CA2998381A1 - Pathogen detection using next generation sequencing - Google Patents

Pathogen detection using next generation sequencing Download PDF

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Publication number
CA2998381A1
CA2998381A1 CA2998381A CA2998381A CA2998381A1 CA 2998381 A1 CA2998381 A1 CA 2998381A1 CA 2998381 A CA2998381 A CA 2998381A CA 2998381 A CA2998381 A CA 2998381A CA 2998381 A1 CA2998381 A1 CA 2998381A1
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Canada
Prior art keywords
sequence reads
alignment
sample
sequence
reads
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CA2998381A
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English (en)
French (fr)
Inventor
Charles Chiu
Samia NACCACHE
Scot FEDERMAN
Doug STRYKE
Steve Miller
Erik SAMAYOA
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University of California
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University of California
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Publication of CA2998381A1 publication Critical patent/CA2998381A1/en
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    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10Sequence alignment; Homology search

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  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Evolutionary Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CA2998381A 2015-09-21 2016-09-21 Pathogen detection using next generation sequencing Pending CA2998381A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562221574P 2015-09-21 2015-09-21
US62/221,574 2015-09-21
PCT/US2016/052912 WO2017053446A2 (en) 2015-09-21 2016-09-21 Pathogen detection using next generation sequencing

Publications (1)

Publication Number Publication Date
CA2998381A1 true CA2998381A1 (en) 2017-03-30

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ID=58387233

Family Applications (1)

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CA2998381A Pending CA2998381A1 (en) 2015-09-21 2016-09-21 Pathogen detection using next generation sequencing

Country Status (4)

Country Link
US (3) US11515006B2 (de)
EP (1) EP3353696A4 (de)
CA (1) CA2998381A1 (de)
WO (1) WO2017053446A2 (de)

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CN111518711A (zh) * 2019-02-02 2020-08-11 常熟理工学院 一株肠杆菌株及其在联产微生物胞外多糖和2,3-丁二醇中的应用

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US11485969B2 (en) * 2017-04-21 2022-11-01 The Board Of Trustees Of The Leland Stanford Junior University Collector device of environmental exposure for biotic and abiotic agents
CN111527044A (zh) 2017-10-26 2020-08-11 阿尔缇玛基因组学公司 用于序列判定的方法和系统
US11031092B2 (en) * 2017-11-01 2021-06-08 International Business Machines Corporation Taxonomic annotation of variable length metagenomic patterns
CN108220211B (zh) * 2018-04-02 2019-12-31 中国科学院微生物研究所 一株嗜油不动杆菌nmb17及其在植物病害防治中的应用
EP3844298A4 (de) * 2018-08-27 2022-05-18 Idbydna Inc. Verfahren und systeme zur bereitstellung von probenformationen
US11314781B2 (en) * 2018-09-28 2022-04-26 International Business Machines Corporation Construction of reference database accurately representing complete set of data items for faster and tractable classification usage
CN109610008A (zh) * 2018-11-08 2019-04-12 广州华大基因医学检验所有限公司 基于高通量测序的中枢系统感染病原检测文库构建方法、检测方法和试剂盒
CN109504688B (zh) * 2018-12-28 2020-06-12 华南农业大学 ITS1基因在检测白粉病病原Erysiphe alphitoides中的应用
WO2020185790A1 (en) * 2019-03-10 2020-09-17 Ultima Genomics, Inc. Methods and systems for sequence calling
FR3099182B1 (fr) 2019-07-23 2022-11-25 Biomerieux Sa Procédé de détection et de quantification d'une espèce biologique d'intérêt par analyse métagénomique
FR3099183B1 (fr) * 2019-07-23 2022-11-18 Biomerieux Sa Procédé de détection et de quantification d'une espèce biologique d'intérêt par analyse métagénomique, et détermination d'un niveau de confiance associé
FR3099181B1 (fr) * 2019-07-23 2022-11-18 Biomerieux Sa Procédé de détection et de quantification d'une espèce biologique d'intérêt par analyse métagénomique, avec prise en compte d'un calibrateur.
FR3099180B1 (fr) * 2019-07-23 2022-11-25 Biomerieux Sa Procédé de détection et de quantification d'une espèce biologique d'intérêt par analyse métagénomique, comportant l'utilisation d'une espèce de contrôle.
CN114787928A (zh) * 2019-11-12 2022-07-22 雷杰纳荣制药公司 用于鉴定、分类和/或排序遗传序列的方法和系统
WO2021247886A1 (en) * 2020-06-03 2021-12-09 Arc Bio, Llc Systems, methods, and media for classifying genetic sequencing results based on pathogen-specific adaptive thresholds
CN111951895B (zh) * 2020-07-09 2023-12-26 苏州协云基因科技有限公司 基于宏基因组学的病原分析方法、分析装置、设备及存储介质
CN111816245B (zh) * 2020-07-20 2022-09-09 成都博欣医学检验实验室有限公司 结合mNGS和临床知识库的病原微生物检测方法及系统
CN113096737B (zh) * 2021-03-26 2023-10-31 北京源生康泰基因科技有限公司 一种用于对病原体类型进行自动分析的方法及系统
CN113066533B (zh) * 2021-04-02 2023-04-04 欧蒙医学诊断(中国)有限公司 一种mNGS病原体数据分析方法
EP4326297A1 (de) * 2021-04-21 2024-02-28 Rutgers, the State University of New Jersey Verfahren zur analyse von wirts-mikrobiom-interaktionen an einzelzellen und zugehörigen gensignaturen bei krebs
CN113326123B (zh) * 2021-04-30 2024-03-26 杭州绳武科技有限公司 一种基于容器技术的生物信息分析计算系统及方法
US20240266072A1 (en) * 2021-05-21 2024-08-08 Battelle Memorial Institute System and method for genomic analysis of pathogens
WO2022272085A1 (en) * 2021-06-25 2022-12-29 Atossa Therapeutics, Inc. Remote detection of pathogens
CA3223241A1 (en) * 2021-07-02 2023-01-05 Simone OLGIATI Method for determining viral contamination
EP4239638A1 (de) * 2022-03-03 2023-09-06 Ares Trading S.A. Verfahren zum bestimmen viraler verunreinigung
WO2024006744A2 (en) * 2022-06-28 2024-01-04 Foundation Medicine, Inc. Methods and systems for normalizing targeted sequencing data
CN115537462B (zh) * 2022-10-13 2023-08-11 深圳市儿童医院 一种同时检测病原菌和宿主基因表达量的测序方法及在细菌性脑膜炎诊断和预后中的应用
CN117746980A (zh) * 2023-12-18 2024-03-22 广州凯普医学检验所有限公司 一种流感病毒自动化快速分型方法、装置、设备及介质

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EP3144672B1 (de) * 2007-11-21 2018-08-22 Cosmosid Inc. Genomidentifikationssystem
CN102154450B (zh) * 2010-12-23 2014-07-16 深圳华大基因科技有限公司 一种检测肠炎致病菌的方法
WO2012101643A1 (en) * 2011-01-26 2012-08-02 Ramot At Tel-Aviv University Ltd. Detection of infection by a microorganism using small rna sequencing subtraction and assembly
WO2012122522A2 (en) * 2011-03-09 2012-09-13 Washington University Cultured collection of gut microbial community
CA2930597A1 (en) * 2015-05-22 2016-11-22 The University Of British Columbia Methods for the graphical representation of genomic sequence data

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111518711A (zh) * 2019-02-02 2020-08-11 常熟理工学院 一株肠杆菌株及其在联产微生物胞外多糖和2,3-丁二醇中的应用
CN111518711B (zh) * 2019-02-02 2021-12-07 常熟理工学院 一株肠杆菌株及其在联产微生物胞外多糖和2,3-丁二醇中的应用

Also Published As

Publication number Publication date
WO2017053446A2 (en) 2017-03-30
EP3353696A2 (de) 2018-08-01
US20200243161A1 (en) 2020-07-30
WO2017053446A3 (en) 2017-05-04
US11515006B2 (en) 2022-11-29
US20200335177A1 (en) 2020-10-22
US20180203976A1 (en) 2018-07-19
US11380421B2 (en) 2022-07-05
EP3353696A4 (de) 2019-05-29

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