CA2993435A1 - Pathogen-resistant animals having modified cd163 genes - Google Patents
Pathogen-resistant animals having modified cd163 genes Download PDFInfo
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- CA2993435A1 CA2993435A1 CA2993435A CA2993435A CA2993435A1 CA 2993435 A1 CA2993435 A1 CA 2993435A1 CA 2993435 A CA2993435 A CA 2993435A CA 2993435 A CA2993435 A CA 2993435A CA 2993435 A1 CA2993435 A1 CA 2993435A1
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- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
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| PCT/US2015/044113 WO2017023337A1 (en) | 2015-08-06 | 2015-08-06 | Pathogen-resistant animals having modified cd163 genes |
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| DK3331355T3 (en) | 2015-08-06 | 2024-07-08 | Univ Missouri | Porcine reproductive and respiratory syndrome virus (prrsv)-resistant porcine and cells having modified cd163 genes |
| GB201617559D0 (en) * | 2016-10-17 | 2016-11-30 | University Court Of The University Of Edinburgh The | Swine comprising modified cd163 and associated methods |
| WO2019090237A1 (en) * | 2017-11-03 | 2019-05-09 | Genus Plc | Selectively targeted dna edits in livestock |
| US11160260B2 (en) | 2018-04-17 | 2021-11-02 | The Curators Of The University Of Missouri | Methods for protecting porcine fetuses from infection with porcine reproductive and respiratory syndrome virus (PRRSV) |
| BR112020021066A2 (pt) * | 2018-04-17 | 2021-02-17 | The Curators Of The University Of Missouri | método para proteger um feto suíno da infecção com o vírus da síndrome respiratória e reprodutiva suína (prrsv) |
| CN108753832A (zh) * | 2018-04-20 | 2018-11-06 | 中山大学 | 一种利用CRISPR/Cas9编辑大白猪CD163基因的方法 |
| CN108823248A (zh) * | 2018-04-20 | 2018-11-16 | 中山大学 | 一种利用CRISPR/Cas9编辑陆川猪CD163基因的方法 |
| CN112313330A (zh) * | 2018-04-27 | 2021-02-02 | 密苏里大学管理者 | 具有经修饰氨肽酶n(anpep)基因的抗病原体动物 |
| BR112022020072A2 (pt) * | 2020-05-05 | 2022-11-29 | Genus Plc | Genes cd163, células, linhagens de células, par de grnas, complexo crispr, métodos para editar um gene cd163, preparar uma célula, produzir animais e determinar a presença ou ausência de uma sequência editada, embrião, leitão ou porco adulto, iniciador de pcr, sonda de pcr, usos e método de criação de um porco resistente ao prrsv |
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| US20110016546A1 (en) * | 2008-12-04 | 2011-01-20 | Sigma-Aldrich Co. | Porcine genome editing with zinc finger nucleases |
| HUE039793T2 (hu) * | 2011-05-16 | 2019-02-28 | Univ Missouri | Sertés reproduktív és légzési szindróma vírus rezisztens állatok |
| CN104302316A (zh) * | 2012-05-17 | 2015-01-21 | 佐蒂斯有限责任公司 | 在断奶之前对抗猪繁殖与呼吸综合征(prrs)病毒的有效疫苗接种 |
| GB201313235D0 (en) * | 2013-07-24 | 2013-09-04 | Univ Edinburgh | Antiviral Compositions Methods and Animals |
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| KR20230021174A (ko) | 2023-02-13 |
| KR102631856B1 (ko) | 2024-02-01 |
| KR20180033548A (ko) | 2018-04-03 |
| AU2015404563B2 (en) | 2022-11-17 |
| AU2023200913A1 (en) | 2023-04-27 |
| WO2017023337A1 (en) | 2017-02-09 |
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| KR20240017121A (ko) | 2024-02-06 |
| AU2015404563A1 (en) | 2018-02-15 |
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