CA2961531A1 - Sgc stimulators - Google Patents
Sgc stimulators Download PDFInfo
- Publication number
- CA2961531A1 CA2961531A1 CA2961531A CA2961531A CA2961531A1 CA 2961531 A1 CA2961531 A1 CA 2961531A1 CA 2961531 A CA2961531 A CA 2961531A CA 2961531 A CA2961531 A CA 2961531A CA 2961531 A1 CA2961531 A1 CA 2961531A1
- Authority
- CA
- Canada
- Prior art keywords
- ring
- alkyl
- membered heteroaryl
- membered heterocyclic
- independently selected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462051620P | 2014-09-17 | 2014-09-17 | |
| US62/051,620 | 2014-09-17 | ||
| US201562204672P | 2015-08-13 | 2015-08-13 | |
| US62/204,672 | 2015-08-13 | ||
| PCT/US2015/050458 WO2016044441A1 (en) | 2014-09-17 | 2015-09-16 | Sgc stimulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2961531A1 true CA2961531A1 (en) | 2016-03-24 |
Family
ID=54293334
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2961531A Abandoned CA2961531A1 (en) | 2014-09-17 | 2015-09-16 | Sgc stimulators |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10047095B2 (https=) |
| EP (1) | EP3194395B1 (https=) |
| JP (1) | JP2017527605A (https=) |
| KR (1) | KR20170055531A (https=) |
| CN (1) | CN107223125B (https=) |
| AU (1) | AU2015317818A1 (https=) |
| BR (1) | BR112017005248A2 (https=) |
| CA (1) | CA2961531A1 (https=) |
| EA (1) | EA201790627A1 (https=) |
| IL (1) | IL251115A0 (https=) |
| MX (1) | MX2017003517A (https=) |
| WO (1) | WO2016044441A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3194386A2 (en) * | 2014-09-17 | 2017-07-26 | Ironwood Pharmaceuticals, Inc. | Sgc stimulators |
| AU2016371762A1 (en) | 2015-12-14 | 2018-06-21 | Cyclerion Therapeutics, Inc. | Use of sGC stimulators for the treatment of gastrointestinal sphincter dysfunction |
| CN109563077B (zh) | 2016-07-07 | 2026-03-10 | 赛克里翁治疗有限公司 | 用于制备可溶性鸟苷酸环化酶刺激剂的新方法 |
| CA3039735A1 (en) | 2016-10-11 | 2018-04-19 | Bayer Pharma Aktiengesellschaft | Combination containing sgc activators and mineralocorticoid receptor antagonists |
| US10918639B2 (en) | 2016-10-11 | 2021-02-16 | Bayer Pharma Aktiengesellschaft | Combination containing SGC stimulators and mineralocorticoid receptor antagonists |
| TW201822637A (zh) | 2016-11-07 | 2018-07-01 | 德商拜耳廠股份有限公司 | 用於控制動物害蟲的經取代磺醯胺類 |
| WO2018111795A2 (en) | 2016-12-13 | 2018-06-21 | Ironwood Pharmaceuticals, Inc. | Use of sgc stimulators for the treatment of esophageal motility disorders |
| JP7204758B2 (ja) * | 2017-11-08 | 2023-01-16 | オムニペプ・エスタブリッシュメント | 糖尿病性足の場合における組織酸素化を増強するための医療用製剤とその使用 |
| MA71753A (fr) * | 2018-01-10 | 2025-05-30 | Cyclerion Therapeutics, Inc. | Nouveaux procédés et intermédiaires pour la préparation de stimulateurs de guanylate cyclase soluble |
| CA3100096A1 (en) | 2018-05-15 | 2019-11-21 | Bayer Aktiengesellschaft | 1,3-thiazol-2-yl substituted benzamides for the treatment of diseases associated with nerve fiber sensitization |
| KR20210031931A (ko) | 2018-07-11 | 2021-03-23 | 사이클리온 테라퓨틱스, 인크. | 미토콘드리아 장애의 치료를 위한 sGC 자극제의 용도 |
| US12478624B2 (en) | 2019-10-02 | 2025-11-25 | Tolremo Therapeutics Ag | Heterocyclic derivatives, pharmaceutical compositions and their use in the treatment or amelioration of cancer |
| IL299344A (en) | 2020-06-25 | 2023-02-01 | Tolremo Therapeutics Ag | Combination of a cbp/p300 bromodomain inhibitor and a kras inhibitor for the treatment of cancer |
| CA3184062A1 (en) * | 2020-06-25 | 2021-12-30 | Stefanie Fluckiger-Mangual | Heterocyclic derivatives, pharmaceutical compositions and their use in the treatment, amelioration or prevention of fibrotic disease |
| BR112023020538A2 (pt) | 2021-04-07 | 2024-01-23 | Tolremo Therapeutics Ag | Derivados heterocíclicos, composições farmacêuticas e seus usos no tratamento ou na melhoria de câncer |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4544999B2 (ja) * | 2002-11-25 | 2010-09-15 | 持田製薬株式会社 | ４−ヒドロキシピペリジン誘導体を有効成分とする呼吸器疾患治療剤 |
| CN101679371A (zh) * | 2006-12-04 | 2010-03-24 | 艾美罗股份公司 | 作为腺苷受体拮抗剂的取代的嘧啶 |
| AR088020A1 (es) * | 2010-06-30 | 2014-05-07 | Ironwood Pharmaceuticals Inc | Compuestos heterociclicos como estimuladores de sgc |
| EP2637659B1 (en) * | 2010-11-09 | 2016-05-18 | Ironwood Pharmaceuticals, Inc. | Sgc stimulators |
| DE102012200360A1 (de) | 2012-01-11 | 2013-07-11 | Bayer Intellectual Property Gmbh | Substituierte Triazine und ihre Verwendung |
| US9487508B2 (en) * | 2012-09-19 | 2016-11-08 | Ironwood Pharmaceuticals, Inc. | SGC stimulators |
| SI2970243T1 (sl) * | 2013-03-15 | 2020-04-30 | Cyclerion Therapeutics, Inc. | SGC stimulatorji |
| WO2015106268A1 (en) * | 2014-01-13 | 2015-07-16 | Ironwood Pharmaceuticals, Inc. | USE OF sGC STIMULATORS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS |
-
2015
- 2015-09-16 KR KR1020177010076A patent/KR20170055531A/ko not_active Withdrawn
- 2015-09-16 EA EA201790627A patent/EA201790627A1/ru unknown
- 2015-09-16 JP JP2017515198A patent/JP2017527605A/ja active Pending
- 2015-09-16 WO PCT/US2015/050458 patent/WO2016044441A1/en not_active Ceased
- 2015-09-16 CA CA2961531A patent/CA2961531A1/en not_active Abandoned
- 2015-09-16 BR BR112017005248A patent/BR112017005248A2/pt not_active IP Right Cessation
- 2015-09-16 MX MX2017003517A patent/MX2017003517A/es unknown
- 2015-09-16 AU AU2015317818A patent/AU2015317818A1/en not_active Abandoned
- 2015-09-16 EP EP15779068.4A patent/EP3194395B1/en active Active
- 2015-09-16 CN CN201580062215.9A patent/CN107223125B/zh not_active Expired - Fee Related
- 2015-09-16 US US15/511,897 patent/US10047095B2/en active Active
-
2017
- 2017-03-13 IL IL251115A patent/IL251115A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2016044441A1 (en) | 2016-03-24 |
| US10047095B2 (en) | 2018-08-14 |
| EP3194395B1 (en) | 2019-12-04 |
| JP2017527605A (ja) | 2017-09-21 |
| IL251115A0 (en) | 2017-04-30 |
| EP3194395A1 (en) | 2017-07-26 |
| KR20170055531A (ko) | 2017-05-19 |
| EA201790627A1 (ru) | 2017-09-29 |
| BR112017005248A2 (pt) | 2017-12-12 |
| US20170291902A1 (en) | 2017-10-12 |
| CN107223125B (zh) | 2019-09-27 |
| CN107223125A (zh) | 2017-09-29 |
| MX2017003517A (es) | 2017-07-28 |
| AU2015317818A1 (en) | 2017-03-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20200916 |