386523T3 (da) 2020-01-06
ES2760076T3 (es) 2020-05-13
MX2018006905A (es) 2018-08-24
US10973862B2 (en) 2021-04-13
JP2018536427A (ja) 2018-12-13
AU2016368527B2 (en) 2023-01-12
MX378890B (es) 2025-03-10
US20190111090A1 (en) 2019-04-18
AU2016368527A1 (en) 2018-07-12
CA3006176A1 (en) 2017-06-15

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