CA2967037A1 - Anti-acetaminophen antibodies and acetaminophen protein adducts - Google Patents

Anti-acetaminophen antibodies and acetaminophen protein adducts Download PDF

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Publication number
CA2967037A1
CA2967037A1 CA2967037A CA2967037A CA2967037A1 CA 2967037 A1 CA2967037 A1 CA 2967037A1 CA 2967037 A CA2967037 A CA 2967037A CA 2967037 A CA2967037 A CA 2967037A CA 2967037 A1 CA2967037 A1 CA 2967037A1
Authority
CA
Canada
Prior art keywords
acetaminophen
seq
antibody
protein adduct
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA2967037A
Other languages
English (en)
French (fr)
Inventor
Dean W. ROBERTS
Laura James
Jack HINSON
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arkansas Childrens Hospital Research Institute Inc
BioVentures LLC
Original Assignee
Arkansas Childrens Hospital Research Institute Inc
BioVentures LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arkansas Childrens Hospital Research Institute Inc, BioVentures LLC filed Critical Arkansas Childrens Hospital Research Institute Inc
Publication of CA2967037A1 publication Critical patent/CA2967037A1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9486—Analgesics, e.g. opiates, aspirine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Emergency Medicine (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
CA2967037A 2014-12-03 2015-12-03 Anti-acetaminophen antibodies and acetaminophen protein adducts Pending CA2967037A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462086923P 2014-12-03 2014-12-03
US62/086,923 2014-12-03
PCT/US2015/063786 WO2016090163A2 (en) 2014-12-03 2015-12-03 Anti-acetaminophen antibodies and acetaminophen protein adducts

Publications (1)

Publication Number Publication Date
CA2967037A1 true CA2967037A1 (en) 2016-06-09

Family

ID=56092671

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2967037A Pending CA2967037A1 (en) 2014-12-03 2015-12-03 Anti-acetaminophen antibodies and acetaminophen protein adducts

Country Status (7)

Country Link
US (2) US10570216B2 (enExample)
EP (1) EP3227681B1 (enExample)
JP (2) JP6785239B2 (enExample)
AU (2) AU2015358373B2 (enExample)
CA (1) CA2967037A1 (enExample)
ES (1) ES2841904T3 (enExample)
WO (1) WO2016090163A2 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10351897B2 (en) 2014-02-14 2019-07-16 Bioventures, Llc Acetaminophen adducts and methods of use thereof
AU2015358373B2 (en) 2014-12-03 2021-05-27 Arkansas Children's Research Institute Anti-acetaminophen antibodies and acetaminophen protein adducts
CN112980808B (zh) * 2019-12-12 2024-10-29 深圳迈瑞生物医疗电子股份有限公司 尿酸酶、及其制备方法和用途
CN113248596B (zh) * 2021-04-15 2022-12-16 华南农业大学 一种可同时检测对乙酰氨基酚和非那西丁的人工抗原、抗体及其制备方法和应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5103021A (en) 1982-04-02 1992-04-07 Syntex (U.S.A.) Inc. Acetaminophen analogs, antigens, and antibodies
US4424150A (en) 1982-04-02 1984-01-03 Syva Company Acetaminophen analogs, antigens, and antibodies
DE1248112T1 (de) 1987-04-27 2003-03-20 Inverness Medical Switzerland Immunochromatographische Spezifischebindungsassayvorrichtung
US6352862B1 (en) 1989-02-17 2002-03-05 Unilever Patent Holdings B.V. Analytical test device for imuno assays and methods of using same
EP0674178B1 (en) 1990-11-20 2002-08-28 Dade Behring Marburg GmbH Cyclosporin immunoassay
US6905882B2 (en) 1992-05-21 2005-06-14 Biosite, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membranes
US5747352A (en) 1994-05-23 1998-05-05 Beckman Instruments, Inc. Reagents and methods for the rapid and quantitative assay of pharmacological agents
US5620890A (en) 1995-03-14 1997-04-15 The United States Of America As Represented By The Secretary Of Agriculture Monoclonal antibodies to hygromycin B and the method of making the same
US20040185040A1 (en) 2001-11-21 2004-09-23 Celltech R & D Limited Modulating immune responses
US20110004955A1 (en) * 2008-01-30 2011-01-06 Monsanto Technology Llc Transgenic plants with enhanced agronomic traits
US9029636B2 (en) * 2008-02-05 2015-05-12 Monsanto Technology Llc Isolated novel nucleic acid and protein molecules from soy and methods of using those molecules to generate transgenic plants with enhanced agronomic traits
WO2009131998A1 (en) 2008-04-21 2009-10-29 The Board Of Trustees Of The University Of Arkansas Acetaminophen-protein adduct assay device and method
WO2010083179A2 (en) 2009-01-16 2010-07-22 Monsanto Technology Llc Isolated novel nucleic acid and protein molecules from soybeans and methods of using those molecules to generate transgenic plants with enhanced agronomic traits
WO2011020529A2 (en) * 2009-08-19 2011-02-24 Merck Patent Gmbh Antibodies for the detection of integrin complexes in ffpe material
EP2993183B1 (en) 2010-02-16 2020-02-26 Österreichische Akademie der Wissenschaften Anti-hpv e7 antibodies
US20110214205A1 (en) * 2010-02-26 2011-09-01 Monsanto Technology Llc. Isolated Novel Nucleic Acid and Protein Molecules from Foxtail Millet and Methods of Using Those Molecules to Generate Transgenic Plants with Enhanced Agronomic Traits
EP3096142A3 (en) * 2011-04-29 2017-03-08 Celgene Corporation Methods for the treatment of cancer and inflammatory diseases using cereblon as a predictor
GEP201706737B (en) 2012-04-27 2017-09-25 Millennium Pharm Inc Anti-gcc antibody molecules and use of same to test for susceptibility to gcc-targeted therapy
US10351897B2 (en) 2014-02-14 2019-07-16 Bioventures, Llc Acetaminophen adducts and methods of use thereof
AU2015358373B2 (en) 2014-12-03 2021-05-27 Arkansas Children's Research Institute Anti-acetaminophen antibodies and acetaminophen protein adducts

Also Published As

Publication number Publication date
US20170362340A1 (en) 2017-12-21
US11566081B2 (en) 2023-01-31
WO2016090163A2 (en) 2016-06-09
US10570216B2 (en) 2020-02-25
JP6785239B2 (ja) 2020-11-18
AU2015358373A1 (en) 2017-05-25
JP2017538786A (ja) 2017-12-28
EP3227681A2 (en) 2017-10-11
AU2015358373A9 (en) 2021-05-27
US20200131278A1 (en) 2020-04-30
JP7072022B2 (ja) 2022-05-19
WO2016090163A3 (en) 2016-08-25
AU2021215156A1 (en) 2021-09-02
JP2020189843A (ja) 2020-11-26
ES2841904T3 (es) 2021-07-12
EP3227681A4 (en) 2018-06-13
AU2015358373B2 (en) 2021-05-27
EP3227681B1 (en) 2020-10-21

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