CA2943242A1 - Bi-specific antigen-binding polypeptides - Google Patents
Bi-specific antigen-binding polypeptides Download PDFInfo
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- CA2943242A1 CA2943242A1 CA2943242A CA2943242A CA2943242A1 CA 2943242 A1 CA2943242 A1 CA 2943242A1 CA 2943242 A CA2943242 A CA 2943242A CA 2943242 A CA2943242 A CA 2943242A CA 2943242 A1 CA2943242 A1 CA 2943242A1
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- antigen
- amino acid
- binding polypeptide
- domain
- acid sequence
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- C07K2317/622—Single chain antibody (scFv)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/64—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a combination of variable region and constant region components
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- Health & Medical Sciences (AREA)
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- Genetics & Genomics (AREA)
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- Engineering & Computer Science (AREA)
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461968437P | 2014-03-21 | 2014-03-21 | |
| US61/968,437 | 2014-03-21 | ||
| PCT/US2015/021668 WO2015143271A1 (en) | 2014-03-21 | 2015-03-20 | Bi-specific antigen-binding polypeptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2943242A1 true CA2943242A1 (en) | 2015-09-24 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CA2943242A Pending CA2943242A1 (en) | 2014-03-21 | 2015-03-20 | Bi-specific antigen-binding polypeptides |
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| Country | Link |
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| US (2) | US10202462B2 (enExample) |
| EP (2) | EP3119812B1 (enExample) |
| JP (3) | JP6640181B2 (enExample) |
| KR (1) | KR102399028B1 (enExample) |
| CN (2) | CN106164094B (enExample) |
| AU (2) | AU2015231155B2 (enExample) |
| CA (1) | CA2943242A1 (enExample) |
| ES (1) | ES2800674T3 (enExample) |
| RU (1) | RU2723940C2 (enExample) |
| WO (1) | WO2015143271A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| AU2015231155B2 (en) * | 2014-03-21 | 2020-11-12 | X-Body, Inc. | Bi-specific antigen-binding polypeptides |
| CN106279435B (zh) * | 2016-08-16 | 2019-06-07 | 新乡医学院 | 靶向VEGF与mucin1的抗肿瘤疫苗、编码基因、表达载体、表达工程菌及应用 |
| AU2019340366B2 (en) | 2018-09-10 | 2025-01-02 | Mirati Therapeutics, Inc. | Combination therapies |
| US12098206B2 (en) | 2018-10-05 | 2024-09-24 | Seoul National University R&Db Foundation | PDGF receptor antibody and use thereof |
| US20230183353A1 (en) * | 2020-05-21 | 2023-06-15 | Zydus Lifesciences Limited | Fc variant and preparation thereof |
| CA3226059A1 (en) * | 2021-06-29 | 2023-01-05 | Elpis Biopharmaceuticals | Anti-nectin4 antibodies and multi-specific protein complexes comprising such |
| KR20230060546A (ko) * | 2021-10-22 | 2023-05-04 | 상트네어바이오사이언스 주식회사 | 두개의 Fc 도메인을 포함하는 항원 결합 단백질 및 이의 용도 |
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2015
- 2015-03-20 AU AU2015231155A patent/AU2015231155B2/en not_active Ceased
- 2015-03-20 JP JP2017501125A patent/JP6640181B2/ja active Active
- 2015-03-20 KR KR1020167028833A patent/KR102399028B1/ko active Active
- 2015-03-20 WO PCT/US2015/021668 patent/WO2015143271A1/en not_active Ceased
- 2015-03-20 CN CN201580014693.2A patent/CN106164094B/zh active Active
- 2015-03-20 RU RU2016141285A patent/RU2723940C2/ru active
- 2015-03-20 CN CN202110389203.4A patent/CN113150163A/zh active Pending
- 2015-03-20 US US14/664,018 patent/US10202462B2/en active Active
- 2015-03-20 ES ES15764568T patent/ES2800674T3/es active Active
- 2015-03-20 EP EP15764568.0A patent/EP3119812B1/en active Active
- 2015-03-20 EP EP20171202.3A patent/EP3712176A1/en not_active Withdrawn
- 2015-03-20 CA CA2943242A patent/CA2943242A1/en active Pending
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2019
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- 2019-12-25 JP JP2019233759A patent/JP7048567B2/ja not_active Expired - Fee Related
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2021
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2022
- 2022-01-20 JP JP2022007025A patent/JP2022062083A/ja active Pending
Also Published As
| Publication number | Publication date |
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| US20190248918A1 (en) | 2019-08-15 |
| JP2022062083A (ja) | 2022-04-19 |
| EP3119812B1 (en) | 2020-04-29 |
| JP7048567B2 (ja) | 2022-04-05 |
| RU2016141285A3 (enExample) | 2019-05-15 |
| ES2800674T3 (es) | 2021-01-04 |
| EP3119812A1 (en) | 2017-01-25 |
| EP3712176A1 (en) | 2020-09-23 |
| AU2015231155A1 (en) | 2016-11-03 |
| KR20160135764A (ko) | 2016-11-28 |
| EP3119812A4 (en) | 2017-10-25 |
| US20150299335A1 (en) | 2015-10-22 |
| RU2016141285A (ru) | 2018-04-26 |
| WO2015143271A1 (en) | 2015-09-24 |
| JP6640181B2 (ja) | 2020-02-05 |
| CN113150163A (zh) | 2021-07-23 |
| JP2020072686A (ja) | 2020-05-14 |
| RU2723940C2 (ru) | 2020-06-18 |
| AU2015231155B2 (en) | 2020-11-12 |
| US10202462B2 (en) | 2019-02-12 |
| US11814441B2 (en) | 2023-11-14 |
| KR102399028B1 (ko) | 2022-05-17 |
| CN106164094A (zh) | 2016-11-23 |
| AU2021200347A1 (en) | 2021-03-18 |
| JP2017511152A (ja) | 2017-04-20 |
| CN106164094B (zh) | 2021-05-14 |
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