CA2991529C - Pre-frontal cortex processing disorder, gait and limb impairment treatment - Google Patents

Pre-frontal cortex processing disorder, gait and limb impairment treatment Download PDF

Info

Publication number
CA2991529C
CA2991529C CA2991529A CA2991529A CA2991529C CA 2991529 C CA2991529 C CA 2991529C CA 2991529 A CA2991529 A CA 2991529A CA 2991529 A CA2991529 A CA 2991529A CA 2991529 C CA2991529 C CA 2991529C
Authority
CA
Canada
Prior art keywords
methylphenidate
gait
disorder
dextro
impairment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2991529A
Other languages
English (en)
French (fr)
Other versions
CA2991529A1 (en
Inventor
Bruce Roseman
Gilla Kaplan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GILROSE PHARMACEUTICALS LLC
Original Assignee
GILROSE PHARMACEUTICALS LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US14/793,829 external-priority patent/US9307942B2/en
Priority claimed from US15/075,375 external-priority patent/US9682073B2/en
Application filed by GILROSE PHARMACEUTICALS LLC filed Critical GILROSE PHARMACEUTICALS LLC
Publication of CA2991529A1 publication Critical patent/CA2991529A1/en
Application granted granted Critical
Publication of CA2991529C publication Critical patent/CA2991529C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4458Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA2991529A 2015-07-08 2016-06-14 Pre-frontal cortex processing disorder, gait and limb impairment treatment Active CA2991529C (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US14/793,829 US9307942B2 (en) 2011-05-19 2015-07-08 Treatment for cerebral palsy gait impairment
US14/793,829 2015-07-08
US14/881,516 2015-10-13
US14/881,516 US9333198B2 (en) 2011-05-19 2015-10-13 Treatment for cerebral palsy gait impairment
US14/971,325 US9408838B2 (en) 2011-05-19 2015-12-16 Treatment for cerebral palsy gait impairment
US14/971,325 2015-12-16
US15/075,375 US9682073B2 (en) 2011-05-19 2016-03-21 Pre-frontal cortex processing disorder gait and limb impairments treatment
US15/075,375 2016-03-21
PCT/US2016/037367 WO2017007577A1 (en) 2015-07-08 2016-06-14 Pre-frontal cortex processing disorder, gait and limb impairment treatment

Publications (2)

Publication Number Publication Date
CA2991529A1 CA2991529A1 (en) 2017-01-12
CA2991529C true CA2991529C (en) 2021-01-05

Family

ID=57686013

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2991529A Active CA2991529C (en) 2015-07-08 2016-06-14 Pre-frontal cortex processing disorder, gait and limb impairment treatment

Country Status (6)

Country Link
EP (1) EP3319603B1 (enExample)
JP (2) JP6930969B2 (enExample)
CN (1) CN108025003B (enExample)
CA (1) CA2991529C (enExample)
MX (1) MX2017016910A (enExample)
WO (1) WO2017007577A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2991529C (en) * 2015-07-08 2021-01-05 Gilrose Pharmaceuticals, Llc Pre-frontal cortex processing disorder, gait and limb impairment treatment

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2157880A (en) 1937-01-22 1939-05-09 Electrical Res Prod Inc Recording system
US2507631A (en) 1944-01-19 1950-05-16 Ciba Pharm Prod Inc Pyridine and piperidine compounds and process of making same
US4145083A (en) 1977-06-17 1979-03-20 Urban Frank K Therapeutic chair for cerebral palsy child
US4844075A (en) 1984-01-09 1989-07-04 Pain Suppression Labs, Inc. Transcranial stimulation for the treatment of cerebral palsy
GB9120306D0 (en) 1991-09-24 1991-11-06 Graham Herbert K Method and compositions for the treatment of cerebral palsy
US6355656B1 (en) 1995-12-04 2002-03-12 Celgene Corporation Phenidate drug formulations having diminished abuse potential
US5908850A (en) 1995-12-04 1999-06-01 Celgene Corporation Method of treating attention deficit disorders with d-threo methylphenidate
US6121261A (en) 1997-11-19 2000-09-19 Merck & Co., Inc. Method for treating attention deficit disorder
RU2185106C1 (ru) 2001-07-12 2002-07-20 Свадовский Александр Игоревич Способ нейрохирургического лечения детского церебрального паралича
US7973057B2 (en) * 2003-09-17 2011-07-05 The United States Of America As Represented By The Department Of Health And Human Services Thalidomide analogs
US8952895B2 (en) * 2011-06-03 2015-02-10 Apple Inc. Motion-based device operations
US20050215521A1 (en) 2003-12-22 2005-09-29 Karim Lalji Modafinil combination therapy for improving sleep quality
US20050182097A1 (en) 2003-12-30 2005-08-18 Zeldis Jerome B. Methods and compositions using thalidomide for the treatment and management of central nervous system disorders or diseases
AU2006204699B2 (en) * 2005-01-13 2012-04-26 Sirtris Pharmaceuticals, Inc. Novel compositions for preventing and treating neurodegenerative and blood coagulation disorders
EP2338881A1 (en) 2005-02-23 2011-06-29 Prexa Pharmaceuticals, Inc. Dopamine transporter inhibitors for use in treatment of movement disorders and other CNS indications
CA2686155C (en) * 2006-05-22 2016-11-15 The Board Of Trustees Of The Leland Stanford Junior University Pharmacological treatment of cognitive impairment
EP1985276A1 (en) 2007-04-26 2008-10-29 Merz Pharma GmbH & Co. KGaA Treatment of movement disorders by a combined use of a chemodenervating agent and automated movement therapy
US20110270345A1 (en) 2007-08-11 2011-11-03 Johns Hopkins University Focal noninvasive stimulation of the sensory cortex of a subject with cerebral palsy
MX2011001384A (es) * 2008-08-06 2011-09-27 Gosforth Ct Holdings Pty Ltd Composiciones y metodos para tratar trastornos psiquiatricos.
WO2011011528A1 (en) * 2009-07-23 2011-01-27 Musc Foundation For Research Development Isopropylphenidate for the treatment of attention-deficit/hyperactivity disorder and fatigue-related disorders and conditions
WO2011085256A2 (en) * 2010-01-07 2011-07-14 Vivus, Inc. Treatment of obstructive sleep apnea syndrome with a combination of a carbonic anhydrase inhibitor and an additional active agent
CN102792513A (zh) * 2010-03-01 2012-11-21 波士顿电力公司 具有平均温度及热点回授之热感测器装置
EP2544688B1 (en) * 2010-03-02 2016-09-07 President and Fellows of Harvard College Methods and compositions for treatment of angelman syndrome
US8287903B2 (en) 2011-02-15 2012-10-16 Tris Pharma Inc Orally effective methylphenidate extended release powder and aqueous suspension product
US20140163070A1 (en) 2012-05-17 2014-06-12 Bruce Roseman Treatment for cerebral palsy impaired speech in children
US9682073B2 (en) * 2011-05-19 2017-06-20 Gilrose Pharmaceuticals, Llc Pre-frontal cortex processing disorder gait and limb impairments treatment
US8883815B2 (en) 2011-05-19 2014-11-11 Gilrose Pharmaceuticals, Llc Treatment for cerebral palsy impaired speech in children
WO2012158892A2 (en) * 2011-05-19 2012-11-22 Bruce Roseman A method of treating apraxia of speech in children
KR20130016127A (ko) * 2011-08-04 2013-02-14 의료법인 성광의료재단 외상성 뇌손상의 치료
KR102080154B1 (ko) * 2011-12-08 2020-02-21 아포스-메디컬 앤드 스포츠 테크놀로지즈 엘티디. 신경 장애들을 치료하기 위한 장치
EP2705841A1 (en) * 2012-09-05 2014-03-12 Pharnext Combinations of nootropic agents for treating cognitive dysfunctions
US9305307B2 (en) * 2013-07-15 2016-04-05 Google Inc. Selecting content associated with a collection of entities
ES2719703T3 (es) * 2013-11-08 2019-07-12 Noramco Inc Procedimiento para la preparación de metilfenidato y sus sales farmacéuticas
CA2991529C (en) * 2015-07-08 2021-01-05 Gilrose Pharmaceuticals, Llc Pre-frontal cortex processing disorder, gait and limb impairment treatment

Also Published As

Publication number Publication date
EP3319603A1 (en) 2018-05-16
JP7350794B2 (ja) 2023-09-26
EP3319603A4 (en) 2019-03-13
MX2017016910A (es) 2018-08-15
JP2018521127A (ja) 2018-08-02
CN108025003B (zh) 2021-07-13
JP6930969B2 (ja) 2021-09-01
EP3319603B1 (en) 2021-11-17
WO2017007577A1 (en) 2017-01-12
CA2991529A1 (en) 2017-01-12
CN108025003A (zh) 2018-05-11
JP2021088571A (ja) 2021-06-10

Similar Documents

Publication Publication Date Title
US9408838B2 (en) Treatment for cerebral palsy gait impairment
KR102785448B1 (ko) 신경퇴행성 질병을 위한 치료제
AU2017236177B2 (en) Use of masitinib for treatment of an amyotrophic lateral sclerosis patient subpopulation
WO2014019268A1 (zh) 一种促进神经损伤修复的药物组合物及其应用
US9682073B2 (en) Pre-frontal cortex processing disorder gait and limb impairments treatment
US11102953B2 (en) Pre-frontal cortex processing disorder speech, gait and limb impairments treatment
KR102549684B1 (ko) 신경퇴행성 질병에 대한 치료제
JP7350794B2 (ja) 前頭前皮質プロセシング疾患、歩行及び四肢障害の治療
KR20170131543A (ko) 근위축성 측삭 경화증을 치료하기 위한 비오틴
A. Sackner Whole Body Periodic Acceleration:" Passive Exercise" for Parkinson’s disease
RU2594252C1 (ru) Способ реабилитации больных алкогольной полинейропатией
JP2019517516A (ja) Smaの新規な処置
Lockley et al. Physical management of spasticity
US20090124606A1 (en) Composition for Treatment of Psychosis
Stone et al. VITAMIN B AND E THERAPY IN TABES DORSALIS:(Preliminary Report on the Use of Wheat Germ Oil, Vitamin B Complex and Intraspinal Administration of Thiamin Chloride)
Mandelcorn et al. A preliminary study of the efficacy of ondansetron in the treatment of ataxia, poor balance and incoordination from brain injury
WO2004105756A2 (en) Combination comprising (a) a neuroprotecting agent and (b) an agent binding to gadph and pharmaceutical use thereof
CA2735949C (en) Use of ribose in lessening the clinical symptoms of aberrant firing of neurons
HK1262519A1 (en) New treatment of sma
WO2017111052A1 (ja) 自己免疫疾患治療剤

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20180308