CA3004587A1 - Use of proteasome inhibitors to treat ocular disorders - Google Patents

Use of proteasome inhibitors to treat ocular disorders Download PDF

Info

Publication number
CA3004587A1
CA3004587A1 CA3004587A CA3004587A CA3004587A1 CA 3004587 A1 CA3004587 A1 CA 3004587A1 CA 3004587 A CA3004587 A CA 3004587A CA 3004587 A CA3004587 A CA 3004587A CA 3004587 A1 CA3004587 A1 CA 3004587A1
Authority
CA
Canada
Prior art keywords
group
eye
composition
ocular
proteasome inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA3004587A
Other languages
English (en)
French (fr)
Inventor
Rick Coulon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Accuitis Pharmaceuticals Inc
Original Assignee
Accuitis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Accuitis Pharmaceuticals Inc filed Critical Accuitis Pharmaceuticals Inc
Publication of CA3004587A1 publication Critical patent/CA3004587A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA3004587A 2015-11-06 2016-10-24 Use of proteasome inhibitors to treat ocular disorders Abandoned CA3004587A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562251937P 2015-11-06 2015-11-06
US62/251,937 2015-11-06
PCT/US2016/058402 WO2017078953A1 (en) 2015-11-06 2016-10-24 Use of proteasome inhibitors to treat ocular disorders

Publications (1)

Publication Number Publication Date
CA3004587A1 true CA3004587A1 (en) 2017-05-11

Family

ID=58662653

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3004587A Abandoned CA3004587A1 (en) 2015-11-06 2016-10-24 Use of proteasome inhibitors to treat ocular disorders

Country Status (8)

Country Link
US (1) US20180325854A1 (cg-RX-API-DMAC7.html)
EP (1) EP3370709A4 (cg-RX-API-DMAC7.html)
JP (1) JP2018533629A (cg-RX-API-DMAC7.html)
CN (1) CN108883081A (cg-RX-API-DMAC7.html)
AU (1) AU2016349833A1 (cg-RX-API-DMAC7.html)
CA (1) CA3004587A1 (cg-RX-API-DMAC7.html)
IL (1) IL259153A (cg-RX-API-DMAC7.html)
WO (1) WO2017078953A1 (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110840860A (zh) * 2019-11-22 2020-02-28 国家纳米科学中心 一种纳米药物及其制备方法和应用

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7213891B2 (ja) * 2018-01-30 2023-01-27 ユニベルシテイト ゲント 白内障を処置するのに使用するための組成物
US11278493B2 (en) * 2018-12-10 2022-03-22 EternaTear, Inc. Ophthalmic formulations providing durable ocular lubrication
US20230050398A1 (en) * 2021-08-04 2023-02-16 Harrow Ip, Llc Methods for increasing shelf-life of ophthalmic pharmaceutical compositions
US11471475B1 (en) 2022-03-08 2022-10-18 Ralph P. Stone Ophthalmic suspension vehicles and related methods for pharmaceutical ingredient delivery
US11679078B1 (en) 2022-03-08 2023-06-20 EternaTear, Inc. Ophthalmic formulations and related methods

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770115A (en) * 1996-04-19 1998-06-23 Ppg Industries, Inc. Photochromic naphthopyran compositions of improved fatigue resistance
BR9909329A (pt) * 1998-04-02 2000-12-12 Novartis Ag Método para estabilizar composições farmacêuticas pelo uso especial de um antioxidante
US20070225350A1 (en) * 2004-12-03 2007-09-27 Anderson Kenneth C Compositions and methods for treating neoplastic diseases
EP1895971A4 (en) * 2005-05-20 2012-08-08 Jack L Arbiser PROTEASOME INHIBITORS AND USES THEREOF
BRPI0617809A2 (pt) * 2005-10-24 2011-08-09 Ciba Holding Inc proteção de agentes oxidáveis
AU2007296259A1 (en) * 2006-09-15 2008-03-20 Janssen Pharmaceutica Nv Combinations of class-I specific histone deacetylase inhibitors with proteasome inhibitors
RU2009116247A (ru) * 2006-09-29 2010-11-10 Джонсон Энд Джонсон Вижн Кэа, Инк. (Us) Способы и офтальмологические устройства, применяемые при лечении аллергии глаз
EP2127638A1 (en) * 2008-05-30 2009-12-02 Santen Pharmaceutical Co., Ltd Method and composition for treating ocular hypertension and glaucoma
CN103566049B (zh) * 2012-08-08 2017-08-04 浙江医药股份有限公司新昌制药厂 用于提高眼睛中视黄斑色素密度并预防或治疗年龄相关性视黄斑衰退症的组合物

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110840860A (zh) * 2019-11-22 2020-02-28 国家纳米科学中心 一种纳米药物及其制备方法和应用
CN110840860B (zh) * 2019-11-22 2021-12-31 国家纳米科学中心 一种纳米药物及其制备方法和应用

Also Published As

Publication number Publication date
AU2016349833A1 (en) 2018-05-24
JP2018533629A (ja) 2018-11-15
WO2017078953A1 (en) 2017-05-11
EP3370709A1 (en) 2018-09-12
US20180325854A1 (en) 2018-11-15
IL259153A (en) 2018-06-28
CN108883081A (zh) 2018-11-23
EP3370709A4 (en) 2019-12-18

Similar Documents

Publication Publication Date Title
CA3004587A1 (en) Use of proteasome inhibitors to treat ocular disorders
AU2015257651B2 (en) Compounds for treating ophthalmic diseases and disorders
CA2928969C (en) Compositions and methods for ophthalmic and/or other applications
ES2367804T3 (es) Implantes intraoculares de agonistas del receptor alfa-2 adrenergico para prevenir o reducir las oclusiones vasculares oculares.
ES2326550T3 (es) Uso de un macrolido para restablecer la sensacion corneal.
US20080125406A1 (en) Method for Treating Primary and Secondary Forms of Glaucoma
Hwang et al. A comparative study of topical mitomycin C, cyclosporine, and bevacizumab after primary pterygium surgery
CA2978874C (en) Ocular formulations comprising a glycosaminoglycan and an anesthetic
CN1753683A (zh) 预防和治疗不良眼部病症的眼用制剂
TW201630614A (zh) 無刺激性眼用聚乙烯吡咯啶酮-碘組成物
EP1187611B1 (en) Ophthalmic histamine compositions and uses thereof
KR20240046311A (ko) 수술 후 안구 염증성 병태를 억제시키기 위한 전방내용의, 항―염증성 및 산동성 용액
WO2014066653A1 (en) Ketorolac-containing sustained release intraocular drug delivery systems
US10350223B2 (en) Compositions and methods for treating ocular diseases
Bagnis et al. Antiglaucoma drugs: The role of preservative-free formulations
US20210085696A1 (en) Formulations comprising chelators, permeation enhancers and hydroxyethyl cellulose for treating ophthalmic disorders
Pathengay et al. Acute postoperative endophthalmitis following cataract surgery: a review
Pérez-Sarriegui et al. Phaco-non-penetrating deep sclerectomy in ocular hypertension secondary to dexamethasone intravitreal implant
WO2012047893A2 (en) Use of rifazil and analogues thereof to treat ocular disorders
Petrov et al. Modern trends in the treatment of glaucoma
WO2025090106A1 (en) Compositions and methods for treating neural degeneration in glaucoma and related conditions
US20230064711A1 (en) Compositions, kits and methods for enhancing therapeutic compliance
CN1802151A (zh) 用于治疗病理性眼内血管生成的非甾体类抗炎药制剂
SA06270472B1 (ar) طريقة لمعالجة النوعين الاولي والثانوي للغلوكوما

Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20220426

FZDE Discontinued

Effective date: 20220426