CA2972577A1 - Digital microfluidic dilution apparatus, systems, and related methods - Google Patents

Digital microfluidic dilution apparatus, systems, and related methods Download PDF

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Publication number
CA2972577A1
CA2972577A1 CA2972577A CA2972577A CA2972577A1 CA 2972577 A1 CA2972577 A1 CA 2972577A1 CA 2972577 A CA2972577 A CA 2972577A CA 2972577 A CA2972577 A CA 2972577A CA 2972577 A1 CA2972577 A1 CA 2972577A1
Authority
CA
Canada
Prior art keywords
electrode
droplet
area
electrodes
volume
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2972577A
Other languages
English (en)
French (fr)
Inventor
Andrew Fischer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of CA2972577A1 publication Critical patent/CA2972577A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • B01L3/502792—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics for moving individual droplets on a plate, e.g. by locally altering surface tension
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/089—Virtual walls for guiding liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0427—Electrowetting

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Micromachines (AREA)
  • Accessories For Mixers (AREA)
CA2972577A 2014-12-31 2015-12-21 Digital microfluidic dilution apparatus, systems, and related methods Abandoned CA2972577A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462098679P 2014-12-31 2014-12-31
US62/098,679 2014-12-31
PCT/US2015/067021 WO2016109279A1 (en) 2014-12-31 2015-12-21 Digital microfluidic dilution apparatus, systems, and related methods

Publications (1)

Publication Number Publication Date
CA2972577A1 true CA2972577A1 (en) 2016-07-07

Family

ID=55273514

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2972577A Abandoned CA2972577A1 (en) 2014-12-31 2015-12-21 Digital microfluidic dilution apparatus, systems, and related methods

Country Status (6)

Country Link
US (2) US10369565B2 (https=)
EP (1) EP3240634A1 (https=)
JP (2) JP6622811B2 (https=)
CN (2) CN107249743B (https=)
CA (1) CA2972577A1 (https=)
WO (1) WO2016109279A1 (https=)

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US12364538B2 (en) * 2018-11-05 2025-07-22 Biosense Webster (Israel) Ltd. Indifferent electrode with selectable area
CN109652287B (zh) * 2019-01-03 2021-04-30 京东方科技集团股份有限公司 一种微控基板及其制作方法和微流控芯片
WO2020154642A1 (en) * 2019-01-24 2020-07-30 Fluxergy, Llc Microfluidic device with constant heater uniformity
CN112295616B (zh) * 2020-09-11 2022-03-18 东南大学 一种微液滴混合强化微流控装置
CN114166615A (zh) * 2021-11-22 2022-03-11 南方科技大学 一种数字微流控液滴的稀释方法
CN114534805B (zh) * 2022-02-09 2024-08-06 上海天马微电子有限公司 微流控装置及其驱动方法、制作方法
WO2024050639A1 (en) * 2022-09-09 2024-03-14 Nicoya Lifesciences Inc. Microfluidics device including ganged reservoir configurations and methods of using same

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Also Published As

Publication number Publication date
JP6622811B2 (ja) 2019-12-18
JP2018500573A (ja) 2018-01-11
CN107249743B (zh) 2020-01-10
WO2016109279A1 (en) 2016-07-07
EP3240634A1 (en) 2017-11-08
US20160184823A1 (en) 2016-06-30
JP2020024206A (ja) 2020-02-13
US10369565B2 (en) 2019-08-06
US20190351411A1 (en) 2019-11-21
CN107249743A (zh) 2017-10-13
US11213817B2 (en) 2022-01-04
CN110935496A (zh) 2020-03-31
JP6917425B2 (ja) 2021-08-11

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20170628

FZDE Discontinued

Effective date: 20211221